Author results

2AO7
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ADAM10 DISINTEGRIN AND CYSTEINE- RICH DOMAIN
Descriptor:ADAM 10, SULFATE ION
Authors:Janes, P.W., Saha, N., Barton, W.A., Kolev, M.V., Wimmer-Kleikamp, S.H., Nievergall, E., Blobel, C.P., Himanen, J.-P., Lackmann, M., Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
3MX0
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CRYSTAL STRUCTURE OF EPHA2 ECTODOMAIN IN COMPLEX WITH EPHRIN-A5
Descriptor:Ephrin type-A receptor 2, Ephrin-A5, N-ACETYL-D-GLUCOSAMINE
Authors:Himanen, J.P., Yermekbayeva, L., Janes, P.W., Walker, J.R., Xu, K., Atapattu, L., Rajashankar, K.R., Mensinga, A., Lackmann, M., Nikolov, D.B., Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3FL7
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2 ECTODOMAIN
Descriptor:Ephrin receptor, SODIUM ION, CHLORIDE ION, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-12-18
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3C8X
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE
Descriptor:Ephrin type-A receptor 2
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-02-14
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CZU
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2- EPHRIN A1 COMPLEX
Descriptor:Ephrin type-A receptor 2, Ephrin-A1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Wikstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-04-30
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MBW
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CRYSTAL STRUCTURE OF THE HUMAN EPHRIN A2 LBD AND CRD DOMAINS IN COMPLEX WITH EPHRIN A1
Descriptor:Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ...
Authors:Walker, J.R., Yermekbayeva, L., Seitova, A., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-03-26
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
5L0Q
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN ADAM10 D+C DOMAIN AND A CONFORMATION SPECIFIC MAB 8C7.
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, mAb 8C7 light chain, mAb 8C7 heavy chain, ...
Authors:Xu, K., Saha, N., Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
6BDZ
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ADAM10 EXTRACELLULAR DOMAIN BOUND BY THE 11G2 FAB
Descriptor:11G2 Fab Light Chain, 11G2 Fab Heavy Chain, Disintegrin and metalloproteinase domain-containing protein 10, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
6BE6
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ADAM10 EXTRACELLULAR DOMAIN
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017