Author results

1IBG
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STRUCTURE AND SPECIFICITY OF THE ANTI-DIGOXIN ANTIBODY 40-50
Descriptor:IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN), IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN), COPPER (II) ION, ...
Authors:Jeffrey, P.D., Sheriff, S.
Deposit date:1994-10-25
Release date:1995-05-08
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and Specificity of the Anti-Digoxin Antibody 40-50
J.Mol.Biol., 248, 1995
1BP5
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HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM
Descriptor:PROTEIN (SERUM TRANSFERRIN)
Authors:Jeffrey, P.D., Bewley, M.C., Macgillivray, R.T.A., Mason, A.B., Woodworth, R.C., Baker, E.N.
Deposit date:1998-08-12
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
Biochemistry, 37, 1998
1BTJ
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HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM, CRYSTAL FORM 2
Descriptor:PROTEIN (SERUM TRANSFERRIN)
Authors:Jeffrey, P.D., Bewley, M.C., Macgillivray, R.T.A., Mason, A.B., Woodworth, R.C., Baker, E.N.
Deposit date:1998-09-01
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
Biochemistry, 37, 1998
1C26
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CRYSTAL STRUCTURE OF P53 TETRAMERIZATION DOMAIN
Descriptor:P53 TUMOR SUPPRESSOR
Authors:Jeffrey, P.D., Gorina, S., Pavletich, N.P.
Deposit date:1999-07-22
Release date:1999-07-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.
Science, 267, 1995
1FIN
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CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 2, CYCLIN A, ADENOSINE-5'-TRIPHOSPHATE
Authors:Jeffrey, P.D., Russo, A.A., Pavletich, N.P.
Deposit date:1996-07-14
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376, 1995
1G3N
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STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX
Descriptor:CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE 6 INHIBITOR, V-CYCLIN
Authors:Jeffrey, P.D., Tong, L., Pavletich, N.P.
Deposit date:2000-10-24
Release date:2001-01-10
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors.
Genes Dev., 14, 2000
1IGI
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26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
Descriptor:IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN), IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN)
Authors:Jeffrey, P.D., Sheriff, S.
Deposit date:1993-02-19
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
Proc.Natl.Acad.Sci.USA, 90, 1993
1IGJ
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26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
Descriptor:IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN), IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN), DIGOXIN
Authors:Jeffrey, P.D., Sheriff, S.
Deposit date:1993-02-19
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
Proc.Natl.Acad.Sci.USA, 90, 1993
1DKJ
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BOBWHITE QUAIL LYSOZYME
Descriptor:LYSOZYME
Authors:Jeffrey, P.D., Sheriff, S.
Deposit date:1996-01-10
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
1DKK
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BOBWHITE QUAIL LYSOZYME WITH NITRATE
Descriptor:LYSOZYME, NITRATE ION
Authors:Jeffrey, P.D., Sheriff, S.
Deposit date:1996-01-10
Release date:1996-07-11
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
2P1L
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STRUCTURE OF THE BCL-XL:BECLIN 1 COMPLEX
Descriptor:Apoptosis regulator Bcl-X, Beclin 1
Authors:Jeffrey, P.D., Shi, Y., Oberstein, A.L.
Deposit date:2007-03-05
Release date:2007-03-13
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
J.Biol.Chem., 282, 2007
2PKG
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STRUCTURE OF A COMPLEX BETWEEN THE A SUBUNIT OF PROTEIN PHOSPHATASE 2A AND THE SMALL T ANTIGEN OF SV40
Descriptor:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION
Authors:Jeffrey, P.D., Shi, Y.
Deposit date:2007-04-17
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.
Nat.Struct.Mol.Biol., 14, 2007
3B4R
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SITE-2 PROTEASE FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:Putative zinc metalloprotease MJ0392, ZINC ION
Authors:Jeffrey, P.D., Feng, L., Yan, H., Wu, Z., Yan, N., Wang, Z., Shi, Y.
Deposit date:2007-10-24
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a site-2 protease family intramembrane metalloprotease.
Science, 318, 2007
3H11
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ZYMOGEN CASPASE-8:C-FLIPL PROTEASE DOMAIN COMPLEX
Descriptor:CASP8 and FADD-like apoptosis regulator, Caspase-8, IETD aldehyde inhibitor
Authors:Jeffrey, P.D., Yu, J.W., Shi, Y.
Deposit date:2009-04-10
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of procaspase-8 activation by c-FLIPL.
Proc.Natl.Acad.Sci.USA, 106, 2009
3H13
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C-FLIPL PROTEASE-LIKE DOMAIN
Descriptor:CASP8 and FADD-like apoptosis regulator
Authors:Jeffrey, P.D., Yu, J.W., Shi, Y.
Deposit date:2009-04-10
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of procaspase-8 activation by c-FLIPL.
Proc.Natl.Acad.Sci.USA, 106, 2009
3H43
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N-TERMINAL DOMAIN OF THE PROTEASOME-ACTIVATING NUCLEOTIDASE OF METHANOCALDOCOCCUS JANNASCHII
Descriptor:Proteasome-activating nucleotidase
Authors:Jeffrey, P.D., Zhang, F., Hu, M., Tian, G., Zhang, P., Finley, D., Shi, Y.
Deposit date:2009-04-17
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
3H4P
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PROTEASOME 20S CORE PARTICLE FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:Proteasome subunit alpha, Proteasome subunit beta
Authors:Jeffrey, P.D., Zhang, F., Hu, M., Tian, G., Zhang, P., Finley, D., Shi, Y.
Deposit date:2009-04-20
Release date:2009-06-09
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
3K7V
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PROTEIN PHOSPHATASE 2A CORE COMPLEX BOUND TO DINOPHYSISTOXIN-1
Descriptor:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, SULFATE ION, ...
Authors:Jeffrey, P.D., Huhn, J., Shi, Y.
Deposit date:2009-10-13
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A structural basis for the reduced toxicity of dinophysistoxin-2.
Chem.Res.Toxicol., 22, 2009
3K7W
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PROTEIN PHOSPHATASE 2A CORE COMPLEX BOUND TO DINOPHYSISTOXIN-2
Descriptor:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, SULFATE ION, ...
Authors:Jeffrey, P.D., Huhn, J., Shi, Y.
Deposit date:2009-10-13
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:A structural basis for the reduced toxicity of dinophysistoxin-2.
Chem.Res.Toxicol., 22, 2009
3UO8
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CRYSTAL STRUCTURE OF THE MALT1 PARACASPASE (P1 FORM)
Descriptor:Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Z-Val-Arg-Pro-DL-Arg-fluoromethylketone
Authors:Jeffrey, P.D., Yu, J.W., Shi, Y.
Deposit date:2011-11-16
Release date:2011-12-21
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UOA
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CRYSTAL STRUCTURE OF THE MALT1 PARACASPASE (P21 FORM)
Descriptor:Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Z-Val-Arg-Pro-DL-Arg-fluoromethylketone, MAGNESIUM ION
Authors:Jeffrey, P.D., Yu, J.W., Shi, Y.
Deposit date:2011-11-16
Release date:2011-12-21
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region.
Proc.Natl.Acad.Sci.USA, 108, 2011
5IT3
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SWIRM DOMAIN OF HUMAN LSD1
Descriptor:Lysine-specific histone demethylase 1A, MAGNESIUM ION
Authors:Jeffrey, P.D., Yuan, P.
Deposit date:2016-03-16
Release date:2016-05-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells
To Be Published
5BUZ
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE SNARE VAM3 AND THE HOPS VPS33-VPS16 SUBCOMPLEX FROM CHAETOMIUM THERMOPHILUM
Descriptor:SM (Sec1/Munc18-like) protein, Putative vacuolar protein sorting-associated protein, SNAP receptor-like protein
Authors:Baker, R.W., Jeffrey, P.D., Hughson, F.M.
Deposit date:2015-06-04
Release date:2015-08-05
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5BV0
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE SNARE NYV1 AND THE HOPS VPS33-VPS16 SUBCOMPLEX FROM CHAETOMIUM THERMOPHILUM
Descriptor:SM (Sec1/Munc18-like) protein, Vps16, SNARE domain
Authors:Baker, R.W., Jeffrey, P.D., Hughson, F.M.
Deposit date:2015-06-04
Release date:2015-08-05
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5BV1
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CRYSTAL STRUCTURE OF A VPS33-VPS16 COMPLEX FROM CHAETOMIUM THERMOPHILUM
Descriptor:VPS33, Putative vacuolar protein sorting-associated protein, D-MALATE
Authors:Baker, R.W., Jeffrey, P.D., Hughson, F.M.
Deposit date:2015-06-04
Release date:2015-08-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015