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1L1M
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BU of 1l1m by Molmil
SOLUTION STRUCTURE OF A DIMER OF LAC REPRESSOR DNA-BINDING DOMAIN COMPLEXED TO ITS NATURAL OPERATOR O1
Descriptor: 5'-D(*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3', Lactose operon repressor
Authors:Kalodimos, C.G, Bonvin, A.M.J.J, Salinas, R.K, Wechselberger, R, Boelens, R, Kaptein, R.
Deposit date:2002-02-19
Release date:2002-06-26
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.
EMBO J., 21, 2002
1OSL
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BU of 1osl by Molmil
Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
Descriptor: 5'-D(*CP*GP*AP*TP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*AP*TP*CP*G)-3', Lactose operon repressor
Authors:Kalodimos, C.G, Bonvin, A.M.J.J, Boelens, R, Kaptein, R.
Deposit date:2003-03-20
Release date:2004-05-04
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.
Science, 305, 2004
6AMW
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BU of 6amw by Molmil
Abl1b Regulatory Module 'Activating' conformation
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Rossi, P, Saleh, T.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
6AMV
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BU of 6amv by Molmil
Abl 1b Regulatory Module 'inhibiting state'
Descriptor: Tyrosine-protein kinase ABL1
Authors:Kalodimos, C.G, Saleh, T, Rossi, P.
Deposit date:2017-08-11
Release date:2017-09-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Atomic view of the energy landscape in the allosteric regulation of Abl kinase.
Nat. Struct. Mol. Biol., 24, 2017
2L3S
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BU of 2l3s by Molmil
Structure of the autoinhibited Crk
Descriptor: Autoinhibited Crk protein
Authors:Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
Deposit date:2010-09-21
Release date:2010-12-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
2L3P
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BU of 2l3p by Molmil
Structure of the prolyl cis isomer of the Crk Protein
Descriptor: Cis isomer of Crk protein
Authors:Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R.
Deposit date:2010-09-21
Release date:2010-12-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
8FTW
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BU of 8ftw by Molmil
FliT-FliJ fusion complex
Descriptor: Flagellar FliT protein, Flagellar FliJ protein fusion
Authors:Rossi, P, Kalodimos, C.G.
Deposit date:2023-01-13
Release date:2023-07-05
Last modified:2023-11-01
Method:SOLUTION NMR
Cite:Chaperone Recycling in Late-Stage Flagellar Assembly.
J.Mol.Biol., 435, 2023
8FTX
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BU of 8ftx by Molmil
FlgN-FliJ fusion complex
Descriptor: Flagella biosynthesis chaperone FlgN, Flagellar FliJ protein fusion
Authors:Rossi, P, Kalodimos, C.G.
Deposit date:2023-01-13
Release date:2023-07-05
Last modified:2023-11-01
Method:SOLUTION NMR
Cite:Chaperone Recycling in Late-Stage Flagellar Assembly.
J.Mol.Biol., 435, 2023
5KS6
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BU of 5ks6 by Molmil
Recognition and targeting mechanisms by chaperones in flagella assembly and operation
Descriptor: Flagellar protein FliT
Authors:Khanra, N.K, Rossi, P, Economou, A, Kalodimos, C.G.
Deposit date:2016-07-07
Release date:2016-08-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Recognition and targeting mechanisms by chaperones in flagellum assembly and operation.
Proc.Natl.Acad.Sci.USA, 113, 2016
2WC2
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BU of 2wc2 by Molmil
Nmr structure of catabolite activator protein in the unliganded state
Descriptor: CATABOLITE GENE ACTIVATOR
Authors:Popovych, N, Tzeng, S.R, Kalodimos, C.G.
Deposit date:2009-03-06
Release date:2009-04-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Basis for Camp-Mediated Allosteric Control of the Catabolite Activator Protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
2VDA
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BU of 2vda by Molmil
Solution structure of the SecA-signal peptide complex
Descriptor: MALTOPORIN, TRANSLOCASE SUBUNIT SECA
Authors:Gelis, I, Bonvin, A.M.J.J, Keramisanou, D, Koukaki, M, Gouridis, G, Karamanou, S, Economou, A, Kalodimos, C.G.
Deposit date:2007-10-01
Release date:2007-11-27
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Structural Basis for Signal-Sequence Recognition by the Translocase Motor Seca as Determined by NMR
Cell(Cambridge,Mass.), 131, 2007
4BH9
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BU of 4bh9 by Molmil
A structural model of CAP mutant (T127L and S128I) in the apo state
Descriptor: cAMP-activated global transcriptional regulator CRP
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-03-30
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4BHP
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BU of 4bhp by Molmil
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
Descriptor: CAMP RECEPTOR PROTEIN
Authors:Tzeng, S.R, Kalodimos, C.G.
Deposit date:2013-04-04
Release date:2013-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Allosteric Inhibition Through Suppression of Transient Conformational States.
Nat.Chem.Biol., 9, 2013
6XR6
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BU of 6xr6 by Molmil
Abl 1b isoform active state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XR7
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BU of 6xr7 by Molmil
Abl isoform 1b inactive1 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-11
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
6XRG
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BU of 6xrg by Molmil
Abl 1b isoform inactive2 state
Descriptor: Tyrosine-protein kinase ABL1
Authors:Xie, T, Saleh, T, Rossi, P, Kalodimos, C.G.
Deposit date:2020-07-12
Release date:2020-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational states dynamically populated by a kinase determine its function.
Science, 370, 2020
7MZZ
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BU of 7mzz by Molmil
AUGbeta - FAM150A - ALKL1 60-128
Descriptor: ALK and LTK ligand 1
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7N00
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BU of 7n00 by Molmil
Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha
Descriptor: ALK and LTK ligand 2, ALK tyrosine kinase receptor
Authors:Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZY
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BU of 7mzy by Molmil
Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986
Descriptor: ACETATE ION, ALK tyrosine kinase receptor
Authors:Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZW
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BU of 7mzw by Molmil
Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025
Descriptor: ALK tyrosine kinase receptor
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-12-08
Last modified:2021-12-15
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7MZX
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BU of 7mzx by Molmil
AUGalpha - FAM150B - ALKL2 77-152
Descriptor: ALK and LTK ligand 2
Authors:Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
Deposit date:2021-05-24
Release date:2021-11-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
6CH1
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BU of 6ch1 by Molmil
Crystal structure of the cytoplasmic domain of FlhA in monomeric form
Descriptor: 1,2-ETHANEDIOL, Flagellar biosynthesis protein FlhA
Authors:Xing, Q, Shi, K, Kalodimos, C.G.
Deposit date:2018-02-21
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
6CH3
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BU of 6ch3 by Molmil
Crystal structure of the cytoplasmic domain of FlhA and FliS-FliC complex
Descriptor: Flagellar biosynthesis protein FlhA, Flagellar secretion chaperone FliS,Flagellin
Authors:Xing, Q, Shi, K, Kalodimos, C.G.
Deposit date:2018-02-21
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
6CH2
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BU of 6ch2 by Molmil
Crystal structure of the cytoplasmic domain of FlhA and FliT-FliD complex
Descriptor: Flagellar biosynthesis protein FlhA, Flagellar hook-associated protein 2,Flagellar protein FliT, GLYCEROL
Authors:Xing, Q, Shi, K, Kalodimos, C.G.
Deposit date:2018-02-21
Release date:2018-05-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system.
Nat Commun, 9, 2018
6D6S
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BU of 6d6s by Molmil
Solution structure of Trigger Factor dimer
Descriptor: Trigger factor
Authors:Saio, T, Kawagoe, S, Ishimori, K, Kalodimos, C.G.
Deposit date:2018-04-22
Release date:2018-06-13
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Oligomerization of a molecular chaperone modulates its activity.
Elife, 7, 2018

 

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