4X6Z
 
 | | Yeast 20S proteasome in complex with PR-VI modulator | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Rostankowski, R, Witkowska, J, Borek, D, Otwinowski, Z, Jankowska, E. | | Deposit date: | 2014-12-09 | | Release date: | 2015-12-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures revealed the common place of binding of low-molecular
mass activators with the 20S proteasome
To Be Published
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1G96
 | | HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING | | Descriptor: | CHLORIDE ION, CYSTATIN C, GLYCEROL | | Authors: | Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M. | | Deposit date: | 2000-11-22 | | Release date: | 2001-04-06 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping.
Nat.Struct.Biol., 8, 2001
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1KHQ
 | | ORTHORHOMBIC FORM OF PAPAIN/ZLFG-DAM COVALENT COMPLEX | | Descriptor: | Papain, peptidic inhibitor | | Authors: | Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Jaskolski, M. | | Deposit date: | 2001-11-30 | | Release date: | 2003-09-09 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor
J.Pept.Res., 64, 2004
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1KHP
 | | Monoclinic form of papain/ZLFG-DAM covalent complex | | Descriptor: | Papain, peptidic inhibitor | | Authors: | Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Jaskolski, M. | | Deposit date: | 2001-11-30 | | Release date: | 2003-09-09 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor
J.Pept.Res., 64, 2004
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8BZL
 | | Human 20S Proteasome in complex with peptide activator peptide BLM42 | | Descriptor: | ARG-SER-TYR-TYR-SER, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Henneberg, F, Chari, A, Jankowska, E, Witkowska, J. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration.
To Be Published
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5NIF
 | | Yeast 20S proteasome in complex with Blm-pep activator | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Witkowska, J, Grudnik, P, Golik, P, Dubin, G, Jankowska, E. | | Deposit date: | 2017-03-23 | | Release date: | 2017-08-02 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome - insights into the enzyme activation mechanism.
Sci Rep, 7, 2017
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3NX0
 | | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C | | Descriptor: | Cystatin-C, SULFATE ION | | Authors: | Orlikowska, M, Jankowska, E, Kolodziejczyk, R, Jaskolski, M, Szymanska, A. | | Deposit date: | 2010-07-12 | | Release date: | 2010-12-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C.
J.Struct.Biol., 173, 2011
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3S67
 | | Crystal structure of V57P mutant of human cystatin C | | Descriptor: | ACETATE ION, CHLORIDE ION, Cystatin-C, ... | | Authors: | Orlikowska, M, Szymanska, A, Borek, D, Otwinowski, Z, Skowron, P, Jankowska, E. | | Deposit date: | 2011-05-25 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein.
Acta Crystallogr.,Sect.D, 69, 2013
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3SVA
 | | Crystal structure of V57D mutant of human cystatin C | | Descriptor: | ACETATE ION, Cystatin-C, DI(HYDROXYETHYL)ETHER | | Authors: | Orlikowska, M, Szymanska, A, Borek, D, Otwinowski, Z, Skowron, P, Jankowska, E. | | Deposit date: | 2011-07-12 | | Release date: | 2012-08-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein.
Acta Crystallogr.,Sect.D, 69, 2013
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3PS8
 | | Crystal structure of L68V mutant of human cystatin C | | Descriptor: | ACETATE ION, Cystatin-C, DI(HYDROXYETHYL)ETHER | | Authors: | Orlikowska, M, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | | Deposit date: | 2010-12-01 | | Release date: | 2011-12-21 | | Last modified: | 2013-04-03 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of L68V mutant of human cystatin C
To be Published
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1R4C
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1TIJ
 | | 3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets | | Descriptor: | Cystatin C | | Authors: | Janowski, R, Kozak, M, Abrahamson, M, Grubb, A, Jaskolski, M. | | Deposit date: | 2004-06-02 | | Release date: | 2005-07-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | 3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets.
Proteins, 61, 2005
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