1D31
| THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Joshua-Tor, L, Frolow, F, Appella, E, Hope, H, Rabinovich, D, Sussman, J.L. | Deposit date: | 1991-04-25 | Release date: | 1992-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Three-dimensional structures of bulge-containing DNA fragments. J.Mol.Biol., 225, 1992
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1GCB
| GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL) | Descriptor: | GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ... | Authors: | Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C. | Deposit date: | 1995-07-18 | Release date: | 1995-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269, 1995
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1A6R
| GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A | Descriptor: | GAL6, SULFATE ION | Authors: | Joshua-Tor, L, Zheng, W, Johnston, S.A. | Deposit date: | 1998-02-27 | Release date: | 1998-10-21 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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3GCB
| GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454 | Descriptor: | GAL6, GLYCEROL, SULFATE ION | Authors: | Joshua-Tor, L, Zheng, W, Johnston, S.A. | Deposit date: | 1998-02-27 | Release date: | 1998-10-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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6X46
| NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) | Descriptor: | Gametocyte-specific factor 1, ZINC ION | Authors: | Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. | Deposit date: | 2020-05-22 | Release date: | 2021-03-03 | Last modified: | 2021-04-14 | Method: | SOLUTION NMR | Cite: | Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Rep, 34, 2021
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7UX9
| Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | Descriptor: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | Authors: | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | Deposit date: | 2022-05-05 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell, 186, 2023
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1CY5
| CRYSTAL STRUCTURE OF THE APAF-1 CARD | Descriptor: | BETA-MERCAPTOETHANOL, PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1), ZINC ION | Authors: | Vaughn, D.E, Joshua-Tor, L. | Deposit date: | 1999-08-31 | Release date: | 1999-09-13 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling. J.Mol.Biol., 293, 1999
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1CW9
| DNA DECAMER WITH AN ENGINEERED CROSSLINK IN THE MINOR GROOVE | Descriptor: | 5'-D(*CP*CP*AP*GP*(G47)P*CP*CP*TP*GP*G)-3', CALCIUM ION | Authors: | van Aalten, D.M.F, Erlanson, D.A, Verdine, G.L, Joshua-Tor, L. | Deposit date: | 1999-08-26 | Release date: | 1999-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A structural snapshot of base-pair opening in DNA. Proc.Natl.Acad.Sci.USA, 96, 1999
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1D7E
| CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN | Descriptor: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | Authors: | Van Aalten, D.M.F, Crielaard, W, Hellingwerf, K.J, Joshua-Tor, L. | Deposit date: | 1999-10-17 | Release date: | 2000-03-31 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility. Protein Sci., 9, 2000
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1CP2
| NITROGENASE IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM | Descriptor: | IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN | Authors: | Schlessman, J.L, Woo, D, Joshua-Tor, L, Howard, J.B, Rees, D.C. | Deposit date: | 1998-05-11 | Release date: | 1998-11-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum. J.Mol.Biol., 280, 1998
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4F3T
| Human Argonaute-2 - miR-20a complex | Descriptor: | PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3') | Authors: | Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L. | Deposit date: | 2012-05-09 | Release date: | 2012-05-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Structure of Human Argonaute-2 in Complex with miR-20a. Cell(Cambridge,Mass.), 150, 2012
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2GXA
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8E27
| RNA-free Human Dis3L2 | Descriptor: | DIS3-like exonuclease 2 | Authors: | Meze, K, Thomas, D.R, Joshua-Tor, L. | Deposit date: | 2022-08-14 | Release date: | 2023-03-01 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A shape-shifting nuclease unravels structured RNA. Nat.Struct.Mol.Biol., 30, 2023
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8E2A
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8E28
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8E29
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1CAD
| X-RAY CRYSTAL STRUCTURES OF THE OXIDIZED AND REDUCED FORMS OF THE RUBREDOXIN FROM THE MARINE HYPERTHERMOPHILIC ARCHAEBACTERIUM PYROCOCCUS FURIOSUS | Descriptor: | FE (III) ION, RUBREDOXIN | Authors: | Day, M.W, Hsu, B.T, Joshua-Tor, L, Park, J.B, Zhou, Z.H, Adams, M.W.W, Rees, D.C. | Deposit date: | 1992-05-18 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Sci., 1, 1992
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1CAA
| X-RAY CRYSTAL STRUCTURES OF THE OXIDIZED AND REDUCED FORMS OF THE RUBREDOXIN FROM THE MARINE HYPERTHERMOPHILIC ARCHAEBACTERIUM PYROCOCCUS FURIOSUS | Descriptor: | FE (III) ION, RUBREDOXIN | Authors: | Day, M.W, Hsu, B.T, Joshua-Tor, L, Park, J.B, Zhou, Z.H, Adams, M.W.W, Rees, D.C. | Deposit date: | 1992-05-18 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Sci., 1, 1992
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1CB5
| HUMAN BLEOMYCIN HYDROLASE. | Descriptor: | BLEOMYCIN HYDROLASE | Authors: | O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L. | Deposit date: | 1999-03-01 | Release date: | 2000-03-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure Fold.Des., 7, 1999
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1R6Z
| The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) | Descriptor: | Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2003-10-17 | Release date: | 2004-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat.Struct.Biol., 10, 2003
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1R9W
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4O9D
| Structure of Dos1 propeller | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Rik1-associated factor 1 | Authors: | Kuscu, C, Schalch, T, Joshua-Tor, L. | Deposit date: | 2014-01-02 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Proc.Natl.Acad.Sci.USA, 111, 2014
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4PMW
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3TIX
| Crystal structure of the Chp1-Tas3 complex core | Descriptor: | CHLORIDE ION, Chromo domain-containing protein 1, POTASSIUM ION, ... | Authors: | Schalch, T, Joshua-Tor, L. | Deposit date: | 2011-08-22 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9001 Å) | Cite: | The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nat.Struct.Mol.Biol., 18, 2011
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3V2U
| Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Galactose/lactose metabolism regulatory protein GAL80, ... | Authors: | Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. | Deposit date: | 2011-12-12 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes Dev., 26, 2012
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