Author results

1H8B
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EF-HANDS 3,4 FROM ALPHA-ACTININ / Z-REPEAT 7 FROM TITIN
Descriptor:ALPHA-ACTININ 2, SKELETAL MUSCLE ISOFORM, TITIN
Authors:Atkinson, R.A., Joseph, C., Kelly, G., Muskett, F.W., Frenkiel, T.A., Nietlispach, D., Pastore, A.
Deposit date:2001-02-01
Release date:2001-08-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Ca2+-Independent Binding of an EF-Hand Domain to a Novel Motif in the Alpha-Actinin-Titin Complex
Nat.Struct.Biol., 8, 2001
1VIG
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NMR STUDY OF VIGILIN, REPEAT 6, 40 STRUCTURES
Descriptor:VIGILIN
Authors:Musco, G., Stier, G., Joseph, C., Morelli, M.A.C., Nilges, M., Gibson, T.J., Pastore, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Cell(Cambridge,Mass.), 85, 1996
1VIH
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NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE
Descriptor:VIGILIN
Authors:Musco, G., Stier, G., Joseph, C., Morelli, M.A.C., Nilges, M., Gibson, T.J., Pastore, A.
Deposit date:1995-11-29
Release date:1996-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndrome.
Cell(Cambridge,Mass.), 85, 1996
5PZQ
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 2-(4-METHOXYPHENYL)FURAN-3,4-DICARBOXYLIC ACID
Descriptor:Fructose-1,6-bisphosphatase 1, 2-(4-methoxyphenyl)furan-3,4-dicarboxylic acid
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-16
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 2-(4-methoxyphenyl)furan-3,4-dicarboxylic acid
To be published
5PZR
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(3-CHLOROPHENYL)SULFONYL-3-[3-[3-[(3-CHLOROPHENYL)SULFONYLCARBAMOYLAMINO]PROPOXY]PROPYL]UREA
Descriptor:Fructose-1,6-bisphosphatase 1, N,N'-{oxybis[(propane-3,1-diyl)carbamoyl]}bis(3-chlorobenzene-1-sulfonamide)
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-11
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[3-[3-[(3-chlorophenyl)sulfonylcarbamoylamino]propoxy]propyl]urea
To be published
5PZS
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(3-CHLOROPHENYL)SULFONYL-3-[6-[(3-CHLOROPHENYL)SULFONYLCARBAMOYLAMINO]HEXYL]UREA
Descriptor:Fructose-1,6-bisphosphatase 1, N,N'-(hexane-1,6-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide)
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-11
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.368 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[6-[(3-chlorophenyl)sulfonylcarbamoylamino]hexyl]urea
To be published
5PZT
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-(3-ETHYL-4-PHENYLPHENYL)SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-2-ethyl[1,1'-biphenyl]-4-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(3-ethyl-4-phenylphenyl)sulfonylurea
To be published
5PZU
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR [5-[2-AMINO-5-(2-METHYLPROPYL)-1,3-THIAZOL-4-YL]FURAN-2-YL]PHOSPHONIC ACID
Descriptor:Fructose-1,6-bisphosphatase 1, {5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}phosphonic acid
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor [5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
To be published
5PZV
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(4-BROMOPYRIDIN-2-YL)-3-(4-CHLOROPHENYL)SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(4-bromopyridin-2-yl)carbamoyl]-4-chlorobenzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-11
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromopyridin-2-yl)-3-(4-chlorophenyl)sulfonylurea
To be published
5PZW
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(3-CHLOROPHENYL)SULFONYL-3-[5-[(3-CHLOROPHENYL)SULFONYLCARBAMOYLAMINO]PENTYL]UREA
Descriptor:Fructose-1,6-bisphosphatase 1, N,N'-(pentane-1,5-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide), AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-16
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(3-chlorophenyl)sulfonyl-3-[5-[(3-chlorophenyl)sulfonylcarbamoylamino]pentyl]urea
To be published
5PZX
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[4-METHOXY-3-(2-METHYLPROPYL)PHENYL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-methoxy-3-(2-methylpropyl)benzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-methoxy-3-(2-methylpropyl)phenyl]sulfonylurea
To be published
5PZY
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-(2-CHLOROPHENYL)SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-2-chlorobenzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(2-chlorophenyl)sulfonylurea
To be published
5PZZ
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-(3,4-DICHLOROPHENYL)SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3,4-dichlorobenzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-28
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(3,4-dichlorophenyl)sulfonylurea
To be published
5Q00
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 2-[3-[(5-BROMO-1,3-THIAZOL-2-YL)CARBAMOYLSULFAMOYL]-1-METHYLINDOL-7-YL]OXYACETAMIDE
Descriptor:Fructose-1,6-bisphosphatase 1, 2-[(3-{[(5-bromo-1,3-thiazol-2-yl)carbamoyl]sulfamoyl}-1-methyl-1H-indol-7-yl)oxy]acetamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-16
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 2-[3-[(5-bromo-1,3-thiazol-2-yl)carbamoylsulfamoyl]-1-methylindol-7-yl]oxyacetamide
To be published
5Q01
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[4-(4,5-DICHLORO-2-METHYLPYRAZOL-3-YL)OXYPHENYL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-[(3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy]benzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea
To be published
5Q02
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[5-(1,2-OXAZOL-3-YL)THIOPHEN-2-YL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(1,2-oxazol-3-yl)thiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.095 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(1,2-oxazol-3-yl)thiophen-2-yl]sulfonylurea
To be published
5Q03
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[5-(2-METHYLPROPYL)THIOPHEN-2-YL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(2-methylpropyl)thiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(2-methylpropyl)thiophen-2-yl]sulfonylurea
To be published
5Q04
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(4-BROMO-5-CHLOROTHIOPHEN-2-YL)SULFONYL-3-(5-BROMO-1,3-THIAZOL-2-YL)UREA
Descriptor:Fructose-1,6-bisphosphatase 1, 4-bromo-N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-chlorothiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromo-5-chlorothiophen-2-yl)sulfonyl-3-(5-bromo-1,3-thiazol-2-yl)urea
To be published
5Q05
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[5-(2-METHOXYETHYL)-4-METHYLTHIOPHEN-2-YL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-20
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylurea
To be published
5Q06
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-BROMO-1,3-THIAZOL-2-YL)-3-[4-(2-METHYL-1,3-THIAZOL-4-YL)PHENYL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-4-(2-methyl-1,3-thiazol-4-yl)benzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]sulfonylurea
To be published
5Q07
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(4-BROMO-6-MORPHOLIN-4-YLPYRIDIN-2-YL)-3-[5-(2-METHOXYETHYL)-4-METHYLTHIOPHEN-2-YL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-{[4-bromo-6-(morpholin-4-yl)pyridin-2-yl]carbamoyl}-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-16
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.424 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromo-6-morpholin-4-ylpyridin-2-yl)-3-[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylurea
To be published
5Q08
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(1-BENZOTHIOPHEN-3-YLSULFONYL)-3-(5-BROMO-1,3-THIAZOL-2-YL)UREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-1-benzothiophene-3-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(1-benzothiophen-3-ylsulfonyl)-3-(5-bromo-1,3-thiazol-2-yl)urea
To be published
5Q09
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-[4-BROMO-6-(CARBAMOYLAMINO)PYRIDIN-2-YL]-3-[5-(2-METHOXYETHYL)-4-METHYLTHIOPHEN-2-YL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-{[4-bromo-6-(carbamoylamino)pyridin-2-yl]carbamoyl}-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-16
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-[4-bromo-6-(carbamoylamino)pyridin-2-yl]-3-[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylurea
To be published
5Q0A
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(5-CYANOPYRAZIN-2-YL)-3-[3-(DIFLUOROMETHOXY)PHENYL]SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(5-cyanopyrazin-2-yl)carbamoyl]-3-(difluoromethoxy)benzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-11
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-cyanopyrazin-2-yl)-3-[3-(difluoromethoxy)phenyl]sulfonylurea
To be published
5Q0B
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HUMAN LIVER FRUCTOSE-1,6-BISPHOSPHATASE 1 (FRUCTOSE 1,6-BISPHOSPHATE 1-PHOSPHATASE, E.C.3.1.3.11) COMPLEXED WITH THE ALLOSTERIC INHIBITOR 1-(4-BROMO-3-METHYL-1,2-THIAZOL-5-YL)-3-(3-METHYLPHENYL)SULFONYLUREA
Descriptor:Fructose-1,6-bisphosphatase 1, N-[(4-bromo-3-methyl-1,2-thiazol-5-yl)carbamoyl]-3-methylbenzene-1-sulfonamide
Authors:Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Deposit date:2017-04-18
Release date:2019-01-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromo-3-methyl-1,2-thiazol-5-yl)-3-(3-methylphenyl)sulfonylurea
To be published