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3ZYB
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION
分子名称:PA-I galactophilic lectin, GALA-LYS-PRO-LEUNH2, CALCIUM ION, ...
著者Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
登録日2011-08-19
公開日2011-09-21
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
3ZYF
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION
分子名称:PA-I GALACTOPHILIC LECTIN, CALCIUM ION, 1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE
著者Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
登録日2011-08-22
公開日2011-09-21
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (1.944 Å)
主引用文献A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
3ZYH
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALBG0 AT 1.5 A RESOLUTION
分子名称:PA-I galactophilic lectin, CALCIUM ION, 3-(beta-D-galactopyranosylthio)propanoic acid
著者Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
登録日2011-08-23
公開日2011-09-21
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A Glycopeptide Dendrimer Inhibitor of the Galactose Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms
Angew.Chem.Int.Ed.Engl., 50, 2011
4LJH
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH 1-METHYL-3-INDOLYL-B-D-GALACTOPYRANOSIDE AT 1.45 A RESOLUTION
分子名称:PA-I galactophilic lectin, CALCIUM ION, 1-methyl-1H-indol-3-ol, ...
著者Kadam, R.U., Stocker, A., Reymond, J.L.
登録日2013-07-04
公開日2013-10-30
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献CH-pi "T-Shape" Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
Acs Chem.Biol., 8, 2013
4LK6
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH CHLOROPHENOL RED-B-D-GALACTOPYRANOSIDE AT 2.86 A RESOLUTION
分子名称:PA-I galactophilic lectin, CALCIUM ION, 2-[(E)-(3-chloro-4-hydroxyphenyl)(3-chloro-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonic acid, ...
著者Kadam, R.U., Stocker, A., Reymond, J.L.
登録日2013-07-06
公開日2013-10-30
実験手法X-RAY DIFFRACTION (2.859 Å)
主引用文献CH-pi "T-Shape" Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
Acs Chem.Biol., 8, 2013
4LK7
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH RESORUFIN-B-D-GALACTOPYRANOSIDE AT 1.76 A RESOLUTION
分子名称:PA-I galactophilic lectin, CALCIUM ION, 7-hydroxy-3H-phenoxazin-3-one, ...
著者Kadam, R.U., Stocker, A., Reymond, J.L.
登録日2013-07-06
公開日2013-10-30
実験手法X-RAY DIFFRACTION (1.758 Å)
主引用文献CH-pi "T-Shape" Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA
Acs Chem.Biol., 8, 2013
4LKD
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-QRS AT 2.31 A RESOLUTION
分子名称:PA-I galactophilic lectin, peptide QRSA, BETA-D-GALACTOSE, ...
著者Kadam, R.U., Stocker, A., Reymond, J.-L.
登録日2013-07-07
公開日2013-12-18
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
4LKE
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-WRI AT 1.65 A RESOLUTION
分子名称:PA-I galactophilic lectin, peptide WRIA, BETA-D-GALACTOSE, ...
著者Kadam, R.U., Stocker, A., Reymond, J.-L.
登録日2013-07-07
公開日2013-12-18
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
4LKF
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-WKY AT 1.64 A RESOLUTION
分子名称:PA-I galactophilic lectin, peptide WKYL, BETA-D-GALACTOSE, ...
著者Kadam, R.U., Stocker, A., Reymond, J.-L.
登録日2013-07-07
公開日2013-12-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
5T6N
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CRYSTAL STRUCTURE OF THE A/HONG KONG/1/1968 (H3N2) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH THE ANTIVIRAL DRUG ARBIDOL
分子名称:Hemagglutinin HA1, Hemagglutinin HA2, N-ACETYL-D-GLUCOSAMINE, ...
著者Kadam, R.U., Wilson, I.A.
登録日2016-09-01
公開日2017-01-04
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.541 Å)
主引用文献Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T6S
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CRYSTAL STRUCTURE OF THE A/SHANGHAI/2/2013 (H7N9) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH THE ANTIVIRAL DRUG ARBIDOL
分子名称:Hemagglutinin HA1, Hemagglutinin HA2, N-ACETYL-D-GLUCOSAMINE, ...
著者Kadam, R.U., Wilson, I.A.
登録日2016-09-01
公開日2017-01-04
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W5S
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141019 (P5)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-ZCL-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-15
公開日2017-10-04
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.284 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W5U
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141037 (P4)
分子名称:Hemagglutinin, ACE-PH8-ORN-MLE-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-15
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6I
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141046 (P3)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6R
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP141099 (P6)
分子名称:Hemagglutinin, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-9WV, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.731 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6T
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP151070 (P7)
分子名称:Hemagglutinin, ACE-PH8-ORN-MLE-GLU-TYR-ZCL-GLU-TRP-LEU-SER-9WV, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6U
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CRYSTAL STRUCTURE OF THE A/PUERTO RICO/8/1934 (H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH CYCLIC PEPTIDE CP121068 (P2)
分子名称:Hemagglutinin, ACE-ARG-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, N-ACETYL-D-GLUCOSAMINE
著者Wilson, I.A., Kadam, R.U.
登録日2017-06-16
公開日2017-10-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
6CEX
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CRYSTAL STRUCTURE OF THE A/HONG KONG/1/1968 (H3N2) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE N-CYCLOHEXYLTAURINE
分子名称:Hemagglutinin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
著者wilson, I.A., Kadam, R.U.
登録日2018-02-12
公開日2018-04-04
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CF5
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CRYSTAL STRUCTURE OF THE A/VIET NAM/1203/2004(H5N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE N-CYCLOHEXYLTAURINE
分子名称:Hemagglutinin, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, N-ACETYL-D-GLUCOSAMINE, ...
著者Wilson, I.A., Kadam, R.U.
登録日2018-02-13
公開日2018-04-04
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CF7
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CRYSTAL STRUCTURE OF THE A/SOLOMON ISLANDS/3/2006(H1N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE JNJ4796
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kadam, R.U., Wilson, I.A.
登録日2018-02-13
公開日2019-02-13
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (2.719 Å)
主引用文献A small-molecule fusion inhibitor of influenza virus is orally active in mice
Science, 2019
6CFG
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CRYSTAL STRUCTURE OF THE A/VIETNAM/1203/2004 (H5N1) INFLUENZA VIRUS HEMAGGLUTININ IN COMPLEX WITH SMALL MOLECULE JNJ4796
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, N-[2-(2-{4-[(R)-(2-methyl-2H-tetrazol-5-yl)(phenyl)methyl]piperazine-1-carbonyl}pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide, ...
著者Kadam, R.U., Wilson, I.A.
登録日2018-02-14
公開日2019-02-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献An orally bioavailable small molecule fusion inhibitor of influenza virus
To Be Published
3DCQ
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LECB (PA-LII) IN COMPLEX WITH THE SYNTHETIC LIGAND 2G0
分子名称:Fucose-binding lectin PA-IIL, CALCIUM ION, (2S)-1-[(2S)-6-amino-2-({[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]acetyl}amino)hexanoyl]-N-[(1S)-1-carbamoyl-3-methylbutyl]pyrrolidine-2-carboxamide
著者Johansson, E.M., Crusz, S.A., Kolomiets, E., Buts, L., Kadam, R.U., Cacciarini, M., Bartels, K.M., Diggle, S.P., Camara, M., Williams, P., Loris, R., Nativi, C., Rosenau, F., Jaeger, K.E., Darbre, T., Reymond, J.L.
登録日2008-06-04
公開日2009-01-13
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB.
Chem.Biol., 15, 2008
3G23
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CRYSTAL STRUCTURE OF A LD-CARBOXYPEPTIDASE A (SARO_1426) FROM NOVOSPHINGOBIUM AROMATICIVORANS DSM AT 1.89 A RESOLUTION
分子名称:LD-carboxypeptidase A, SULFATE ION, GLYCEROL, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-01-30
公開日2009-02-10
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling.
J.Bacteriol., 195, 2013
4MWF
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3C
分子名称:Fab AR3C heavy chain, Fab AR3C light chain, Envelope glycoprotein E2, ...
著者Kong, L., Wilson, I.A., Law, M.
登録日2013-09-24
公開日2013-12-11
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Hepatitis C virus e2 envelope glycoprotein core structure.
Science, 342, 2013
4N0Y
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STRUCTURE OF THE HEPATITIS C ENVELOPE GLYCOPROTEIN E1 ANTIGENIC REGION 314-324 BOUND TO THE CROSS-NEUTRALIZING ANTIBODY IGH526
分子名称:IGH526 Heavy Chain, IGH526 Light Chain, HCV E1 peptide, ...
著者Kong, L., Wilson, I.A.
登録日2013-10-02
公開日2015-04-01
最終更新日2015-08-26
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.
J.Mol.Biol., 427, 2015