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1F1B
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CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE R-STATE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ASPARTATE
分子名称:ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
著者Jin, L., Stec, B., Kantrowitz, E.R.
登録日2000-05-18
公開日2000-11-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
1PZU
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AN ASYMMETRIC NFAT1-RHR HOMODIMER ON A PSEUDO-PALINDROMIC, KAPPA-B SITE
分子名称:5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', Nuclear factor of activated T-cells, ...
著者Jin, L., Sliz, P., Chen, L., Macian, F., Rao, A., Hogan, P.G., Harrison, S.C.
登録日2003-07-14
公開日2003-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
Nat.Struct.Biol., 10, 2003
1AZX
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ANTITHROMBIN/PENTASACCHARIDE COMPLEX
分子名称:ANTITHROMBIN, N-ACETYL-D-GLUCOSAMINE, HEPARIN PENTASACCHARIDE
著者Jin, L., Abrahams, J.P., Skinner, R., Petitou, M., Pike, R.N., Carrell, R.W.
登録日1997-11-23
公開日1999-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The anticoagulant activation of antithrombin by heparin.
Proc.Natl.Acad.Sci.USA, 94, 1997
1D09
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ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH N-PHOSPHONACETYL-L-ASPARTATE (PALA)
分子名称:ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
著者Jin, L., Stec, B., Lipscomb, W.N., Kantrowitz, E.R.
登録日1999-09-09
公開日2000-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into the mechanisms of catalysis and heterotropic regulation of Escherichia coli aspartate transcarbamoylase based upon a structure of the enzyme complexed with the bisubstrate analogue N-phosphonacetyl-L-aspartate at 2.1 A.
Proteins, 37, 1999
1ET1
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CRYSTAL STRUCTURE OF HUMAN PARATHYROID HORMONE 1-34 AT 0.9 A RESOLUTION
分子名称:PARATHYROID HORMONE, SODIUM ION
著者Jin, L., Briggs, S.L., Chandrasekhar, S., Chirgadze, N.Y., Clawson, D.K., Schevitz, R.W., Smiley, D.L., Tashjian, A.H., Zhang, F.
登録日2000-04-12
公開日2000-09-06
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution.
J.Biol.Chem., 275, 2000
1EZZ
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CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE
分子名称:ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION
著者Jin, L., Stec, B., Kantrowitz, E.R.
登録日2000-05-12
公開日2000-11-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
1MF8
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CRYSTAL STRUCTURE OF HUMAN CALCINEURIN COMPLEXED WITH CYCLOSPORIN A AND HUMAN CYCLOPHILIN
分子名称:CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ALPHA ISOFORM, CALCINEURIN B SUBUNIT ISOFORM 1, ...
著者Jin, L., Harrison, S.C.
登録日2002-08-09
公開日2002-10-16
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin
Proc.Natl.Acad.Sci.USA, 99, 2002
1U59
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CRYSTAL STRUCTURE OF THE ZAP-70 KINASE DOMAIN IN COMPLEX WITH STAUROSPORINE
分子名称:Tyrosine-protein kinase ZAP-70, STAUROSPORINE
著者Jin, L., Pluskey, S., Petrella, E.C., Cantin, S.M., Gorga, J.C., Rynkiewicz, M.J., Pandey, P., Strickler, J.E., Babine, R.E., Weaver, D.T., Seidl, K.J.
登録日2004-07-27
公開日2004-08-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS
J.Biol.Chem., 279, 2004
1XX9
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH ECOTINM84R
分子名称:Coagulation factor XI, Ecotin, N-ACETYL-D-GLUCOSAMINE
著者Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2004-11-04
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
1XXD
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH MUTATED ECOTIN
分子名称:Coagulation factor XI, Ecotin
著者Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2004-11-04
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
1XXF
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CRYSTAL STRUCTURE OF THE FXIA CATALYTIC DOMAIN IN COMPLEX WITH ECOTIN MUTANT (ECOTINP)
分子名称:Coagulation factor XI, Ecotin, SODIUM ION
著者Jin, L., Pandey, P., Babine, R.E., Gorga, J.C., Seidl, K.J., Gelfand, E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2004-11-04
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of the FXIa Catalytic Domain in Complex with Ecotin Mutants Reveal Substrate-like Interactions
J.Biol.Chem., 280, 2005
1ZHM
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE COAGULATION FACTOR XIA IN COMPLEX WITH BENZAMIDINE (S434A-T475A-K437 MUTANT)
分子名称:coagulation factor XI, BENZAMIDINE, GLUTATHIONE
著者Jin, L., Pandey, P., Babine, R.E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2005-04-26
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.
Acta Crystallogr.,Sect.D, 61, 2005
1ZHP
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH BENZAMIDINE (S434A-T475A-K505 MUTANT)
分子名称:coagulation factor XI, BENZAMIDINE, GLUTATHIONE
著者Jin, L., Pandey, P., Babine, R.E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2005-04-26
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.
Acta Crystallogr.,Sect.D, 61, 2005
1ZHR
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH BENZAMIDINE (S434A-T475A-C482S-K437A MUTANT)
分子名称:coagulation factor XI, BENZAMIDINE
著者Jin, L., Pandey, P., Babine, R.E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2005-04-26
公開日2005-09-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Mutation of surface residues to promote crystallization of activated factor XI as a complex with benzamidine: an essential step for the iterative structure-based design of factor XI inhibitors.
Acta Crystallogr.,Sect.D, 61, 2005
3CMO
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HIV NEUTRALIZING MONOCLONAL ANTIBODY YZ18
分子名称:Fab light chain, Fab heavy chain
著者Jin, L., Prasad, V., Paul, S.
登録日2008-03-24
公開日2008-08-05
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HIV neutralizing monoclonal antibody YZ18
TO BE PUBLISHED
3GLR
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CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ACETYL-LYSINE ACECS2 PEPTIDE
分子名称:NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ...
著者Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B.
登録日2009-03-12
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
3GLS
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CRYSTAL STRUCTURE OF HUMAN SIRT3
分子名称:NAD-dependent deacetylase sirtuin-3, mitochondrial, ZINC ION, ...
著者Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B.
登録日2009-03-12
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
3GLT
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CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ADPR BOUND TO THE ACECS2 PEPTIDE CONTAINING A THIOACETYL LYSINE
分子名称:NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ...
著者Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B.
登録日2009-03-12
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
3GLU
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CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ACECS2 PEPTIDE
分子名称:NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ...
著者Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B.
登録日2009-03-12
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
1ZJD
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF COAGULATION FACTOR XI IN COMPLEX WITH KUNITZ PROTEASE INHIBITOR DOMAIN OF PROTEASE NEXIN II
分子名称:Catalytic Domain of Coagulation Factor XI, Kunitz Protease Inhibitory Domain of Protease Nexin II
著者Jin, L., Navaneetham, D., Pandey, P., Strickler, J.E., Babine, R.E., Walsh, P.N., Abdel-Meguid, S.S.
登録日2005-04-28
公開日2005-08-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2
J.Biol.Chem., 280, 2005
2FDA
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COAGULATION FACTOR XIA IN COMPLEX WITH ALPHA-KETOTHIAZOLE ARGININE DERIVED LIGAND
分子名称:Coagulation factor XI, BICARBONATE ION, SULFATE ION, ...
著者Jin, L., Pandey, P., Babine, R.E., Weaver, D.T., Abdel-Meguid, S.S., Strickler, J.E.
登録日2005-12-13
公開日2006-04-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine
Bioorg.Med.Chem.Lett., 16, 2006
1AKM
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ORNITHINE TRANSCARBAMYLASE FROM ESCHERICHIA COLI
分子名称:ORNITHINE TRANSCARBAMYLASE
著者Head, J.F., Seaton, B., Jin, L.
登録日1997-05-23
公開日1998-05-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure at 2.8 A resolution of anabolic ornithine transcarbamylase from Escherichia coli.
Nat.Struct.Biol., 4, 1997
3CLE
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HIV NEUTRALIZING MONOCLONAL ANTIBODY YZ23
分子名称:Fab light chain, Fab heavy chain
著者Jin, L., Paul, S., Symersky, J.
登録日2008-03-18
公開日2008-03-25
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献HIV neutralizing monoclonal antibody YZ23
To be Published
3QOW
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DOT1L STRUCTURE IN COMPLEX WITH SAM
分子名称:Histone-lysine N-methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION
著者Jin, L.
登録日2011-02-11
公開日2011-05-25
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Chemogenetic analysis of human protein methyltransferases.
Chem.Biol.Drug Des., 78, 2011
3QOX
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DOT1L STRUCTURE IN COMPLEX WITH SAH
分子名称:Histone-lysine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
著者Jin, L.
登録日2011-02-11
公開日2011-05-25
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Chemogenetic analysis of human protein methyltransferases.
Chem.Biol.Drug Des., 78, 2011