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3VI5
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HUMAN HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITOR COMPLEX STRUCTURES
Descriptor:Hematopoietic prostaglandin D synthase, GLUTATHIONE, CALCIUM ION, ...
Authors:Kado, Y., Inoue, T.
Deposit date:2011-09-21
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human hematopoietic prostaglandin D synthase inhibitor complex structures
J.Biochem., 151, 2012
3VI7
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HUMAN HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITOR COMPLEX STRUCTURES
Descriptor:Hematopoietic prostaglandin D synthase, GLUTATHIONE, CIBACRON BLUE, ...
Authors:Kado, Y., Inoue, T.
Deposit date:2011-09-21
Release date:2012-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human hematopoietic prostaglandin D synthase inhibitor complex structures
J.Biochem., 151, 2012
5AZ2
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF 9E5, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR HUMAN EPIREGULIN
Descriptor:anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain
Authors:Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T.
Deposit date:2015-09-16
Release date:2015-12-09
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
5E8D
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CRYSTAL STRUCTURE OF HUMAN EPIREGULIN IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY 9E5
Descriptor:Proepiregulin, anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain, ...
Authors:Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T.
Deposit date:2015-10-14
Release date:2015-12-09
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
3APG
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CRYSTAL STRUCTURE OF HYPERTHERMOPHILIC BETA-GLUCOSIDASE FROM PYROCOCCUS FURIOSUS
Descriptor:Beta-glucosidase, GLYCEROL
Authors:Kado, Y., Inoue, T., Ishikawa, K.
Deposit date:2010-10-15
Release date:2011-10-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of hyperthermophilic beta-glucosidase from pyrococcus furiosus
TO BE PUBLISHED
1V40
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FIRST INHIBITOR COMPLEX STRUCTURE OF HUMAN HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE
Descriptor:Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, GLUTATHIONE, ...
Authors:Inoue, T., Okano, Y., Kado, Y., Aritake, K., Irikura, D., Uodome, N., Kinugasa, S., Okazaki, N., Matsumura, H., Kai, Y., Urade, Y.
Deposit date:2003-11-07
Release date:2004-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase.
J.Biochem.(Tokyo), 135, 2004
3WIH
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CRYSTAL STRUCTURE OF THE THIRD FIBRONECTIN DOMAIN (FN3) OF HUMAN ROBO1 IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY B2212A.
Descriptor:Roundabout homolog 1, anti-human ROBO1 antibody B2212A Fab light chain, anti-human ROBO1 antibody B2212A Fab heavy chain, ...
Authors:Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T.
Deposit date:2013-09-12
Release date:2015-01-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
3WII
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF B2212A, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR THE THIRD FIBRONECTIN DOMAIN (FN3) OF HUMAN ROBO1.
Descriptor:anti-human ROBO1 antibody B2212A Fab light chain, anti-human ROBO1 antibody B2212A Fab heavy chain
Authors:Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, S., Nakakido, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T.
Deposit date:2013-09-12
Release date:2015-01-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
2CVD
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE COMPLEXED WITH HQL-79
Descriptor:Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, GLUTATHIONE, ...
Authors:Aritake, K., Kado, Y., Inoue, T., Miyano, M., Urade, Y.
Deposit date:2005-06-02
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D Synthase.
J.Biol.Chem., 281, 2006
3WO8
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CRYSTAL STRUCTURE OF THE BETA-N-ACETYLGLUCOSAMINIDASE FROM THERMOTOGA MARITIMA
Descriptor:Beta-N-acetylglucosaminidase
Authors:Mine, S., Kado, Y., Watanabe, M., Inoue, T., Ishikawa, K.
Deposit date:2013-12-20
Release date:2014-12-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The structure of hyperthermophilic beta-N-acetylglucosaminidase reveals a novel dimer architecture associated with the active site.
Febs J., 281, 2014
6A76
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF B5209B, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1
Descriptor:Light chain of the anti-human Robo1 antibody B5209B Fab, Heavy chain of the anti-human Robo1 antibody B5209B Fab, GLYCEROL, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A77
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain of the anti-human Robo1 antibody B5209B Fab, Heavy chain of the anti-human Robo1 antibody B5209B Fab
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A78
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE SCFV FRAGMENT OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain region of the anti-human Robo1 antibody B5209B scFv, Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A79
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE MUTANT SCFV FRAGMENT (P103A) OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain region of the anti-human Robo1 antibody B5209B scFv, Heavy chain of the anti-human Robo1 antibody B5209B scFv, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Yokota, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
3A2V
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PEROXIREDOXIN (C207S) FROM AEROPYRUM PERNIX K1 COMPLEXED WITH HYDROGEN PEROXIDE
Descriptor:Probable peroxiredoxin, PEROXIDE ION
Authors:Nakamura, T., Kado, Y., Yamaguchi, F., Ishikawa, K., Matsumura, H., Inoue, T.
Deposit date:2009-06-04
Release date:2009-10-27
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide
J.Biochem., 147, 2010
3A2W
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PEROXIREDOXIN (C50S) FROM AEROPYTUM PERNIX K1 (PEROXIDE-BOUND FORM)
Descriptor:Probable peroxiredoxin, GLYCEROL, PEROXIDE ION
Authors:Nakamura, T., Kado, Y., Yamaguchi, F., Matsumura, H., Ishikawa, K., Inoue, T.
Deposit date:2009-06-04
Release date:2009-10-27
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide
J.Biochem., 147, 2010
3A2X
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PEROXIREDOXIN (C50S) FROM AEROPYRUM PERNIX K1 (ACETATE-BOUND FORM)
Descriptor:Probable peroxiredoxin, ACETATE ION
Authors:Nakamura, T., Kado, Y., Yamaguchi, F., Matsumura, H., Ishikawa, K., Inoue, T.
Deposit date:2009-06-04
Release date:2009-10-27
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide
J.Biochem., 147, 2010
3A5W
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PEROXIREDOXIN (WILD TYPE) FROM AEROPYRUM PERNIX K1 (REDUCED FORM)
Descriptor:Probable peroxiredoxin
Authors:Nakamura, T., Kado, Y., Yamaguchi, T., Matsumura, H., Ishikawa, K., Inoue, T.
Deposit date:2009-08-12
Release date:2009-10-27
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide
J.Biochem., 147, 2010
5NEN
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CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF LIPC, A MEMBRANE FUSION PROTEIN OF A TYPE I SECRETION SYSTEM
Descriptor:Lipase C
Authors:Murata, D., Akutsu, M., Takano, K.
Deposit date:2017-03-11
Release date:2017-11-22
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain.
Biochemistry, 56, 2017
5X7K
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CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAIN (NBD) OF LIPB, A ABC TRANSPORTER SUBUNIT OF A TYPE I SECRETION SYSTEM
Descriptor:Lipase B
Authors:Okano, H., Angkawidjaja, C., Takano, K.
Deposit date:2017-02-27
Release date:2017-11-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain
Biochemistry, 56, 2017
3A4W
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CRYSTAL STRUCTURES OF CATALYTIC SITE MUTANTS OF ACTIVE DOMAIN 2 OF THERMOSTABLE CHITINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH CHITO-OLIGOSACCHARIDES
Descriptor:Chitinase, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Tsuji, H., Nishimura, S., Inui, T., Ishikawa, K., Nakamura, T., Uegaki, K.
Deposit date:2009-07-22
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site
Febs J., 277, 2010
3A4X
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CRYSTAL STRUCTURES OF CATALYTIC SITE MUTANTS OF ACTIVE DOMAIN 2 OF THERMOSTABLE CHITINASE FROM PYROCOCCUS FURIOSUS COMPLEXED WITH CHITO-OLIGOSACCHARIDES
Descriptor:Chitinase, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Tsuji, H., Nishimura, S., Inui, T., Ishikawa, K., Nakamura, T., Uegaki, K.
Deposit date:2009-07-22
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site
Febs J., 277, 2010
3AFB
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CRYSTAL STRUCTURES OF CATALYTIC SITE MUTANTS OF ACTIVE DOMAIN 2 OF CHITINASE FROM PYROCOCCUS FURIOSUS
Descriptor:Putative chitinase, MAGNESIUM ION, GLYCEROL, ...
Authors:Tsuji, H.
Deposit date:2010-02-25
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site
Febs J., 277, 2010