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4CP3
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BU of 4cp3 by Molmil
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
Descriptor: B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
Authors:Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R.
Deposit date:2014-01-31
Release date:2014-03-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
5ICN
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BU of 5icn by Molmil
HDAC1:MTA1 in complex with inositol-6-phosphate and a novel peptide inhibitor based on histone H4
Descriptor: GLY-ALA-6A0-ARG-HIS, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Millard, C.J, Robertson, N.S, Watson, P.J, Jameson, A.G, Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
6SQO
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BU of 6sqo by Molmil
Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQP
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BU of 6sqp by Molmil
Crystal structure of Cat MDM2-S429E RING domain homodimer
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQS
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BU of 6sqs by Molmil
Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub
Descriptor: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQR
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BU of 6sqr by Molmil
Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
5LXM
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BU of 5lxm by Molmil
Crystal structure of Aurora-A bound to a hydrocarbon-stapled proteomimetic of TPX2
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:McIntyre, P.J, Bayliss, R.
Deposit date:2016-09-22
Release date:2016-11-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix.
ACS Chem. Biol., 11, 2016

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