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7UD4
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BU of 7ud4 by Molmil
Cryo-EM structure of AAV-PHP.eB
Descriptor: Capsid protein VP1
Authors:Jang, S, Shen, H.K, Ding, X, Miles, T.F, Gradinaru, V.
Deposit date:2022-03-18
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Structural basis of receptor usage by the engineered capsid AAV-PHP.eB.
Mol Ther Methods Clin Dev, 26, 2022
6JM9
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BU of 6jm9 by Molmil
cryo-EM structure of DOT1L bound to unmodified nucleosome
Descriptor: DNA strand I, DNA strand J, Histone H2A, ...
Authors:Jang, S, Song, J.J.
Deposit date:2019-03-07
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
6JMA
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BU of 6jma by Molmil
cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome
Descriptor: DNA I&J, Histone H2A, Histone H2B 1.1, ...
Authors:Jang, S, Song, J.J.
Deposit date:2019-03-07
Release date:2019-05-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
3GIO
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BU of 3gio by Molmil
Crystal structure of the TNF-alpha inducing protein (Tip alpha) from Helicobacter pylori
Descriptor: Putative uncharacterized protein
Authors:Jang, J.Y, Yoon, H.J, Yoon, J.Y, Kim, H.S, Lee, S.J, Kim, K.H, Kim, D.J, Han, B.G, Lee, B.I, Jang, S, Suh, S.W.
Deposit date:2009-03-05
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the TNF-alpha-Inducing Protein (Tipalpha) from Helicobacter pylori: Insights into Its DNA-Binding Activity.
J.Mol.Biol., 2009
6GX9
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BU of 6gx9 by Molmil
Crystal structure of the TNPO3 - CPSF6 RSLD complex
Descriptor: BENZAMIDINE, BICINE, Cleavage and polyadenylation specificity factor subunit 6, ...
Authors:Cherepanov, P, Cook, N.
Deposit date:2018-06-26
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.
Nucleic Acids Res., 47, 2019
8EOI
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BU of 8eoi by Molmil
Structure of a human EMC:human Cav1.2 channel complex in GDN detergent
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L.
Deposit date:2022-10-03
Release date:2023-05-24
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
Nature, 619, 2023
8EOG
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BU of 8eog by Molmil
Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine
Descriptor: (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L.
Deposit date:2022-10-03
Release date:2023-05-24
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
Nature, 619, 2023
6SKM
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BU of 6skm by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,12)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-16
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SLQ
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BU of 6slq by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-12,11)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SLU
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BU of 6slu by Molmil
Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,11)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SMU
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BU of 6smu by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,12)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-22
Release date:2020-09-09
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SKN
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BU of 6skn by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8)
Descriptor: Gag protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-16
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6SKK
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BU of 6skk by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8)
Descriptor: capsid protein
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2019-08-15
Release date:2020-08-26
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6W4T
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BU of 6w4t by Molmil
APE1 Y269A phosphorothioate substrate complex with abasic DNA
Descriptor: DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*(48Z)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase
Authors:Freudenthal, B.D, Hoitsma, N.M.
Deposit date:2020-03-11
Release date:2020-06-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.
Nucleic Acids Res., 48, 2020
6W4I
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BU of 6w4i by Molmil
APE1 Y269A product complex with abasic DNA
Descriptor: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Freudenthal, B.D, Hoitsma, N.M.
Deposit date:2020-03-10
Release date:2020-06-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.
Nucleic Acids Res., 48, 2020
6Y9X
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BU of 6y9x by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,7)
Descriptor: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-03-10
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9Z
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BU of 6y9z by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,9)
Descriptor: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-03-10
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9V
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BU of 6y9v by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-8,13)
Descriptor: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-03-10
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9Y
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BU of 6y9y by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-7,13)
Descriptor: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-03-10
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6Y9W
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BU of 6y9w by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,8)
Descriptor: Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-03-10
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6ZDJ
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BU of 6zdj by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,10)
Descriptor: Gag protein, Peptidyl-prolyl cis-trans isomerase A
Authors:Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
Deposit date:2020-06-14
Release date:2020-08-19
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6YJ5
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BU of 6yj5 by Molmil
Focused refinement cryo-EM structure of the yeast mitochondrial complex I sub-stoichiometric sulfur transferase subunit
Descriptor: Rhodanese-like domain-containing protein
Authors:Hirst, J, Grba, D.
Deposit date:2020-04-02
Release date:2020-08-12
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
5UOT
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BU of 5uot by Molmil
CryoEM structure of the helical assembly of full length MxB
Descriptor: Interferon-induced GTP-binding protein Mx2
Authors:Perilla, J.R, Alvarez, F.J.D, Zhang, P, Schulten, K.
Deposit date:2017-02-01
Release date:2018-02-21
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.
Sci Adv, 3, 2017
8HL6
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BU of 8hl6 by Molmil
Crystal structure of human valosin-containing protein methyltransferase
Descriptor: Protein N-lysine methyltransferase METTL21D, S-ADENOSYLMETHIONINE
Authors:Kang, W, Yang, J.K.
Deposit date:2022-11-29
Release date:2023-07-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase.
Iscience, 26, 2023
8HL7
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BU of 8hl7 by Molmil
Crystal structure of p97 N/D1 in complex with a valosin-containing protein methyltransferase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kang, W, Yang, J.K.
Deposit date:2022-11-29
Release date:2023-07-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase.
Iscience, 26, 2023

 

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