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1AM0
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BU of 1am0 by Molmil
AMP RNA APTAMER COMPLEX, NMR, 8 STRUCTURES
Descriptor: ADENOSINE MONOPHOSPHATE, RNA APTAMER
Authors:Jiang, F, Kumar, R.A, Jones, R.A, Patel, D.J.
Deposit date:1997-06-19
Release date:1997-07-23
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structural Basis of RNA Folding and Recognition in an AMP-RNA Aptamer Complex
Nature, 382, 1996
1EXY
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BU of 1exy by Molmil
SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET
Descriptor: HTLV-1 REX PEPTIDE, RNA APTAMER, 33-MER
Authors:Jiang, F, Gorin, A, Hu, W, Majumdar, A, Baskerville, S, Xu, W, Ellington, A, Patel, D.J.
Deposit date:2000-05-05
Release date:2000-05-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
3GAS
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BU of 3gas by Molmil
Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme
Descriptor: 1,2-ETHANEDIOL, AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Jiang, F, Hu, Y.L, Guo, Y, Guo, G, Zou, Q.M, Wang, D.C.
Deposit date:2009-02-18
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Helicobacter pylori Heme Oxygenase Hugz in Complex with Heme
To be Published
4ZT9
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BU of 4zt9 by Molmil
Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
4ZT0
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BU of 4zt0 by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
5E3H
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BU of 5e3h by Molmil
Structural Basis for RNA Recognition and Activation of RIG-I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
Authors:Jiang, F, Miller, M.T, Marcotrigiano, J.
Deposit date:2015-10-02
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
5F9R
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BU of 5f9r by Molmil
Crystal structure of catalytically-active Streptococcus pyogenes CRISPR-Cas9 in complex with single-guided RNA and double-stranded DNA primed for target DNA cleavage
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (30-MER), DNA (5'-D(P*AP*TP*GP*AP*GP*AP*CP*GP*CP*TP*GP*GP*AP*GP*TP*AP*CP*AP*C)-3'), ...
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-12-10
Release date:2016-01-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Science, 351, 2016
6J0B
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BU of 6j0b by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath-tube complex in extended state
Descriptor: Pvc1, Pvc2
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-23
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0C
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BU of 6j0c by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath complex in contracted state
Descriptor: Pvc2
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-23
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0F
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BU of 6j0f by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath/tube terminator in extended state
Descriptor: Pvc1, Pvc16
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-24
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0N
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BU of 6j0n by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry
Descriptor: Pvc1, Pvc11, Pvc12, ...
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-25
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0M
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BU of 6j0m by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry)
Descriptor: Pvc8
Authors:Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
Deposit date:2018-12-24
Release date:2019-04-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6MCC
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BU of 6mcc by Molmil
CryoEM structure of AcrIIA2 homolog in complex with CRISPR-Cas9
Descriptor: Anti-CRISPR AcrIIA2 Homolog, CRISPR-associated endonuclease Cas9, Single guide RNA (116-MER)
Authors:Jiang, F, Liu, J.J, Doudna, J.A.
Deposit date:2018-08-31
Release date:2019-01-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
Mol. Cell, 73, 2019
6MCB
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BU of 6mcb by Molmil
CryoEM structure of AcrIIA2 in complex with CRISPR-Cas9
Descriptor: Anti-CRISPR protein AcrIIA2, CRISPR-associated endonuclease Cas9, Single guide RNA (116-MER)
Authors:Jiang, F, Liu, J.J, Doudna, J.A.
Deposit date:2018-08-31
Release date:2019-01-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Temperature-Responsive Competitive Inhibition of CRISPR-Cas9.
Mol. Cell, 73, 2019
2E2C
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BU of 2e2c by Molmil
E2-C, AN UBIQUITIN CONJUGATING ENZYME REQUIRED FOR THE DESTRUCTION OF MITOTIC CYCLINS
Descriptor: UBIQUITIN CONJUGATING ENZYME
Authors:Jiang, F, Basavappa, R.
Deposit date:1999-01-19
Release date:1999-01-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the cyclin-specific ubiquitin-conjugating enzyme from clam, E2-C, at 2.0 A resolution.
Biochemistry, 38, 1999
6JJ3
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BU of 6jj3 by Molmil
BRD4 in complex with 138A
Descriptor: 2-methoxy-N-[2-methyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]benzenesulfonamide, Bromodomain-containing protein 4
Authors:Xu, J, Chen, Y, Jiang, F, Zhu, J.
Deposit date:2019-02-25
Release date:2020-01-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.718 Å)
Cite:Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis.
J.Med.Chem., 62, 2019
5VZL
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BU of 5vzl by Molmil
cryo-EM structure of the Cas9-sgRNA-AcrIIA4 anti-CRISPR complex
Descriptor: CRISPR-associated endonuclease Cas9, phage anti-CRISPR AcrIIA4, single guide RNA (116-MER)
Authors:Jiang, F, Liu, J.J, Nogales, E, Doudna, J.A.
Deposit date:2017-05-29
Release date:2017-07-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Disabling Cas9 by an anti-CRISPR DNA mimic.
Sci Adv, 3, 2017
6JJB
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BU of 6jjb by Molmil
BRD4 in complex with ZZM1
Descriptor: 2-methoxy-N-(1-methyl-2-oxidanylidene-benzo[cd]indol-6-yl)benzenesulfonamide, Bromodomain-containing protein 4
Authors:Xu, J, Chen, Y, Jiang, F, Zhu, J.
Deposit date:2019-02-25
Release date:2020-01-22
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.508 Å)
Cite:Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis.
J.Med.Chem., 62, 2019
4OGC
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BU of 4ogc by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4OGE
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BU of 4oge by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
1C76
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BU of 1c76 by Molmil
STAPHYLOKINASE (SAK) MONOMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
1C78
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BU of 1c78 by Molmil
STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C77
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BU of 1c77 by Molmil
STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C79
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BU of 1c79 by Molmil
STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C8J
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BU of 1c8j by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F)
Descriptor: CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z.
Deposit date:2000-05-31
Release date:2001-05-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F)
To be Published

 

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