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6CN8
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BU of 6cn8 by Molmil
High-resolution structure of ClpC1-NTD binding to Rufomycin-I
Descriptor: ATP-dependent Clp protease ATP-binding subunit ClpC1, CHLORIDE ION, PHOSPHATE ION, ...
Authors:Abad-Zapatero, C, Wolf, N.W.
Deposit date:2018-03-07
Release date:2019-06-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads.
Acs Infect Dis., 5, 2019
6IH0
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BU of 6ih0 by Molmil
Aquifex aeolicus LpxC complex with ACHN-975
Descriptor: N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta -1,3-diynyl]benzamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, ...
Authors:Li, D.Y, Fan, S, Jin, Y.Y, Zhang, C, Lv, G.X, Wu, G.T, Yang, Z.Y.
Deposit date:2018-09-27
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria
Molecules, 26, 2021

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