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2AO7
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BU of 2ao7 by Molmil
Adam10 Disintegrin and cysteine- rich domain
Descriptor: ADAM 10, SULFATE ION
Authors:Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
3MX0
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BU of 3mx0 by Molmil
Crystal Structure of EphA2 ectodomain in complex with ephrin-A5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ...
Authors:Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3FL7
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BU of 3fl7 by Molmil
Crystal structure of the human ephrin A2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ...
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-12-18
Release date:2009-01-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
5L0Q
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BU of 5l0q by Molmil
Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ...
Authors:Xu, K, Saha, N, Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
6BDZ
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BU of 6bdz by Molmil
ADAM10 Extracellular Domain Bound by the 11G2 Fab
Descriptor: 11G2 Fab Heavy Chain, 11G2 Fab Light Chain, CALCIUM ION, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
6BE6
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BU of 6be6 by Molmil
ADAM10 Extracellular Domain
Descriptor: CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 10, SULFATE ION, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
3MBW
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BU of 3mbw by Molmil
Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1
Descriptor: Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ...
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2010-03-26
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3C8X
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BU of 3c8x by Molmil
Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase
Descriptor: Ephrin type-A receptor 2
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-02-14
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CZU
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BU of 3czu by Molmil
Crystal structure of the human ephrin A2- ephrin A1 complex
Descriptor: Ephrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Wikstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-04-30
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
8GH4
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BU of 8gh4 by Molmil
Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ...
Authors:Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y.
Deposit date:2023-03-09
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.
Biomed Pharmacother, 161, 2023

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