Author results

1J4H
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CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000107 SMALL MOLECULE
Descriptor:FKBP12, 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER
Authors:Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z.
Deposit date:2001-09-30
Release date:2003-06-03
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
1J4I
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CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000308 SMALL MOLECULE
Descriptor:FKBP12, 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID
Authors:Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z.
Deposit date:2001-09-30
Release date:2003-06-03
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
1SEK
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THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION
Descriptor:SERPIN K
Authors:Li, J., Wang, Z., Canagarajah, B., Jiang, H., Kanost, M., Goldsmith, E.J.
Deposit date:1998-03-06
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of active serpin 1K from Manduca sexta.
Structure Fold.Des., 7, 1999
2BX3
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P43212)
Descriptor:MAIN PROTEINASE
Authors:Verschueren, K.H.G., Mesters, J.R., Hilgenfeld, R.
Deposit date:2005-07-22
Release date:2005-09-26
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ph-Dependent Conformational Flexibility of the Sars-Cov Main Proteinase (M(Pro)) Dimer: Molecular Dynamics Simulations and Multiple X-Ray Structure Analyses.
J.Mol.Biol., 354, 2005
2BX4
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (P21212)
Descriptor:3C-LIKE PROTEINASE
Authors:Verschueren, K.H.G., Mesters, J.R., Bigalke, J., Hilgenfeld, R.
Deposit date:2005-07-22
Release date:2005-09-26
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Ph-Dependent Conformational Flexibility of the Sars-Cov Main Proteinase (M(Pro)) Dimer: Molecular Dynamics Simulations and Multiple X-Ray Structure Analyses.
J.Mol.Biol., 354, 2005
2EW5
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STRUCTURE OF HELICOBACTER PYLORI PEPTIDE DEFORMYLASE IN COMPLEX WITH INHIBITOR
Descriptor:peptide deformylase, COBALT (II) ION, 4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE
Authors:Cai, J.
Deposit date:2005-11-02
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
2EW6
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STRUCTURE OF HELICOBACTER PYLORI PEPTIDE DEFORMYLASE IN COMPLEX WITH INHIBITOR
Descriptor:peptide deformylase, COBALT (II) ION, (2E)-3-(3,4-DIHYDROXYPHENYL)-N-[2-(4-HYDROXYPHENYL)ETHYL]ACRYLAMIDE
Authors:Cai, J.
Deposit date:2005-11-02
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
2EW7
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CRYSTAL STRUCTURE OF HELICOBACTER PYLORI PEPTIDE DEFORMYLASE
Descriptor:peptide deformylase, COBALT (II) ION
Authors:Cai, J.
Deposit date:2005-11-02
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
Protein Sci., 15, 2006
2GHU
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CRYSTAL STRUCTURE OF FALCIPAIN-2 FROM PLASMODIUM FALCIPARUM
Descriptor:falcipain 2
Authors:Hogg, T., Nagarajan, K., Schmidt, C.L., Hilgenfeld, R.
Deposit date:2006-03-27
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Characterization of Falcipain-2, a Hemoglobinase from the Malarial Parasite Plasmodium falciparum.
J.Biol.Chem., 281, 2006
2GLL
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE(FABZ) FROM HELICOBACTER PYLORI
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-04-05
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
J.Biol.Chem., 283, 2008
2GLM
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE(FABZ) FROM HELICOBACTER PYLORI COMPLEXED WITH COMPOUND 2
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-04-05
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
J.Biol.Chem., 283, 2008
2GLP
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE(FABZ) FROM HELICOBACTER PYLORI COMPLEXED WITH COMPOUND 1
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-04-05
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
J.Biol.Chem., 283, 2008
2GLV
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE(FABZ) MUTANT(Y100A) FROM HELICOBACTER PYLORI
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-04-05
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
J.Biol.Chem., 283, 2008
2H12
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STRUCTURE OF ACETOBACTER ACETI CITRATE SYNTHASE COMPLEXED WITH OXALOACETATE AND CARBOXYMETHYLDETHIA COENZYME A (CMX)
Descriptor:Citrate synthase, OXALOACETATE ION, SULFATE ION, ...
Authors:Starks, C.M., Kappock, T.J.
Deposit date:2006-05-15
Release date:2006-09-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of a NADH-insensitive hexameric citrate synthase that resists acid inactivation.
Biochemistry, 45, 2006
2H1Y
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CRYSTAL STRUCTURE OF MALONYL-COA:ACYL CARRIER PROTEIN TRANSACYLASE (MCAT) FROM HELICOBACTER PYLORI
Descriptor:Malonyl coenzyme A-acyl carrier protein transacylase
Authors:Zhang, L., Liu, W., Shen, X., Jiang, H.
Deposit date:2006-05-17
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein
Protein Sci., 16, 2007
2JQC
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A L-AMINO ACID MUTANT OF A D-AMINO ACID CONTAINING CONOPEPTIDE
Descriptor:L-mr12
Authors:Huang, F., Du, W., Han, Y., Wang, C., Chi, C.
Deposit date:2007-05-31
Release date:2008-04-15
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Purification and structural characterization of a d-amino acid-containing conopeptide, conomarphin, from Conus marmoreus
Febs J., 275, 2008
2JR8
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SOLUTION STRUCTURE OF MANDUCA SEXTA MORICIN
Descriptor:Antimicrobial peptide moricin
Authors:Gong, Y., Dai, H., Rayaprolu, S., Huang, R., Prakash, O., Jiang, H.
Deposit date:2007-06-21
Release date:2008-03-25
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Solution structure, antibacterial activity, and expression profile of Manduca sexta moricin.
J.Pept.Sci., 14, 2008
2NAE
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MEMBRANE-BOUND MOUSE CD28 CYTOPLASMIC TAIL
Descriptor:T-cell-specific surface glycoprotein CD28
Authors:Li, H., Xu, C., Pan, W.
Deposit date:2015-12-23
Release date:2016-12-21
Last modified:2017-11-01
Method:SOLUTION NMR
Cite:Dynamic regulation of CD28 conformation and signaling by charged lipids and ions
Nat. Struct. Mol. Biol., 2017
2OJU
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X-RAY STRUCTURE OF COMPLEX OF HUMAN CYCLOPHILIN J WITH CYCLOSPORIN A
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3, CYCLOSPORIN A
Authors:Xia, Z., Huang, L.
Deposit date:2007-01-14
Release date:2008-01-22
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Targeting Cyclophilin J, a Novel Peptidyl-Prolyl Isomerase, Can Induce Cellular G1/S Arrest and Repress the Growth of Hepatocellular Carcinoma
To be Published
2OK3
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X-RAY STRUCTURE OF HUMAN CYCLOPHILIN J AT 2.0 ANGSTROM
Descriptor:Peptidyl-prolyl cis-trans isomerase-like 3, NICKEL (II) ION
Authors:Xia, Z.
Deposit date:2007-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma
To be Published
2PVP
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CRYSTAL STRUCTURE OF D-ALANINE-D-ALANINE LIGASE FROM HELICOBACTER PYLORI
Descriptor:D-alanine-D-alanine ligase
Authors:Wu, D., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-05-10
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori.
Proteins, 72, 2008
2PWX
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CRYSTAL STRUCTURE OF G11A MUTANT OF SARS-COV 3C-LIKE PROTEASE
Descriptor:3C-like proteinase
Authors:Chen, S., Hu, T., Jiang, H., Shen, X.
Deposit date:2007-05-14
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations.
J.Biol.Chem., 283, 2008
2QGH
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE DECARBOXYLASE FROM HELICOBACTER PYLORI COMPLEXED WITH L-LYSINE
Descriptor:Diaminopimelate decarboxylase, PYRIDOXAL-5'-PHOSPHATE, LYSINE, ...
Authors:Hu, T., Wu, D., Jiang, H., Shen, X.
Deposit date:2007-06-28
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori complexed with L-lysine
TO BE PUBLISHED
2RJG
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
2RJH
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CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D-CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI
Descriptor:Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
Authors:Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X.
Deposit date:2007-10-15
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008