5WZZ
 
 | | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation | | Descriptor: | Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION | | Authors: | Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. | | Deposit date: | 2017-01-19 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.103 Å) | | Cite: | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
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7YFN
 | | Core module of the NuA4 complex in S. cerevisiae | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ... | | Authors: | Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q. | | Deposit date: | 2022-07-08 | | Release date: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7YFP
 | | The NuA4 histone acetyltransferase complex from S. cerevisiae | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ARP4 isoform 1, Actin, ... | | Authors: | Ji, L.T, Zhao, L.X, Xu, K, Gao, H.H, Zhou, Y, Kornberg, R.D, Zhang, H.Q. | | Deposit date: | 2022-07-08 | | Release date: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure of the NuA4 histone acetyltransferase complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1D9S
 | | TUMOR SUPPRESSOR P15(INK4B) STRUCTURE BY COMPARATIVE MODELING AND NMR DATA | | Descriptor: | CYCLIN-DEPENDENT KINASE 4 INHIBITOR B | | Authors: | Yuan, C, Ji, L, Selby, T.L, Byeon, I.J.L, Tsai, M.D. | | Deposit date: | 1999-10-29 | | Release date: | 2000-07-28 | | Last modified: | 2022-02-16 | | Method: | SOLUTION NMR | | Cite: | Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C).
J.Mol.Biol., 294, 1999
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3HTX
 | | Crystal structure of small RNA methyltransferase HEN1 | | Descriptor: | 5'-R(*GP*AP*UP*UP*UP*CP*UP*CP*UP*CP*UP*GP*CP*AP*AP*GP*CP*GP*AP*AP*AP*G)-3', 5'-R(P*UP*UP*CP*GP*CP*UP*UP*GP*CP*AP*GP*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*C)-3', HEN1, ... | | Authors: | Huang, Y, Ji, L.-J, Huang, Q.-C, Vassylyev, D.G, Chen, X.-M, Ma, J.-B. | | Deposit date: | 2009-06-12 | | Release date: | 2009-09-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Nature, 461, 2009
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4RUT
 | | crystal structure of murine cyclooxygenase-2 with 13-methyl-arachidonic Acid | | Descriptor: | (5Z,8Z,11Z,13S,14Z)-13-methylicosa-5,8,11,14-tetraenoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Xu, S, Kudalkar, S.N, Banerjee, S, Makriyannis, A, Nikas, S.P, Marnett, L.J. | | Deposit date: | 2014-11-21 | | Release date: | 2015-02-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | 13-methylarachidonic Acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.
J.Biol.Chem., 290, 2015
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8IFG
 | | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | | Descriptor: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | | Authors: | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | | Deposit date: | 2023-02-17 | | Release date: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Class I histone deacetylase complex: Structure and functional correlates.
Proc Natl Acad Sci U S A, 120, 2023
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8GHV
 | | Cannabinoid Receptor 1-G Protein Complex | | Descriptor: | (5Z,8Z,11Z,13S,14Z)-N-[(2R)-1-hydroxypropan-2-yl]-13-methylicosa-5,8,11,14-tetraenamide, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Krishna Kumar, K, Robertson, M.J, Skiniotis, G, Kobilka, B.K. | | Deposit date: | 2023-03-12 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for activation of CB1 by an endocannabinoid analog.
Nat Commun, 14, 2023
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7A8R
 | | Structure of RecQL from Bos taurus | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, MAGNESIUM ION, ... | | Authors: | Rety, S, Chen, W.F, Xi, X.G. | | Deposit date: | 2020-08-30 | | Release date: | 2021-10-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Endogenous Bos taurus RECQL is predominantly monomeric and more active than oligomers.
Cell Rep, 36, 2021
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8OUW
 | | Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans) | | Descriptor: | Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ... | | Authors: | Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M. | | Deposit date: | 2023-04-25 | | Release date: | 2023-08-16 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans.
Science, 381, 2023
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