1H8N
| Three-dimensional structure of anti-ampicillin single chain Fv fragment from phage-displayed murine antibody libraries | Descriptor: | GLYCEROL, MUTANT AL2 6E7S9G, SULFATE ION | Authors: | Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-14 | Release date: | 2001-08-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The Importance of Framework Residues H6, H7 and H10 in Antibody Heavy Chains: Experimental Evidence for a New Structural Subclassification of Antibody V(H) Domains J.Mol.Biol., 309, 2001
|
|
2K35
| Hydramacin-1: Structure and antibacterial activity of a peptide from the basal metazoan Hydra | Descriptor: | hydramacin-1 | Authors: | Jung, S, Dingley, A.J, Stanisak, M, Gelhaus, C, Bosch, T, Podschun, R, Leippe, M, Gr tzinger, J. | Deposit date: | 2008-04-22 | Release date: | 2008-11-18 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Hydramacin-1, structure and antibacterial activity of a protein from the Basal metazoan hydra. J.Biol.Chem., 284, 2009
|
|
2LLR
| |
2LN8
| The solution structure of theromacin | Descriptor: | Theromacin | Authors: | Jung, S, Soennichsen, F.D, Hung, C.-W, Tholey, A, Boidin-Wichlacz, C, Hausgen, W, Gelhaus, C, Desel, C, Podschun, R, Watzig, V, Tasiemski, A, Leippe, M, Groetzinger, J. | Deposit date: | 2011-12-20 | Release date: | 2012-03-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities. J.Biol.Chem., 287, 2012
|
|
1I3G
| CRYSTAL STRUCTURE OF AN AMPICILLIN SINGLE CHAIN FV, FORM 1, FREE | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ANTIBODY FV FRAGMENT | Authors: | Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-15 | Release date: | 2001-10-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries. J.Mol.Biol., 309, 2001
|
|
2MXQ
| The solution structure of DEFA1, a highly potent antimicrobial peptide from the horse | Descriptor: | Paneth cell-specific alpha-defensin 1 | Authors: | Jung, S, Michalek, M, Shomali, M, Soennichsen, F.D. | Deposit date: | 2015-01-12 | Release date: | 2015-04-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure and functional studies of the highly potent equine antimicrobial peptide DEFA1. Biochem.Biophys.Res.Commun., 459, 2015
|
|
8JOQ
| |
8JOY
| Plk1 polo-box domain bound to HPV4 L2 residues 251-257 with pThr255 | Descriptor: | Peptide from Minor capsid protein L2, Serine/threonine-protein kinase PLK1 | Authors: | Ku, B, Jung, S. | Deposit date: | 2023-06-09 | Release date: | 2023-10-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Crystal Structures of Plk1 Polo-Box Domain Bound to the Human Papillomavirus Minor Capsid Protein L2-Derived Peptide. J.Microbiol, 61, 2023
|
|
7P1J
| Cryo EM structure of bison NHA2 in detergent structure | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1I
| Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1K
| Cryo EM structure of bison NHA2 in nano disc structure | Descriptor: | CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
6S5H
| Structure of the human RAB38 in complex with GTP | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Diaz-Saez, L, Jung, S, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Huber, K, Structural Genomics Consortium (SGC) | Deposit date: | 2019-07-01 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the human RAB38 in complex with GTP To Be Published
|
|
1H8S
| Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten. | Descriptor: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, MUTANT AL2 6E7P9G, SULFATE ION | Authors: | Burmester, J, Spinelli, S, Pugliese, L, Krebber, A, Honegger, A, Jung, S, Schimmele, B, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-15 | Release date: | 2001-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Selection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries J.Mol.Biol., 309, 2001
|
|
1H8O
| Three-dimensional structure of anti-ampicillin single chain Fv fragment. | Descriptor: | MUTANT AL2 6E7P9G, SULFATE ION | Authors: | Burmester, J, Spinelli, S, Pugliese, L, Krebber, A, Honegger, A, Jung, S, Schimmele, B, Cambillau, C, Pluckthun, A. | Deposit date: | 2001-02-14 | Release date: | 2001-08-02 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Selection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries J.Mol.Biol., 309, 2001
|
|
6Y7G
| Structure of the human RAB3C in complex with GDP | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Diaz-Saez, L, Jung, S, Raux, B, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Huber, K.V.M, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-29 | Release date: | 2021-03-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the human RAB3C in complex with GDP To Be Published
|
|
2M2F
| The membran-proximal domain of ADAM17 | Descriptor: | Disintegrin and metalloproteinase domain-containing protein 17 | Authors: | Duesterhoeft, S, Jung, S, Hung, C, Tholey, A, Soennichsen, F.D, Groetzinger, J, Lorenzen, I. | Deposit date: | 2012-12-20 | Release date: | 2013-04-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase. J.Am.Chem.Soc., 135, 2013
|
|
6S5F
| Structure of the human RAB39B in complex with GMPPNP | Descriptor: | 1,2-ETHANEDIOL, GLYCINE, MAGNESIUM ION, ... | Authors: | Diaz-Saez, L, Jung, S, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Huber, K, Structural Genomics Consortium (SGC) | Deposit date: | 2019-07-01 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the human RAB39B in complex with GMPPNP To Be Published
|
|
2LXO
| Identification of the Structural Traits Mediating the Antimicrobial Activity of a Chimeric Peptide of HBD2 and HBD3 | Descriptor: | Chimeric Peptide | Authors: | Spudy, B, Soennichsen, F.D, Waetzig, G.H, Grotzinger, J, Jung, S. | Deposit date: | 2012-08-30 | Release date: | 2013-08-14 | Last modified: | 2023-12-13 | Method: | SOLUTION NMR | Cite: | Identification of structural traits that increase the antimicrobial activity of a chimeric peptide of human beta-defensins 2 and 3. Biochem.Biophys.Res.Commun., 427, 2012
|
|
6GHG
| Variable heavy - variable light domain and Fab-arm CrossMabs with charged residue exchanges | Descriptor: | Fab heavy chain, Fab light chain, HEXAETHYLENE GLYCOL, ... | Authors: | Regula, J, Imhof-Jung, S, Molhoj, M, Benz, J, Ehler, A, Bujotzek, A, Schaefer, W, Klein, C. | Deposit date: | 2018-05-07 | Release date: | 2018-09-12 | Last modified: | 2018-12-05 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Variable heavy-variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly. Protein Eng. Des. Sel., 31, 2018
|
|
2N52
| |
1A26
| |
7APS
| The Fk1 domain of FKBP51 in complex with (2S)-2-((1S,5R,6R)-10-((3,5-dichlorophenyl)sulfonyl)-2-oxo-5-vinyl-3,10-diazabicyclo[4.3.1]decan-3-yl)propanoic acid | Descriptor: | (2~{S})-2-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]propanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Kolos, M.J, Pomplun, S, Riess, B, Purder, P, Voll, M.A, Merz, S, Bracher, A, Meyners, C, Krewald, V, Hausch, F. | Deposit date: | 2020-10-19 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.94 Å) | Cite: | Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chem Sci, 12, 2021
|
|
7APQ
| The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | Descriptor: | (1~{S},5~{S},6~{R})-10-(1,3-benzothiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Kolos, M.J, Pomplun, S, Riess, B, Purder, P, Voll, M.A, Merz, S, Bracher, A, Meyners, C, Krewald, V, Hausch, F. | Deposit date: | 2020-10-19 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chem Sci, 12, 2021
|
|
7APT
| The Fk1 domain of FKBP51 in complex with ((1S,5S,6R)-10-((3,5-dichlorophenyl)sulfonyl)-2-oxo-5-vinyl-3,10-diazabicyclo[4.3.1]decan-3-yl)acetic acid | Descriptor: | 2-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Kolos, M.J, Pomplun, S, Riess, B, Purder, P, Voll, M.A, Merz, S, Bracher, A, Meyners, C, Krewald, V, Hausch, F. | Deposit date: | 2020-10-19 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.131 Å) | Cite: | Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chem Sci, 12, 2021
|
|
7APW
| The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one | Descriptor: | (1S,5S,6R)-10-(benzo[d]thiazol-6-ylsulfonyl)-5-(methoxymethyl)-3-(pyridin-2-ylethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, Peptidyl-prolyl cis-trans isomerase FKBP5 | Authors: | Voll, A.M, Kolos, J.M, Pomplun, S, Riess, B, Purder, P, Merz, S, Bracher, A, Meyners, C, Krewald, V, Hausch, F. | Deposit date: | 2020-10-20 | Release date: | 2021-11-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chem Sci, 12, 2021
|
|