Author results

1AM0
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AMP RNA APTAMER COMPLEX, NMR, 8 STRUCTURES
分子名称:RNA APTAMER, ADENOSINE MONOPHOSPHATE
著者Jiang, F., Kumar, R.A., Jones, R.A., Patel, D.J.
登録日1997-06-19
公開日1997-07-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Basis of RNA Folding and Recognition in an AMP-RNA Aptamer Complex
Nature, 382, 1996
1EXY
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SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET
分子名称:RNA APTAMER, 33-MER, HTLV-1 REX PEPTIDE
著者Jiang, F., Gorin, A., Hu, W., Majumdar, A., Baskerville, S., Xu, W., Ellington, A., Patel, D.J.
登録日2000-05-05
公開日2000-05-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
2E2C
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E2-C, AN UBIQUITIN CONJUGATING ENZYME REQUIRED FOR THE DESTRUCTION OF MITOTIC CYCLINS
分子名称:UBIQUITIN CONJUGATING ENZYME
著者Jiang, F., Basavappa, R.
登録日1999-01-19
公開日1999-01-27
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the cyclin-specific ubiquitin-conjugating enzyme from clam, E2-C, at 2.0 A resolution.
Biochemistry, 38, 1999
3GAS
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CRYSTAL STRUCTURE OF HELICOBACTER PYLORI HEME OXYGENASE HUGZ IN COMPLEX WITH HEME
分子名称:heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE, AZIDE ION, ...
著者Jiang, F., Hu, Y.L., Guo, Y., Guo, G., Zou, Q.M., Wang, D.C.
登録日2009-02-18
公開日2010-02-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme
To be Published
4ZT0
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CRYSTAL STRUCTURE OF CATALYTICALLY-ACTIVE STREPTOCOCCUS PYOGENES CAS9 IN COMPLEX WITH SINGLE-GUIDE RNA AT 2.9 ANGSTROM RESOLUTION
分子名称:CRISPR-associated endonuclease Cas9, single-guide RNA
著者Jiang, F., Doudna, J.A.
登録日2015-05-14
公開日2015-07-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
4ZT9
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NUCLEASE-INACTIVE STREPTOCOCCUS PYOGENES CAS9 (D10A/H840A, DCAS9) IN COMPLEX WITH SINGLE-GUIDE RNA AT 3.1 ANGSTROM RESOLUTION
分子名称:CRISPR-associated endonuclease Cas9, single-guide RNA
著者Jiang, F., Doudna, J.A.
登録日2015-05-14
公開日2015-07-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
5E3H
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STRUCTURAL BASIS FOR RNA RECOGNITION AND ACTIVATION OF RIG-I
分子名称:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3'), ZINC ION, ...
著者Jiang, F., Miller, M.T., Marcotrigiano, J.
登録日2015-10-02
公開日2015-11-18
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
5F9R
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CRYSTAL STRUCTURE OF CATALYTICALLY-ACTIVE STREPTOCOCCUS PYOGENES CRISPR-CAS9 IN COMPLEX WITH SINGLE-GUIDED RNA AND DOUBLE-STRANDED DNA PRIMED FOR TARGET DNA CLEAVAGE
分子名称:CRISPR-associated endonuclease Cas9/Csn1, RNA (116-MER), DNA (30-MER), ...
著者Jiang, F., Doudna, J.A.
登録日2015-12-10
公開日2016-01-27
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Science, 351, 2016
6J0B
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH-TUBE COMPLEX IN EXTENDED STATE
分子名称:Pvc2, Pvc1
著者Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
登録日2018-12-23
公開日2019-04-10
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0C
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH COMPLEX IN CONTRACTED STATE
分子名称:Pvc2
著者Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
登録日2018-12-23
公開日2019-04-10
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0F
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC SHEATH/TUBE TERMINATOR IN EXTENDED STATE
分子名称:Pvc16, Pvc1
著者Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
登録日2018-12-24
公開日2019-04-10
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0M
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, PVC BASEPLATE IN EXTENDED STATE (RECONSTRUCTED WITH C3 SYMMETRY)
分子名称:Pvc8
著者Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
登録日2018-12-24
公開日2019-04-10
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0N
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CRYO-EM STRUCTURE OF AN EXTRACELLULAR CONTRACTILE INJECTION SYSTEM, BASEPLATE IN EXTENDED STATE, REFINED IN C6 SYMMETRY
分子名称:Pvc9, Pvc11, Pvc12, ...
著者Jiang, F., Li, N., Wang, X., Cheng, J., Huang, Y., Yang, Y., Yang, J., Cai, B., Wang, Y., Jin, Q., Gao, N.
登録日2018-12-25
公開日2019-04-10
最終更新日2019-04-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6MCB
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CRYOEM STRUCTURE OF ACRIIA2 IN COMPLEX WITH CRISPR-CAS9
分子名称:Single guide RNA (116-MER), CRISPR-associated endonuclease Cas9, Anti-CRISPR protein AcrIIA2
著者Jiang, F., Liu, J.J., Doudna, J.A.
登録日2018-08-31
公開日2019-01-16
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
Mol. Cell, 73, 2019
6MCC
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CRYOEM STRUCTURE OF ACRIIA2 HOMOLOG IN COMPLEX WITH CRISPR-CAS9
分子名称:Single guide RNA (116-MER), CRISPR-associated endonuclease Cas9, Anti-CRISPR AcrIIA2 Homolog
著者Jiang, F., Liu, J.J., Doudna, J.A.
登録日2018-08-31
公開日2019-01-16
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
Mol. Cell, 73, 2019
4OGC
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CRYSTAL STRUCTURE OF THE TYPE II-C CAS9 ENZYME FROM ACTINOMYCES NAESLUNDII
分子名称:HNH endonuclease domain protein, ZINC ION, MANGANESE (II) ION, ...
著者Jiang, F., Ma, E., Lin, S., Doudna, J.A.
登録日2014-01-15
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4OGE
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CRYSTAL STRUCTURE OF THE TYPE II-C CAS9 ENZYME FROM ACTINOMYCES NAESLUNDII
分子名称:HNH endonuclease domain protein, ZINC ION, MAGNESIUM ION, ...
著者Jiang, F., Ma, E., Lin, S., Doudna, J.A.
登録日2014-01-15
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
5VZL
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CRYO-EM STRUCTURE OF THE CAS9-SGRNA-ACRIIA4 ANTI-CRISPR COMPLEX
分子名称:single guide RNA (116-MER), CRISPR-associated endonuclease Cas9, phage anti-CRISPR AcrIIA4
著者Jiang, F., Liu, J.J., Nogales, E., Doudna, J.A.
登録日2017-05-29
公開日2017-07-26
最終更新日2019-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Disabling Cas9 by an anti-CRISPR DNA mimic.
Sci Adv, 3, 2017
2NS2
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CRYSTAL STRUCTURE OF SPINDLIN1
分子名称:Spindlin-1, PHOSPHATE ION
著者Zhao, Q., Qin, L., Jiang, F., Wu, B., Yue, W., Xu, F., Rong, Z., Yuan, H., Xie, X., Gao, Y., Bai, C., Bartlam, M.
登録日2006-11-02
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation
J.Biol.Chem., 282, 2007
5I95
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ISOCITRATE DEHYDROGENASE R140Q MUTANT HOMODIMER BOUND TO NADPH AND ALPHA-KETOGLUTARIC ACID
分子名称:Isocitrate dehydrogenase [NADP], mitochondrial, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Zhang, B., Jin, L., Wu, W., Jiang, F., DeLaBarre, B., Travins, J.A., Padyana, A.K.
登録日2016-02-19
公開日2017-03-01
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov, 7, 2017
5I96
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ISOCITRATE DEHYDROGENASE (IDH2) R140Q MUTANT HOMODIMER IN COMPLEX WITH AG-221 (ENASIDENIB) INHIBITOR.
分子名称:Isocitrate dehydrogenase [NADP], mitochondrial, CALCIUM ION, ...
著者Wei, W., Zhang, B., Jin, L., Jiang, F., DeLaBarre, B., Travins, J.A., Padyana, A.K.
登録日2016-02-19
公開日2017-03-08
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov, 7, 2017
3UNW
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH GLUTAMATE
分子名称:Glutaminase kidney isoform, mitochondrial, GLUTAMIC ACID
著者DeLaBarre, B., Gross, S., Cheng, F., Gao, Y., Jha, A., Jiang, F., Song, J.J., Wie, W., Hurov, J.
登録日2011-11-16
公開日2011-12-07
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50, 2011
3UO9
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH GLUTAMATE AND BPTES
分子名称:Glutaminase kidney isoform, mitochondrial, GLYCEROL, ...
著者DeLaBarre, B., Gross, S., Cheng, F., Gao, Y., Jha, A., Jiang, F., Song, J.J., Wei, W., Hurov, J.B.
登録日2011-11-16
公開日2011-12-07
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50, 2011
1C76
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STAPHYLOKINASE (SAK) MONOMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
1C77
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STAPHYLOKINASE (SAK) DIMER
分子名称:STAPHYLOKINASE
著者Rao, Z., Jiang, F., Liu, Y., Zhang, X., Chen, Y., Bartlam, M., Song, H., Ding, Y.
登録日2000-02-01
公開日2000-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
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