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5ONI
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LOW-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR 4P
分子名称:Casein kinase II subunit alpha, 4-(3-methylbut-2-enoxy)-5-propan-2-yl-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, SULFATE ION, ...
著者Hochscherf, J., Lindenblatt, D., Witulski, B., Birus, R., Aichele, D., Marminon, C., Bouaziz, Z., Le Borgne, M., Jose, J., Niefind, K.
登録日2017-08-03
公開日2017-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '.
Pharmaceuticals (Basel), 10, 2017
5OOI
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STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA') IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR 4P
分子名称:Casein kinase II subunit alpha', 4-(3-methylbut-2-enoxy)-5-propan-2-yl-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, 1,2-ETHANEDIOL, ...
著者Hochscherf, J., Lindenblatt, D., Witulski, B., Birus, R., Aichele, D., Marminon, C., Bouaziz, Z., Le Borgne, M., Jose, J., Niefind, K.
登録日2017-08-07
公開日2017-12-27
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '.
Pharmaceuticals (Basel), 10, 2017
6HBN
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HIGH-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA/CSKN2A1 GENE PRODUCT) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR THN27
分子名称:Casein kinase II subunit alpha, CHLORIDE ION, 5-propan-2-yl-4-prop-2-enoxy-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, ...
著者Niefind, K., Hochscherf, J., Dimper, V., Witulski, B., Lindenblatt, D., Jose, J., Le Borgne, M.
登録日2018-08-10
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
6HMB
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STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR CX-4945 (SILMITASERTIB)
分子名称:Casein kinase II subunit alpha', 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Niefind, K., Lindenblatt, D., Applegate, V.M., Jose, J., Le Borgne, M.
登録日2018-09-12
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
6HMC
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STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR THN27
分子名称:Casein kinase II subunit alpha', 1,2-ETHANEDIOL, 5-propan-2-yl-4-prop-2-enoxy-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione
著者Niefind, K., Lindenblatt, D., Dimper, V., Jose, J., Le Borgne, M.
登録日2018-09-12
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
6HMD
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STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR AR18
分子名称:Casein kinase II subunit alpha', 1,2-ETHANEDIOL, 5-[2-(diethylamino)ethyl]-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, ...
著者Niefind, K., Lindenblatt, D., Jose, J., Le Borgne, M.
登録日2018-09-12
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
6HME
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LOW-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA; CSNK2A1 GENE PRODUCT) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR THN27
分子名称:Casein kinase II subunit alpha, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Niefind, K., Lindenblatt, D., Jose, J., Le Borgne, M.
登録日2018-09-12
公開日2019-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
6HMQ
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STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE BENZOTRIAZOLE-TYPE INHIBITOR MB002
分子名称:Casein kinase II subunit alpha', 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 1,2-ETHANEDIOL, ...
著者Niefind, K., Lindenblatt, D., Applegate, V.M., Jose, J., Le Borgne, M.
登録日2018-09-12
公開日2019-03-27
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Diacritic Binding of an Indenoindole Inhibitor by CK2alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2alpha' Structures
Acs Omega, 2019
5N9K
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CRYSTAL STRUCTURE OF HUMAN PROTEIN KINASE CK2 CATALYTIC SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE, TIGHT-BINDING DIBENZOFURAN INHIBITOR TF107 (5)
分子名称:Casein kinase II subunit alpha, 1,3-bis(chloranyl)-6-[(~{E})-(4-methoxyphenyl)iminomethyl]dibenzofuran-2,7-diol, ACETATE ION, ...
著者Schnitzler, A., Gratz, A., Bollacke, A., Weyrich, M., Kucklaender, U., Wuensch, B., Goetz, C., Niefind, K., Jose, J.
登録日2017-02-25
公開日2018-02-28
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.643 Å)
主引用文献A pi-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors.
Pharmaceuticals, 11, 2018
5N9L
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CRYSTAL STRUCTURE OF HUMAN PROTEIN KINASE CK2 CATALYTIC SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE DIBENZOFURAN INHIBITOR TF (4B)
分子名称:Casein kinase II subunit alpha, (4~{Z})-6,7-bis(chloranyl)-4-[[(4-methylphenyl)amino]methylidene]-8-oxidanyl-1,2-dihydrodibenzofuran-3-one, ACETATE ION, ...
著者Schnitzler, A., Gratz, A., Bollacke, A., Weyrich, M., Kucklaender, U., Wuensch, B., Goetz, C., Niefind, K., Jose, J.
登録日2017-02-25
公開日2018-02-28
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A pi-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors.
Pharmaceuticals, 11, 2018
5N9N
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CRYSTAL STRUCTURE OF HUMAN PROTEIN KINASE CK2 CATALYTIC SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE, TIGHT-BINDING DIBENZOFURAN INHIBITOR TF85 (4A)
分子名称:Casein kinase II subunit alpha, (4~{Z})-7,9-bis(chloranyl)-4-[[(4-methoxyphenyl)amino]methylidene]-8-oxidanyl-1,2-dihydrodibenzofuran-3-one, ACETATE ION, ...
著者Schnitzler, A., Gratz, A., Bollacke, A., Weyrich, M., Kucklaender, U., Wuensch, B., Goetz, C., Niefind, K., Jose, J.
登録日2017-02-25
公開日2018-02-28
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.841 Å)
主引用文献A pi-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors.
Pharmaceuticals, 11, 2018
4IB5
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STRUCTURE OF HUMAN PROTEIN KINASE CK2 CATALYTIC SUBUNIT IN COMPLEX WITH A CK2BETA-COMPETITIVE CYCLIC PEPTIDE
分子名称:Casein kinase II subunit alpha, CK2beta-derived cyclic peptide, GLYCEROL, ...
著者Raaf, J., Guerra, B., Neundorf, I., Bopp, B., Issinger, O.-G., Jose, J., Pietsch, M., Niefind, K.
登録日2012-12-08
公開日2013-03-20
最終更新日2013-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献First structure of protein kinase CK2 catalytic subunit with an effective CK2 beta-competitive ligand
Acs Chem.Biol., 8, 2013
3J0F
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SINDBIS VIRION
分子名称:Capsid protein, E1 envelope glycoprotein, E2 envelope glycoprotein
著者Tang, J., Jose, J., Zhang, W., Chipman, P., Kuhn, R.J., Baker, T.S.
登録日2011-07-08
公開日2011-10-12
最終更新日2012-05-30
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Molecular Links between the E2 Envelope Glycoprotein and Nucleocapsid Core in Sindbis Virus.
J.Mol.Biol., 414, 2011
4UOK
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ELECTRON CRYO-MICROSCOPY OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS TC-83 IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB 3B4C-4
分子名称:FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN
著者Porta, J., Jose, J., Roehrig, J.T., Blair, C.D., Kuhn, R.J., Rossmann, M.G.
登録日2014-06-04
公開日2014-09-17
最終更新日2019-05-29
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.
J.Virol., 88, 2014
4UOM
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ELECTRON CRYO-MICROSCOPY OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS TC- 83 IN COMPLEX WITH NEUTRALIZING ANTIBODY FAB F5
分子名称:FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN
著者Porta, J., Jose, J., Roehrig, J.T., Blair, C.D., Kuhn, R.J., Rossmann, M.G.
登録日2014-06-05
公開日2014-10-15
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies.
J.Virol., 88, 2014
5OMY
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HIGH-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR 4P
分子名称:Casein kinase II subunit alpha, 4-(3-methylbut-2-enoxy)-5-propan-2-yl-7,8-dihydro-6~{H}-indeno[1,2-b]indole-9,10-dione, CHLORIDE ION
著者Hochscherf, J., Lindenblatt, D., Witulski, B., Birus, R., Aichele, D., Marminon, C., Bouaziz, Z., Le Borgne, M., Jose, J., Niefind, K.
登録日2017-08-02
公開日2017-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '.
Pharmaceuticals (Basel), 10, 2017
3MUU
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CRYSTAL STRUCTURE OF THE SINDBIS VIRUS E2-E1 HETERODIMER AT LOW PH
分子名称:Structural polyprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Li, L., Jose, J., Xiang, Y., Kuhn, R.J., Rossmann, M.G.
登録日2010-05-03
公開日2010-11-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structural changes of envelope proteins during alphavirus fusion.
Nature, 468, 2010
3MUW
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PSEUDO-ATOMIC STRUCTURE OF THE E2-E1 PROTEIN SHELL IN SINDBIS VIRUS
分子名称:Structural polyprotein
著者Li, L., Jose, J., Xiang, Y., Kuhn, R.J., Rossmann, M.G.
登録日2010-05-03
公開日2010-11-24
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structural changes of envelope proteins during alphavirus fusion.
Nature, 468, 2010
4MEE
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CRYSTAL STRUCTURE OF THE TRANSPORT UNIT OF THE AUTOTRANSPORTER AIDA-I FROM ESCHERICHIA COLI
分子名称:Diffuse adherence adhesin
著者Gawarzewski, I., Tschapek, B., Hoeppner, A., Smits, S.H., Jose, J., Schmitt, L.
登録日2013-08-26
公開日2014-06-04
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the transport unit of the autotransporter adhesin involved in diffuse adherence from Escherichia coli.
J.Struct.Biol., 187, 2014
4O6B
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DENGUE TYPE2 VIRUS NON-STRUCTURAL PROTEIN 1 (NS1) FORM 1 CRYSTAL
分子名称:Non-structural protein 1, N-ACETYL-D-GLUCOSAMINE
著者Akey, D.L., Smith, J.L.
登録日2013-12-20
公開日2014-02-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.0005 Å)
主引用文献Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.
Science, 343, 2014
4O6C
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WEST NILE VIRUS NON-STRUCTURAL PROTEIN 1 (NS1) FORM 2 CRYSTAL
分子名称:NS1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
著者Akey, D.L., Smith, J.L.
登録日2013-12-20
公開日2014-02-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.7508 Å)
主引用文献Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.
Science, 343, 2014
4O6D
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WEST NILE VIRUS NON-STRUCTURAL PROTEIN 1 (NS1) FORM 1 CRYSTAL
分子名称:NS1, N-ACETYL-D-GLUCOSAMINE, OXTOXYNOL-10, ...
著者Akey, D.L., Smith, J.L.
登録日2013-12-20
公開日2014-02-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.5936 Å)
主引用文献Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.
Science, 343, 2014
3N40
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CRYSTAL STRUCTURE OF THE IMMATURE ENVELOPE GLYCOPROTEIN COMPLEX OF CHIKUNGUNYA VIRUS.
分子名称:P62 envelope glycoprotein, E1 envelope glycoprotein, N-ACETYL-D-GLUCOSAMINE, ...
著者Voss, J., Vaney, M.C., Duquerroy, S., Rey, F.A.
登録日2010-05-21
公開日2010-12-01
最終更新日2012-04-11
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography.
Nature, 468, 2010
3N41
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CRYSTAL STRUCTURE OF THE MATURE ENVELOPE GLYCOPROTEIN COMPLEX (SPONTANEOUS CLEAVAGE) OF CHIKUNGUNYA VIRUS.
分子名称:E3 envelope glycoprotein, E2 envelope glycoprotein, E1 envelope glycoprotein, ...
著者Voss, J., Vaney, M.C., Duquerroy, S., Rey, F.A.
登録日2010-05-21
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography.
Nature, 468, 2010
3N42
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CRYSTAL STRUCTURES OF THE MATURE ENVELOPE GLYCOPROTEIN COMPLEX (FURIN CLEAVAGE) OF CHIKUNGUNYA VIRUS.
分子名称:E3 envelope glycoprotein, E2 envelope glycoprotein, E1 envelope glycoprotein, ...
著者Voss, J., Vaney, M.C., Duquerroy, S., Rey, F.A.
登録日2010-05-21
公開日2010-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography.
Nature, 468, 2010
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