Author results

5DDT
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CRYSTAL STRUCTURE OF ISPD FROM BACILLUS SUBTILIS AT 1.80 ANGSTROMS RESOLUTION, CRYSTAL FORM I
分子名称:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
著者Jin, Y., Liu, Z.C., Wang, G.G.
登録日2015-08-25
公開日2016-08-31
最終更新日2016-11-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
5DDV
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CRYSTAL STRUCTURE OF ISPD FROM BACILLUS SUBTILIS AT 2.30 ANGSTROMS RESOLUTION, CRYSTAL FORM II
分子名称:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
著者Jin, Y., Liu, Z.C., Wang, G.G.
登録日2015-08-25
公開日2016-08-31
最終更新日2016-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
5HS2
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CRYSTAL STRUCTURE OF ISPD COMPLEXED WITH CTP AND MG2+ FROM BACILLUS SUBTILIS AT 1.90 ANGSTROMS RESOLUTION
分子名称:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Jin, Y., Liu, Z.C., Wang, G.G.
登録日2016-01-24
公開日2016-11-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Sci Rep, 6, 2016
1IHI
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CRYSTAL STRUCTURE OF HUMAN TYPE III 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACID BINDING PROTEIN (AKR1C2) COMPLEXED WITH NADP+ AND URSODEOXYCHOLATE
分子名称:3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISO-URSODEOXYCHOLIC ACID
著者Jin, Y., Stayrook, S.E., Albert, R.H., Palackal, N.T., Penning, T.M., Lewis, M.
登録日2001-04-19
公開日2001-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human type III 3alpha-hydroxysteroid dehydrogenase/bile acid binding protein complexed with NADP(+) and ursodeoxycholate.
Biochemistry, 40, 2001
5G0M
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BETA-GLUCURONIDASE WITH AN ACTIVITY-BASED PROBE (N-ACYL CYCLOPHELLITOL AZIRIDINE) BOUND
分子名称:BETA-GLUCURONIDASE, PHOSPHATE ION, (1S,2R,3R,4S,6S)-6-[(8-azidooctanoyl)amino]-2,3,4-trihydroxycyclohexane-1-carboxylate
著者Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
登録日2016-03-21
公開日2017-04-12
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of a Bacteria Beta-Glucuronidase in Gh79 Family
To be Published
5JTS
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STRUCTURE OF A BETA-1,4-MANNANASE, SSGH134.
分子名称:beta-1,4-mannanase, GLYCEROL, 1,2-ETHANEDIOL, ...
著者Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
登録日2016-05-09
公開日2016-11-16
最終更新日2019-10-30
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5JU9
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STRUCTURE OF A BETA-1,4-MANNANASE, SSGH134, IN COMPLEX WITH MAN3.
分子名称:beta-1,4-mannanase, BETA-D-MANNOSE, ALPHA-D-MANNOSE, ...
著者Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
登録日2016-05-10
公開日2016-11-16
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5JUG
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STRUCTURE OF AN INACTIVE (E45Q) VARIANT OF A BETA-1,4-MANNANASE, SSGH134, IN COMPLEX WITH MAN5
分子名称:beta-1,4-mannanase, BETA-D-MANNOSE, ALPHA-D-MANNOSE, ...
著者Jin, Y., Petricevic, M., Goddard-Borger, E.D., Williams, S.J., Davies, G.J.
登録日2016-05-10
公開日2016-11-16
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
ACS Cent Sci, 2, 2016
5AED
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31
分子名称:ALPHA-GLUCOSIDASE YIHQ, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION
著者Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
登録日2015-08-28
公開日2016-02-10
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5AEE
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31
分子名称:ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION, 4-NITROPHENYL-ALPHA-D-SULFOQUINOVOSIDE, ...
著者Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
登録日2015-08-28
公開日2016-02-10
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5AEG
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A BACTERIAL PROTEIN STRUCTURE IN GLYCOSIDE HYDROLASE FAMILY 31.
分子名称:ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION, CHLORIDE ION, ...
著者Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.
登録日2015-08-30
公開日2016-02-10
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids.
Nat.Chem.Biol., 12, 2016
5FOO
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6-PHOSPHO-BETA-GLUCOSIDASE
分子名称:6-PHOSPHO-BETA-D GLYCOSIDASE, 6-PHOSPHOCYCLOPHELLITOL, 1,2-ETHANEDIOL, ...
著者Jin, Y., Kwan, D.H., Withers, S.G., Davies, G.J.
登録日2015-11-24
公開日2016-02-17
最終更新日2016-03-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Chemoenzymatic Synthesis of 6-Phospho-Cyclophellitol as a Novel Probe of 6-Phospho-Beta-Glucosidases.
FEBS Lett., 590, 2016
5G0Q
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BETA-GLUCURONIDASE WITH AN ACTIVITY-BASED PROBE (N-ALKYL CYCLOPHELLITOL AZIRIDINE) BOUND
分子名称:BETA-GLUCURONIDASE, (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, GLYCEROL
著者Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
登録日2016-03-22
公開日2017-04-12
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5L77
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A GLYCOSIDE HYDROLASE MUTANT WITH AN UNREACTED ACTIVITY BASED PROBE BOUND
分子名称:beta-glucuronidase, PHOSPHATE ION, (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, ...
著者Jin, Y., Wu, L., Jiang, J.B., Overkleeft, H.S., Davies, G.J.
登録日2016-06-02
公開日2017-05-31
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
5M77
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A GH76 FAMILY ENZYME STRUCTURE
分子名称:Alpha-1,6-mannanase, 1,2-ETHANEDIOL, (2~{R},3~{S},4~{S},5~{S},6~{R})-2-[[(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methylsulfanyl]-6-(hydroxymethyl)oxane-3,4,5-triol, ...
著者Jin, Y., Williams, S., Davies, G.
登録日2016-10-26
公開日2017-08-09
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-alpha-mannanase inhibitor.
Chem. Commun. (Camb.), 53, 2017
5N0F
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THE CATALYTIC DOMAIN, BCGH76, OF BACILLUS CIRCULANS AMAN6 IN COMPLEX WITH 1,6-MANSIFG
分子名称:Alpha-1,6-mannanase, (2~{R},3~{S},4~{S},5~{S},6~{R})-2-[[(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methylsulfanyl]-6-(hydroxymethyl)oxane-3,4,5-triol
著者Jin, Y., Williams, S., Davies, G.
登録日2017-02-02
公開日2017-08-09
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-alpha-mannanase inhibitor.
Chem. Commun. (Camb.), 53, 2017
5OHS
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A GH31 FAMILY SULFOQUINOVOSIDASE MUTANT D455N IN COMPLEX WITH PNPSQ
分子名称:Alpha-glucosidase yihQ, THIOCYANATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
著者Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
登録日2017-07-18
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHT
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A GH31 FAMILY SULFOQUINOVOSIDASE FROM E. COLI IN COMPLEX WITH AZA-SUGAR INHIBITOR IFGSQ
分子名称:Sulfoquinovosidase, CALCIUM ION, [(3~{S},4~{R},5~{R})-4,5-bis(oxidanyl)piperidin-3-yl]methanesulfonic acid
著者Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
登録日2017-07-18
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
5OHY
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A GH31 FAMILY SULFOQUINOVOSIDASE IN COMPLEX WITH AZA-SUGAR INHIBITOR IFGSQ
分子名称:Alpha-glucosidase yihQ, POTASSIUM ION, 1,2-ETHANEDIOL, ...
著者Jin, Y., Williams, S.J., Goddard-Borger, E., Davies, G.J.
登録日2017-07-18
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases.
ACS Cent Sci, 4, 2018
6R3V
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CRYSTAL STRUCTURE OF RHOA-GDP-PI IN COMPLEX WITH RHOGAP
分子名称:Rho GTPase-activating protein 1, Transforming protein RhoA, PHOSPHATE ION, ...
著者Jin, Y.
登録日2019-03-21
公開日2019-05-08
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A GAP-GTPase-GDP-PiIntermediate Crystal Structure Analyzed by DFT Shows GTP Hydrolysis Involves Serial Proton Transfers.
Chemistry, 25, 2019
3H5V
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CRYSTAL STRUCTURE OF THE GLUR2-ATD
分子名称:Glutamate receptor 2, N-ACETYL-D-GLUCOSAMINE
著者Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3H5W
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CRYSTAL STRUCTURE OF THE GLUR2-ATD IN SPACE GROUP P212121 WITHOUT SOLVENT
分子名称:Glutamate receptor 2
著者Jin, R., Singh, S.K., Gu, S., Furukawa, H., Sobolevsky, A., Zhou, J., Jin, Y., Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
1O5T
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CRYSTAL STRUCTURE OF THE AMINOACYLATION CATALYTIC FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
分子名称:Tryptophanyl-tRNA synthetase
著者Yu, Y., Liu, Y., Shen, N., Xu, X., Jia, J., Jin, Y., Arnold, E., Ding, J.
登録日2003-10-05
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment
J.BIOL.CHEM., 279, 2004
6GQ3
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HUMAN ASPARAGINE SYNTHETASE (ASNS) IN COMPLEX WITH 6-DIAZO-5-OXO-L-NORLEUCINE (DON) AT 1.85 A RESOLUTION
分子名称:Asparagine synthetase [glutamine-hydrolyzing], 5-OXO-L-NORLEUCINE, 1,2-ETHANEDIOL, ...
著者Zhu, W., Radadiya, A., Bisson, C., Jin, Y., Nordin, B.E., Imasaki, T., Wenzel, S., Sedelnikova, S.E., Berry, A.H., Nomanbhoy, T.K., Kozarich, J.W., Takagi, Y., Rice, D.W., Richards, N.G.J.
登録日2018-06-07
公開日2019-09-18
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Commun Biol, 2, 2019
5IWX
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BACILLUS SUBTITIS
分子名称:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MAGNESIUM ION
著者Liu, Z.C., Jin, Y., Wang, G.G.
登録日2016-03-23
公開日2017-03-29
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly among IspD/IspE/IspF enzymes in the MEP pathway.
Biosci. Rep., 2018