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1ZZQ
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RAT NNOS D597N MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZZR
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RAT NNOS D597N/M336V DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ZINC ION, ...
Authors:Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZZS
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BOVINE ENOS N368D SINGLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, ACETATE ION, ...
Authors:Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZZT
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BOVINE ENOS N368D/V106M DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, ACETATE ION, ...
Authors:Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZZU
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RAT NNOS D597N/M336V DOUBLE MUTANT WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Flinspach, M.L., Igarashi, J., Jamal, J., Yang, W., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2005-06-14
Release date:2005-12-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1P6H
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6I
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RAT NEURONAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6J
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6K
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RAT NEURONAL NOS D597N MUTANT HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, D-MANNITOL, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6L
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6M
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6N
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
Deposit date:2003-04-29
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1RS6
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RAT NEURONAL NOS HEME DOMAIN WITH D-LYSINE-D-NITROARGININE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, D-MANNITOL, ...
Authors:Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1RS7
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RAT NEURONAL NOS HEME DOMAIN WITH D-PHENYLALANINE-D-NITROARGININE AMIDE BOUND
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-05-18
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1RS8
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH D-LYSINE-D-NITROARGININE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
1RS9
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH D-PHENYLALANINE-D-NITROARGININE AMIDE BOUND
Descriptor:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
Authors:Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
Deposit date:2003-12-09
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
2G6H
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STRUCTURE OF RAT NNOS HEME DOMAIN (BH4 BOUND) IN THE REDUCED FORM
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6I
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STRUCTURE OF RAT NNOS HEME DOMAIN (BH2-BOUND) IN THE REDUCED FORM
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6J
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STRUCTURE OF RAT NNOS (L337N) HEME DOMAIN (4-AMINOBIOPTERIN BOUND) COMPLEXED WITH NO
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6K
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STRUCTURE OF RAT NNOS HEME DOMAIN (BH4 BOUND) COMPLEXED WITH NO
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6L
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STRUCTURE OF RAT NNOS HEME DOMAIN (BH2 BOUND) COMPLEXED WITH NO
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6M
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STRUCTURE OF RAT NNOS HEME DOMAIN (BH4 BOUND) COMPLEXED WITH CO
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6N
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STRCTURE OF RAT NNOS HEME DOMAIN (BH2 BOUND) COMPLEXED WITH CO
Descriptor:Nitric-oxide synthase, brain, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2G6O
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STRUCTURE OF BOVINE ENOS HEME DOMAIN (BH4-FREE) COMPLEXED WITH CO
Descriptor:Nitric-oxide synthase, endothelial, ACETATE ION, ...
Authors:Li, H., Igarashi, J., Jamal, J., Yang, W., Poulos, T.L.
Deposit date:2006-02-24
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
1LZX
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RAT NEURONAL NOS HEME DOMAIN WITH NG-HYDROXY-L-ARGININE BOUND
Descriptor:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
Authors:Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
Deposit date:2002-06-11
Release date:2002-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002