Author results

3KUL
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KINASE DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 8 (EPHA8)
Descriptor:Ephrin type-A receptor 8, SULFATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Walker, J.R., Yermekbayeva, L., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2009-11-27
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinase Domain of Human Ephrin Type-A Receptor 8 (Epha8)
To be Published
3NRU
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LIGAND BINDING DOMAIN OF EPHA7
Descriptor:Ephrin receptor, SULFATE ION, CHLORIDE ION
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.
Deposit date:2010-06-30
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ephrin A7 ligand binding domain
To be Published
3P1I
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LIGAND BINDING DOMAIN OF HUMAN EPHRIN TYPE-B RECEPTOR 3
Descriptor:Ephrin type-B receptor 3, SULFATE ION, CHLORIDE ION
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-09-30
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ligand Binding Domain of Human Ephb3
To be Published
3QIR
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CRYSTAL STRUCTURE OF PIWIL2 PAZ DOMAIN
Descriptor:Piwi-like protein 2
Authors:Dong, A., Xu, C., Bian, C., Wernimont, A.K., Kania, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-01-27
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of PIWIL2 PAZ domain
To be Published
3S93
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CRYSTAL STRUCTURE OF CONSERVED MOTIF IN TDRD5
Descriptor:Tudor domain-containing protein 5, UNKNOWN ATOM OR ION
Authors:Chao, X., Tempel, W., Bian, C., Kania, J., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of conserved motif in TDRD5
to be published
4PYZ
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CRYSTAL STRUCTURE OF THE FIRST TWO UBL DOMAINS OF DEUBIQUITYLASE USP7
Descriptor:Ubiquitin carboxyl-terminal hydrolase 7, UNKNOWN ATOM OR ION
Authors:Walker, J.R., Dong, A., Ong, M.S., Dhe-Paganon, S., Kania, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Tong, Y., Structural Genomics Consortium (SGC)
Deposit date:2014-03-28
Release date:2014-04-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of the first two Ubl domains of Deubiquitylase USP7
to be published
3O70
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PHD-TYPE ZINC FINGER OF HUMAN PHD FINGER PROTEIN 13
Descriptor:PHD finger protein 13, GLYCEROL, ZINC ION
Authors:Lam, R., Bian, C.B., Xu, C., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-07-29
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
Elife, 5, 2016
3PFS
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PWWP DOMAIN OF HUMAN BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3
Descriptor:Bromodomain and PHD finger-containing protein 3, ZINC ION, SULFATE ION
Authors:Lam, R., Zeng, H., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2010-10-29
Release date:2010-11-10
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
3PG6
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THE CARBOXYL TERMINAL DOMAIN OF HUMAN DELTEX 3-LIKE
Descriptor:E3 ubiquitin-protein ligase DTX3L, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Walker, J.R., Obiero, J., Kania, J., Schuler, H., Bountra, C., Weigelt, J., Edwards, A.M., Arrowsmith, C.H., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-10-30
Release date:2010-12-01
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fold of the conserved DTC domain in Deltex proteins.
Proteins, 80, 2012
3PMT
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CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN TUDOR DOMAIN-CONTAINING PROTEIN 3
Descriptor:Tudor domain-containing protein 3, TETRAETHYLENE GLYCOL
Authors:Lam, R., Bian, C.B., Guo, Y.H., Xu, C., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-11-18
Release date:2010-12-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30.
Plos One, 7, 2012
3QMB
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3', ZINC ION, ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMC
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*CP*CP*GP*CP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*GP*CP*GP*GP*TP*GP*GP*C)-3', ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMD
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*AP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*CP*GP*TP*TP*GP*GP*C)-3'), ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3TYY
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CRYSTAL STRUCTURE OF HUMAN LAMIN-B1 COIL 2 SEGMENT
Descriptor:Lamin-B1
Authors:Lam, R., Xu, C., Bian, C.B., Mackenzie, F., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-09-26
Release date:2011-10-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
3UMN
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CRYSTAL STRUCTURE OF LAMIN-B1
Descriptor:Lamin-B1
Authors:Xu, C., Bian, C.B., Amaya, M.F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-11-14
Release date:2011-11-30
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
3V2O
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CRYSTAL STRUCTURE OF THE PEPTIDE BOUND COMPLEX OF THE ANKYRIN REPEAT DOMAINS OF HUMAN ANKRA2
Descriptor:Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2X
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CRYSTAL STRUCTURE OF THE PEPTIDE BOUND COMPLEX OF THE ANKYRIN REPEAT DOMAINS OF HUMAN ANKRA2
Descriptor:Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V30
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CRYSTAL STRUCTURE OF THE PEPTIDE BOUND COMPLEX OF THE ANKYRIN REPEAT DOMAINS OF HUMAN RFXANK
Descriptor:DNA-binding protein RFXANK, DNA-binding protein RFX5
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V31
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CRYSTAL STRUCTURE OF THE PEPTIDE BOUND COMPLEX OF THE ANKYRIN REPEAT DOMAINS OF HUMAN ANKRA2
Descriptor:Ankyrin repeat family A protein 2, Histone deacetylase 4, CHLORIDE ION, ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
5EGS
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HUMAN PRMT6 WITH BOUND FRAGMENT-TYPE INHIBITOR
Descriptor:Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, 2-[4-(phenylmethyl)piperidin-1-yl]ethanamine
Authors:Steuber, H., Egner, U., Kania, J., Wu, H., Brown, P.J.
Deposit date:2015-10-27
Release date:2016-02-03
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.
J.Med.Chem., 59, 2016