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5VYP
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CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NSD7 BOUND TO PIP2
Descriptor:Defensin NsD7, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, SULFATE ION, ...
Authors:Jarva, M., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-05-25
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type.
FEBS Lett., 591, 2017
6B55
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CRYSTAL STRUCTURE OF THE PLANT DEFENSIN NAD1 COMPLEXED WITH PHOSPHATIDIC ACID
Descriptor:Flower-specific defensin, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, PHOSPHATE ION, ...
Authors:Jarva, M., Phan, K., Humble, C., Lay, F.T., Hulett, M., Kvansakul, M.
Deposit date:2017-09-28
Release date:2018-05-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Nat Commun, 9, 2018
6CS9
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CRYSTAL STRUCTURE OF HUMAN BETA-DEFENSIN 2 IN COMPLEX WITH PIP2
Descriptor:Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Jarva, M., Phan, K., Lay, F.T., Humble, C., Hulett, M., Kvansakul, M.
Deposit date:2018-03-20
Release date:2018-07-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization.
Sci Adv, 4, 2018
4JC6
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MERCURY ACTIVATION OF THE PLANT AQUAPORIN SOPIP2;1 - STRUCTURAL AND FUNCTIONAL CHARACTERIZATION
Descriptor:Aquaporin, B-OCTYLGLUCOSIDE, CADMIUM ION, ...
Authors:Frick, A., Jarva, M., Nyblom, M., Ekvall, M., Uzdavinys, P., Tornroth-Horsefield, S.
Deposit date:2013-02-21
Release date:2013-09-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Mercury increases water permeability of a plant aquaporin through a non-cysteine-related mechanism.
Biochem.J., 454, 2013
6FMD
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TARGETING MYELOID DIFFERENTIATION USING POTENT HUMAN DIHYDROOROTATE DEHYDROGENASE (HDHODH) INHIBITORS BASED ON 2-HYDROXYPYRAZOLO[1,5-A]PYRIDINE SCAFFOLD
Descriptor:Dihydroorotate dehydrogenase (quinone), mitochondrial, 2-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]pyrazolo[1,5-a]pyridine-3-carboxamide, ...
Authors:Goyal, P., Jarva, M., Andersson, M., Lolli, M.L., Friemann, R.
Deposit date:2018-01-30
Release date:2018-07-11
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
J. Med. Chem., 61, 2018
4IA4
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STRUCTURE OF THE SPINACH AQUAPORIN SOPIP2;1 AT PH 6
Descriptor:Aquaporin, MERCURY (II) ION
Authors:Frick, A., Jarva, M., Tornroth-Horsefield, S.
Deposit date:2012-12-06
Release date:2013-05-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for pH gating of plant aquaporins
Febs Lett., 587, 2013
6H1N
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CRYSTAL STRUCTURE OF A ZEBRA-FISH PRO-SURVIVAL PROTEIN NRZ-APO
Descriptor:BCL2-like 10 (Apoptosis facilitator), SULFATE ION, ACETATE ION
Authors:Suraweera, C.D., Hinds, M.G., Kvansakul, M.
Deposit date:2018-07-12
Release date:2018-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018