Author results

4ID7
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ACK1 KINASE IN COMPLEX WITH THE INHIBITOR CIS-3-[8-AMINO-1-(4-PHENOXYPHENYL)IMIDAZO[1,5-A]PYRAZIN-3-YL]CYCLOBUTANOL
Descriptor:Activated CDC42 kinase 1, cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol, SULFATE ION
Authors:Jin, M., Wang, J., Kleinberg, A., Kadalbajoo, M., Siu, K., Cooke, A., Bittner, M., Yao, Y., Thelemann, A., Ji, Q., Bhagwat, S., Crew, A.P., Pachter, J., Epstein, D., Mulvihill, M.J.
Deposit date:2012-12-11
Release date:2013-01-30
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5H1J
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5
Descriptor:Gem-associated protein 5
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1K
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH 13-NT U4 SNRNA FRAGMENT
Descriptor:Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3')
Authors:Wang, Y., Jin, W., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1L
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH 7-NT U4 SNRNA FRAGMENT
Descriptor:Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3'), GLYCEROL
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1M
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CRYSTAL STRUCTURE OF WD40 REPEAT DOMAINS OF GEMIN5 IN COMPLEX WITH M7G
Descriptor:Gem-associated protein 5, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Jin, W., Wang, Y., Liu, C.P., Yang, N., Jin, M., Cong, Y., Wang, M., Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
4KNB
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C-MET IN COMPLEX WITH OSI LIGAND
Descriptor:Hepatocyte growth factor receptor, 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE
Authors:Wang, J., Steinig, A.G., Li, A.H., Chen, X., Dong, H., Ferraro, C., Jin, M., Kadalbajoo, M., Kleinberg, A., Stolz, K.M., Tavares-Greco, P.A., Wang, T., Albertella, M.R., Peng, Y., Crew, L., Kahler, J.
Deposit date:2013-05-09
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Bioorg.Med.Chem.Lett., 23, 2013
4IP3
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COMPLEX STRUCTURE OF OSPI AND UBC13
Descriptor:ORF169b, Ubiquitin-conjugating enzyme E2 N
Authors:Fu, P., Jin, M., Zhang, X., Xu, L., Xia, Z., Zhu, Y.
Deposit date:2013-01-09
Release date:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure Analysis of Ubc13 Inactivation
To be Published
5GW4
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STRUCTURE OF YEAST NPP-TRIC
Descriptor:T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Zang, Y., Jin, M., Wang, H., Cong, Y.
Deposit date:2016-09-08
Release date:2016-10-26
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
5GW5
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STRUCTURE OF TRIC-AMP-PNP
Descriptor:T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Zang, Y., Jin, M., Wang, H., Cong, Y.
Deposit date:2016-09-08
Release date:2016-10-26
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
5JDB
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BINDING SPECIFICITY OF P[8] VP8* PROTEINS OF ROTAVIRUS VACCINE STRAINS WITH HISTO-BLOOD GROUP ANTIGENS
Descriptor:Outer capsid protein VP4
Authors:Sun, X., Guo, N., Li, D., Zhou, Y., Jin, M., Xie, G., Pang, L., Zhang, Q., Cao, Y., Duan, Z.
Deposit date:2016-04-16
Release date:2016-07-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens.
Virology, 495, 2016
5WCO
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MATRIX PROTEIN (M1) OF INFECTIOUS SALMON ANAEMIA VIRUS
Descriptor:NS2
Authors:Zhang, W., Zheng, W., Toh, Y., Betancourt, M.A., Tu, J., Fan, Y., Vakharia, V., Liu, J., McNew, J.A., Jin, M., Tao, Y.J.
Deposit date:2017-07-01
Release date:2017-08-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5YSX
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STRUCTURE OF P DOMAIN OF GII.2 NOROVIRUSES
Descriptor:VP1
Authors:Duan, Z., Ao, Y.
Deposit date:2017-11-16
Release date:2018-08-08
Method:X-RAY DIFFRACTION (1.202 Å)
Cite:Genetic Analysis of Reemerging GII.P16-GII.2 Noroviruses in 2016-2017 in China.
J. Infect. Dis., 218, 2018
3BN3
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CRYSTAL STRUCTURE OF ICAM-5 IN COMPLEX WITH AL I DOMAIN
Descriptor:Integrin alpha-L, Intercellular adhesion molecule 5, MAGNESIUM ION, ...
Authors:Zhang, H., Springer, T.A., Wang, J.-h.
Deposit date:2007-12-13
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5
Mol.Cell, 31, 2008
5GJ6
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FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF P[19] ROTAVIRUS VP8* INTERACTION WITH HISTO-BLOOD GROUP ANTIGENS
Descriptor:Outer capsid protein VP4, SULFATE ION
Authors:Sun, X., Duan, Z.
Deposit date:2016-06-28
Release date:2016-09-07
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Functional and Structural Characterization of P[19] Rotavirus VP8* Interaction with Histo-blood Group Antigens.
J. Virol., 90, 2016
5YMS
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STRUCTURAL BASIS OF GLYCAN SPECIFICITY AND IDENTIFICATION OF A NOVEL GLYCAN BINDING CAVITY IN HUMAN P[19] ROTAVIRUS
Descriptor:Outer capsid protein VP4, N-ACETYL-D-GLUCOSAMINE, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
Authors:Sun, X., Dandi, L., Duan, Z.
Deposit date:2017-10-22
Release date:2018-05-02
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s.
J. Virol., 92, 2018
5YMT
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FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF P[19] ROTAVIRUS VP8* INTERACTION WITH HISTO-BLOOD GROUP ANTIGENS
Descriptor:Outer capsid protein VP4, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sun, X., Duan, Z.
Deposit date:2017-10-22
Release date:2018-05-02
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s.
J. Virol., 92, 2018
5YMU
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FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF P[19] ROTAVIRUS VP8* INTERACTION WITH HISTO-BLOOD GROUP ANTIGENS
Descriptor:Outer capsid protein VP4, GLYCEROL
Authors:Sun, X., Duan, Z.
Deposit date:2017-10-22
Release date:2018-05-23
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycan Binding Specificity and Mechanism of Human and Porcine P[6]/P[19] Rotavirus VP8*s.
J. Virol., 92, 2018