Author results

2VKZ
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STRUCTURE OF THE CERULENIN-INHIBITED FUNGAL FATTY ACID SYNTHASE TYPE I MULTIENZYME COMPLEX
分子名称:FATTY ACID SYNTHASE SUBUNIT ALPHA, FATTY ACID SYNTHASE SUBUNIT BETA, (2S, ...
著者Johansson, P., Wiltschi, B., Kumari, P., Kessler, B., Vonrhein, C., Vonck, J., Oesterhelt, D., Grininger, M.
登録日2008-01-07
公開日2008-08-12
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex.
Proc.Natl.Acad.Sci.USA, 105, 2008
4AJD
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IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF PDE10 FRAGMENT INHIBITORS
分子名称:CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, PDE10, ...
著者Johansson, P., Albert, J.S., Spadola, L., Akerud, T., Back, E., Hillertz, P., Horsefeld, R., Scott, C., Spear, N., Tian, G., Tigerstrom, A., Aharony, D., Geschwindner, S.
登録日2012-02-16
公開日2013-03-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification and Structural Characterization of Pde10 Fragment Inhibitors
To be Published
4AJF
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IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF PDE10 FRAGMENT INHIBITORS
分子名称:CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ZINC ION, ...
著者Johansson, P., Albert, J.S., Spadola, L., Akerud, T., Back, E., Hillertz, P., Horsefeld, R., Scott, C., Spear, N., Tian, G., Tigerstrom, A., Aharony, D., Geschwindner, S.
登録日2012-02-16
公開日2013-03-06
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification and Structural Characterization of Pde10 Fragment Inhibitors
To be Published
4AJG
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IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF PDE10 FRAGMENT INHIBITORS
分子名称:CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ZINC ION, ...
著者Johansson, P., Albert, J.S., Spadola, L., Akerud, T., Back, E., Hillertz, P., Horsefeld, R., Scott, C., Spear, N., Tian, G., Tigerstrom, A., Aharony, D., Geschwindner, S.
登録日2012-02-16
公開日2013-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification and Structural Characterization of Pde10 Fragment Inhibitors
To be Published
6EJ2
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BACE1 COMPOUND 28
分子名称:Beta-secretase 1, compound 28
著者Johansson, P.
登録日2017-09-20
公開日2018-04-18
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Toward beta-Secretase-1 Inhibitors with Improved Isoform Selectivity.
J. Med. Chem., 61, 2018
6EJ3
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BACE1 COMPOUND 23
分子名称:Beta-secretase 1, (1r,4r)-4-methoxy-6'-(5-methyl-3-pyridinyl)-3'H-dispiro[cyclohexane-1,2'-indene-1',4''-[1,3]oxazol]-2''-amine
著者Johansson, P.
登録日2017-09-20
公開日2018-04-18
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Toward beta-Secretase-1 Inhibitors with Improved Isoform Selectivity.
J. Med. Chem., 61, 2018
1UMZ
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XYLOGLUCAN ENDOTRANSGLYCOSYLASE IN COMPLEX WITH THE XYLOGLUCAN NONASACCHARIDE XLLG.
分子名称:XYLOGLUCAN ENDOTRANSGLYCOSYLASE, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Johansson, P., Brumer, H., Kallas, A.M., Henriksson, H., Denman, S.E., Teeri, T.T., Jones, T.A.
登録日2003-09-03
公開日2004-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of a Poplar Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding
Plant Cell, 16, 2004
1UN1
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XYLOGLUCAN ENDOTRANSGLYCOSYLASE NATIVE STRUCTURE.
分子名称:XYLOGLUCAN ENDOTRANSGLYCOSYLASE, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Johansson, P., Brumer, H., Kallas, A., Henriksson, H., Denman, S., Teeri, T.T., Jones, T.A.
登録日2003-09-03
公開日2004-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of a Poplar Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding
Plant Cell, 16, 2004
2BNG
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STRUCTURE OF AN M.TUBERCULOSIS LEH-LIKE EPOXIDE HYDROLASE
分子名称:MB2760, CALCIUM ION
著者Johansson, P., Arand, M., Unge, T., Bergfors, T., Jones, T.A., Mowbray, S.L.
登録日2005-03-24
公開日2005-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of an Atypical Epoxide Hydrolase from Mycobacterium Tuberculosis Gives Insights Into its Function.
J.Mol.Biol., 351, 2005
2C2I
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STRUCTURE AND FUNCTION OF RV0130, A CONSERVED HYPOTHETICAL PROTEIN FROM M.TUBERCULOSIS
分子名称:RV0130
著者Johansson, P., Castell, A., Jones, T.A., Backbro, K.
登録日2005-09-29
公開日2006-09-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Function of Rv0130, a Conserved Hypothetical Protein from Mycobacterium Tuberculosis.
Protein Sci., 15, 2006
2WAS
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STRUCTURE OF THE FUNGAL TYPE I FAS PPT DOMAIN
分子名称:3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE
著者Johansson, P., Mulincacci, B., Koestler, C., Grininger, M.
登録日2009-02-15
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Multimeric Options for the Auto-Activation of the Saccharomyces Cerevisiae Fas Type I Megasynthase.
Structure, 17, 2009
2WAT
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STRUCTURE OF THE FUNGAL TYPE I FAS PPT DOMAIN IN COMPLEX WITH COA
分子名称:3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, CHLORIDE ION, COENZYME A, ...
著者Johansson, P., Mulincacci, B., Koestler, C., Grininger, M.
登録日2009-02-15
公開日2009-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Multimeric Options for the Auto-Activation of the Saccharomyces Cerevisiae Fas Type I Megasynthase.
Structure, 17, 2009
2YOP
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LONG WAVELENGTH S-SAD STRUCTURE OF FAM3B PANDER
分子名称:PROTEIN FAM3B, GLYCEROL
著者Johansson, P., Bernstrom, J., Gorman, T., Oster, L., Backstrom, S., Schweikart, F., Xu, B., Xue, Y., Holmberg Schiavone, L.
登録日2012-10-26
公開日2013-01-30
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fam3B Pander and Fam3C Ilei Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-Like Fold.
Structure, 21, 2013
2YOQ
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STRUCTURE OF FAM3B PANDER E30 CONSTRUCT
分子名称:PROTEIN FAM3B, GLYCEROL
著者Johansson, P., Bernstrom, J., Gorman, T., Oster, L., Backstrom, S., Schweikart, F., Xu, B., Xue, Y., Holmberg Schiavone, L.
登録日2012-10-26
公開日2013-01-30
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Fam3B Pander and Fam3C Ilei Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-Like Fold.
Structure, 21, 2013
3HMJ
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SACCHAROMYCES CEREVISIAE FAS TYPE I
分子名称:Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, (2S, ...
著者Johansson, P., Mulinacci, B., Koestler, C., Vollrath, R., Oesterhelt, D., Grininger, M.
登録日2009-05-29
公開日2009-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
Structure, 17, 2009
5JNQ
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MRAY TUNICAMYCIN COMPLEX
分子名称:Phospho-N-acetylmuramoyl-pentapeptide-transferase, Tunicamycin, PALMITIC ACID, ...
著者Johansson, P.
登録日2016-04-30
公開日2017-01-11
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献MraY-antibiotic complex reveals details of tunicamycin mode of action.
Nat. Chem. Biol., 13, 2017
5LC2
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XRAY STRUCTURE OF HUMAN FAM3C ILEI MONOMER
分子名称:Protein FAM3C
著者Johansson, P., Jansson, A.
登録日2016-06-19
公開日2017-08-02
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer.
J. Biol. Chem., 292, 2017
5LC3
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XRAY STRUCTURE OF MOUSE FAM3C ILEI MONOMER
分子名称:Protein FAM3C
著者Johansson, P., Jansson, A.
登録日2016-06-19
公開日2017-08-02
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer.
J. Biol. Chem., 292, 2017
5LC4
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XRAY STRUCTURE OF MOUSE FAM3C ILEI DIMER
分子名称:Protein FAM3C
著者Johansson, P., Jansson, A.
登録日2016-06-19
公開日2017-08-02
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer.
J. Biol. Chem., 292, 2017
4B70
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AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB- LOWERING IN BRAIN
分子名称:BETA-SECRETASE 1, (2S)-2-[3-(3-chlorophenyl)phenyl]-2-methyl-5,6-dihydro-1,3-oxazin-4-amine
著者Gravenfors, Y., Blid, J., Ginman, T., Karlstrom, S., Kihlstrom, J., Kolmodin, K., Lindstrom, J., Berg, S., Kieseritzky, F., Slivo, C., Swahn, B., Viklund, J., Olsson, L., Johansson, P., Eketjall, S., Falting, J., Jeppsson, F., Stromberg, K., Janson, J., Rahm, F.
登録日2012-08-16
公開日2013-06-26
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity.
J.Med.Chem., 56, 2013
4B72
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AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB- LOWERING IN BRAIN
分子名称:BETA-SECRETASE 1, (6R)-6-(4-methoxyphenyl)-2-methyl-6-(3-pyrimidin-5-ylphenyl)pyrrolo[3,4-d][1,3]thiazol-4-amine
著者Gravenfors, Y., Blid, J., Ginman, T., Karlstrom, S., Kihlstrom, J., Kolmodin, K., Lindstrom, J., Berg, S., Kieseritzky, F., Slivo, C., Swahn, B., Viklund, J., Olsson, L., Johansson, P., Eketjall, S., Falting, J., Jeppsson, F., Stromberg, K., Janson, J., Rahm, F.
登録日2012-08-16
公開日2013-06-26
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity.
J.Med.Chem., 56, 2013
4B77
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AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB- LOWERING IN BRAIN
分子名称:BETA-SECRETASE 1, DIMETHYL SULFOXIDE, (5R)-5-(4-methoxyphenyl)-5-(3-pyrimidin-5-ylphenyl)-3,4-dihydropyrrol-2-amine
著者Gravenfors, Y., Blid, J., Ginman, T., Karlstrom, S., Kihlstrom, J., Kolmodin, K., Lindstrom, J., Berg, S., Kieseritzky, F., Slivo, C., Swahn, B., Viklund, J., Olsson, L., Johansson, P., Eketjall, S., Falting, J., Jeppsson, F., Stromberg, K., Janson, J., Rahm, F.
登録日2012-08-16
公開日2013-06-26
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity.
J.Med.Chem., 56, 2013
4B78
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AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB- LOWERING IN BRAIN
分子名称:BETA-SECRETASE 1, (3R,5R)-3-methoxy-5-(4-methoxyphenyl)-5-(3-pyridin-3-ylphenyl)-3,4-dihydropyrrol-2-amine
著者Gravenfors, Y., Blid, J., Ginman, T., Karlstrom, S., Kihlstrom, J., Kolmodin, K., Lindstrom, J., Berg, S., Kieseritzky, F., Slivo, C., Swahn, B., Viklund, J., Olsson, L., Johansson, P., Eketjall, S., Falting, J., Jeppsson, F., Stromberg, K., Janson, J., Rahm, F.
登録日2012-08-16
公開日2013-06-26
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity.
J.Med.Chem., 56, 2013
4AJM
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DEVELOPMENT OF A PLATE-BASED OPTICAL BIOSENSOR METHODOLOGY TO IDENTIFY PDE10 FRAGMENT INHIBITORS
分子名称:CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ZINC ION, ...
著者Geschwindner, S., Johansson, P., Spadola, L., Akerud, T., Back, E., Hillertz, P., Horsefeld, R., Scott, C., Spear, N., Tian, G., Tigerstrom, A., Aharony, D., Albert, J.S.
登録日2012-02-16
公開日2013-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development of a Plate-Based Optical Biosensor Methodology to Identify Pde10 Fragment Inhibitors
To be Published
5NDD
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CRYSTAL STRUCTURE OF A THERMOSTABILISED HUMAN PROTEASE-ACTIVATED RECEPTOR-2 (PAR2) IN COMPLEX WITH AZ8838 AT 2.8 ANGSTROM RESOLUTION
分子名称:Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2, (~{S})-(4-fluoranyl-2-propyl-phenyl)-(1~{H}-imidazol-2-yl)methanol, SODIUM ION, ...
著者Cheng, R.K.Y., Fiez-Vandal, C., Schlenker, O., Edman, K., Aggeler, B., Brown, D.G., Brown, G., Cooke, R.M., Dumelin, C.E., Dore, A.S., Geschwindner, S., Grebner, C., Hermansson, N.-O., Jazayeri, A., Johansson, P., Leong, L., Prihandoko, R., Rappas, M., Soutter, H., Snijder, A., Sundstrom, L., Tehan, B., Thornton, P., Troast, D., Wiggin, G., Zhukov, A., Marshall, F.H., Dekker, N.
登録日2017-03-08
公開日2017-05-03
最終更新日2017-05-17
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Structural insight into allosteric modulation of protease-activated receptor 2.
Nature, 545, 2017
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