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1D31
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THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS
Descriptor:DNA (5'-D(*CP*GP*CP*AP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Joshua-Tor, L., Frolow, F., Appella, E., Hope, H., Rabinovich, D., Sussman, J.L.
Deposit date:1991-04-25
Release date:1992-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structures of bulge-containing DNA fragments.
J.Mol.Biol., 225, 1992
1GCB
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GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL)
Descriptor:GAL6 HG (EMTS) DERIVATIVE, SULFATE ION, MERCURY (II) ION, ...
Authors:Joshua-Tor, L., Xu, H.E., Johnston, S.A., Rees, D.C.
Deposit date:1995-07-18
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6.
Science, 269, 1995
1A6R
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GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A
Descriptor:GAL6, SULFATE ION
Authors:Joshua-Tor, L., Zheng, W., Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
3GCB
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GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454
Descriptor:GAL6, SULFATE ION, GLYCEROL
Authors:Joshua-Tor, L., Zheng, W., Johnston, S.A.
Deposit date:1998-02-27
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase.
Cell(Cambridge,Mass.), 93, 1998
1CAA
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X-RAY CRYSTAL STRUCTURES OF THE OXIDIZED AND REDUCED FORMS OF THE RUBREDOXIN FROM THE MARINE HYPERTHERMOPHILIC ARCHAEBACTERIUM PYROCOCCUS FURIOSUS
Descriptor:RUBREDOXIN, FE (III) ION
Authors:Day, M.W., Hsu, B.T., Joshua-Tor, L., Park, J.B., Zhou, Z.H., Adams, M.W.W., Rees, D.C.
Deposit date:1992-05-18
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus.
Protein Sci., 1, 1992
1CAD
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X-RAY CRYSTAL STRUCTURES OF THE OXIDIZED AND REDUCED FORMS OF THE RUBREDOXIN FROM THE MARINE HYPERTHERMOPHILIC ARCHAEBACTERIUM PYROCOCCUS FURIOSUS
Descriptor:RUBREDOXIN, FE (III) ION
Authors:Day, M.W., Hsu, B.T., Joshua-Tor, L., Park, J.B., Zhou, Z.H., Adams, M.W.W., Rees, D.C.
Deposit date:1992-05-18
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus.
Protein Sci., 1, 1992
1CB5
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HUMAN BLEOMYCIN HYDROLASE.
Descriptor:BLEOMYCIN HYDROLASE
Authors:O'Farrell, P.A., Gonzalez, F., Zheng, W., Johnston, S.A., Joshua-Tor, L.
Deposit date:1999-03-01
Release date:2000-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease.
Structure Fold.Des., 7, 1999
1CP2
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NITROGENASE IRON PROTEIN FROM CLOSTRIDIUM PASTEURIANUM
Descriptor:NITROGENASE IRON PROTEIN, IRON/SULFUR CLUSTER
Authors:Schlessman, J.L., Woo, D., Joshua-Tor, L., Howard, J.B., Rees, D.C.
Deposit date:1998-05-11
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum.
J.Mol.Biol., 280, 1998
1CW9
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DNA DECAMER WITH AN ENGINEERED CROSSLINK IN THE MINOR GROOVE
Descriptor:5'-D(*CP*CP*AP*GP*(G47)P*CP*CP*TP*GP*G)-3', CALCIUM ION
Authors:van Aalten, D.M.F., Erlanson, D.A., Verdine, G.L., Joshua-Tor, L.
Deposit date:1999-08-26
Release date:1999-10-14
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A structural snapshot of base-pair opening in DNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CY5
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CRYSTAL STRUCTURE OF THE APAF-1 CARD
Descriptor:PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1), ZINC ION, BETA-MERCAPTOETHANOL
Authors:Vaughn, D.E., Joshua-Tor, L.
Deposit date:1999-08-31
Release date:1999-09-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.
J.Mol.Biol., 293, 1999
1D7E
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:1999-10-17
Release date:2000-03-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Conformational substates in different crystal forms of the photoactive yellow protein--correlation with theoretical and experimental flexibility.
Protein Sci., 9, 2000
1F08
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CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN E1 FROM PAPILLOMAVIRUS
Descriptor:REPLICATION PROTEIN E1, BROMIDE ION
Authors:Enemark, E.J., Chen, G., Vaughn, D.E., Stenlund, A., Joshua-Tor, L.
Deposit date:2000-05-15
Release date:2001-05-16
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus.
Mol.Cell, 6, 2000
1F57
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CARBOXYPEPTIDASE A COMPLEX WITH D-CYSTEINE AT 1.75 A
Descriptor:CARBOXYPEPTIDASE A, ZINC ION, D-CYSTEINE
Authors:van Aalten, D.M., Chong, C.R., Joshua-Tor, L.
Deposit date:2000-06-13
Release date:2000-09-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
Biochemistry, 39, 2000
1GSV
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-08
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSW
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G51S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1GSX
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CRYSTAL STRUCTURE OF THE P65 CRYSTAL FORM OF PHOTOACTIVE YELLOW PROTEIN G47S/G51S MUTANT
Descriptor:PHOTOACTIVE YELLOW PROTEIN, 4'-HYDROXYCINNAMIC ACID
Authors:Van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2002-01-09
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Engineering Photocycle Dynamics: Crystal Structures and Kinetics of Three Photoactive Yellow Protein Hinge-Bending Mutants
J.Biol.Chem., 227, 2002
1KOU
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CRYSTAL STRUCTURE OF THE PHOTOACTIVE YELLOW PROTEIN RECONSTITUTED WITH CAFFEIC ACID AT 1.16 A RESOLUTION
Descriptor:PHOTOACTIVE YELLOW PROTEIN, CAFFEIC ACID, N-BUTANE
Authors:van Aalten, D.M.F., Crielaard, W., Hellingwerf, K.J., Joshua-Tor, L.
Deposit date:2001-12-22
Release date:2002-04-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1KQJ
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CRYSTAL STRUCTURE OF A MUTANT OF MUTY CATALYTIC DOMAIN
Descriptor:A/G-SPECIFIC ADENINE GLYCOSYLASE, SULFATE ION, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E., Chmiel, N.H., Golinelli, M.P., David, S.S., Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
1KSX
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CRYSTAL STRUCTURES OF TWO INTERMEDIATES IN THE ASSEMBLY OF THE PAPILLOMAVIRUS REPLICATION INITIATION COMPLEX
Descriptor:E1 Recognition Sequence, REPLICATION PROTEIN E1
Authors:Enemark, E.J., Stenlund, A., Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
1KSY
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CRYSTAL STRUCTURES OF TWO INTERMEDIATES IN THE ASSEMBLY OF THE PAPILLOMAVIRUS REPLICATION INITIATION COMPLEX
Descriptor:E1 Recognition Sequence, Strand 1, Strand 2, ...
Authors:Enemark, E.J., Stenlund, A., Joshua-Tor, L.
Deposit date:2002-01-14
Release date:2002-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex.
EMBO J., 21, 2002
1R6Z
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THE CRYSTAL STRUCTURE OF THE ARGONAUTE2 PAZ DOMAIN (AS A MBP FUSION)
Descriptor:Chimera of Maltose-binding periplasmic protein and Argonaute 2, MALTOSE, NICKEL (II) ION
Authors:Song, J.J., Liu, J., Tolia, N.H., Schneiderman, J., Smith, S.K., Martienssen, R.A., Hannon, G.J., Joshua-Tor, L.
Deposit date:2003-10-17
Release date:2004-01-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.
Nat.Struct.Biol., 10, 2003
1R9W
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CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF THE HUMAN PAPILLOMAVIRUS TYPE 18 (HPV-18) REPLICATION INITIATION PROTEIN E1
Descriptor:Replication protein E1
Authors:Auster, A.S., Joshua-Tor, L.
Deposit date:2003-10-31
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding.
J.Biol.Chem., 279, 2004
1U04
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CRYSTAL STRUCTURE OF FULL LENGTH ARGONAUTE FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein PF0537
Authors:Song, J.J., Smith, S.K., Hannon, G.J., Joshua-Tor, L.
Deposit date:2004-07-12
Release date:2004-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
Science, 305, 2004
1Z25
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STRUCTURE OF P.FURIOSUS ARGONAUTE WITH BOUND MN2+
Descriptor:Argonaute, MANGANESE (II) ION
Authors:Rivas, F.V., Tolia, N.H., Song, J.J., Aragon, J.P., Liu, J., Hannon, G.J., Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
1Z26
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STRUCTURE OF PYROCOCCUS FURIOSUS ARGONAUTE WITH BOUND TUNGSTATE
Descriptor:Argonaute, TUNGSTATE(VI)ION
Authors:Rivas, F.V., Tolia, N.H., Song, J.J., Aragon, J.P., Liu, J., Hannon, G.J., Joshua-Tor, L.
Deposit date:2005-03-07
Release date:2005-04-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005