Author results

1KNA
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CHROMO DOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING DIMETHYLLYSINE 9.
Descriptor:HETEROCHROMATIN PROTEIN 1, METHYLATED Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1KNE
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CHROMO DOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 9
Descriptor:HETEROCHROMATIN PROTEIN 1, Trimethylated Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1MT6
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9 WITH ADOHCY
Descriptor:SET9, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-20
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1MUF
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9
Descriptor:SET9
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-23
Release date:2002-11-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1Q3L
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CHROMODOMAIN OF HP1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING MONOMETHYLLYSINE 9.
Descriptor:Heterochromatin protein 1, Histone H3
Authors:Jacobs, S.A., Khorasanizadeh, S.
Deposit date:2003-07-30
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9
To be Published
2B2A
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CRYSTAL STRUCTURE OF THE TEN DOMAIN OF THE TELOMERASE REVERSE TRANSCRIPTASE
Descriptor:Telomerase reverse transcriptase
Authors:Jacobs, S.A., Podell, E.R., Cech, T.R.
Deposit date:2005-09-18
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Nat.Struct.Mol.Biol., 13, 2006
2N35
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FUSION TO A HIGHLY STABLE CONSENSUS ALBUMIN BINDING DOMAIN ALLOWS FOR TUNABLE PHARMACOKINETICS
Descriptor:Albumin binding protein
Authors:Gibbs, A.C., Jacobs, S.A.
Deposit date:2015-05-21
Release date:2015-09-02
Last modified:2015-10-21
Method:SOLUTION NMR
Cite:Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics.
Protein Eng.Des.Sel., 28, 2015
1PDQ
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POLYCOMB CHROMODOMAIN COMPLEXED WITH THE HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 27.
Descriptor:Polycomb protein, Histone H3.3
Authors:Fischle, W., Wang, Y., Jacobs, S.A., Kim, Y., Allis, C.D., Khorasanizadeh, S.
Deposit date:2003-05-20
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
Genes Dev., 17, 2003
3TES
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CRYSTAL STRUCTURE OF TENCON
Descriptor:Tencon
Authors:Luo, J., Jacobs, S., Teplyakov, A., Obmolova, G., O'Neil, K., Gilliland, G.
Deposit date:2011-08-15
Release date:2012-05-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design of novel FN3 domains with high stability by a consensus sequence approach.
Protein Eng.Des.Sel., 25, 2012
3TEU
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CRYSTAL STRUCTURE OF FIBCON
Descriptor:Fibcon, 1,4-DIETHYLENE DIOXIDE
Authors:Luo, J., Jacobs, S., Teplyakov, A., Obmolova, G., O'Neil, K., Gilliland, G.
Deposit date:2011-08-15
Release date:2012-05-16
Method:X-RAY DIFFRACTION (1.002 Å)
Cite:Design of novel FN3 domains with high stability by a consensus sequence approach.
Protein Eng.Des.Sel., 25, 2012
4M6A
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N-TERMINAL BETA-STRAND SWAPPING IN A CONSENSUS DERIVED ALTERNATIVE SCAFFOLD DRIVEN BY STABILIZING HYDROPHOBIC INTERACTIONS
Descriptor:Tencon
Authors:Luo, J., Teplyakov, A., Obmolova, G., Malia, T.J., Chan, W., Jocobs, S.A., O'neil, K.T., Gilliland, G.L.
Deposit date:2013-08-09
Release date:2014-02-26
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:N-terminal beta-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions.
Proteins, 82, 2014
4LPT
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CRYSTAL STRUCTURE OF MONOMERIC TENCON VARIANT P54CR4-31
Descriptor:TENCON variant P54CR4-31
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.544 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
4LPU
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CRYSTAL STRUCTURE OF TENCON VARIANT P40AR2-32R2
Descriptor:TENCON variant P40AR2-32R2
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
4LPV
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CRYSTAL STRUCTURE OF TENCON VARIANT P41BR3-42
Descriptor:TENCON variant P41BR3-42, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Teplyakov, A., Obmolova, G., Luo, J., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
4LPW
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CRYSTAL STRUCTURE OF TENCON VARIANT A6
Descriptor:TENCON variant A6
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
4LPX
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CRYSTAL STRUCTURE OF TENCON VARIANT D4
Descriptor:TENCON variant D4
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
4LPY
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CRYSTAL STRUCTURE OF TENCON VARIANT G10
Descriptor:TENCON variant G10, SODIUM ION
Authors:Teplyakov, A., Obmolova, G., Gilliland, G.L.
Deposit date:2013-07-16
Release date:2014-01-29
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins, 82, 2014
5KNG
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CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9
Descriptor:DARPIN 6G9, PHOSPHATE ION, GLYCEROL
Authors:Teplyakov, A., Malia, T., Obmolova, G., Gilliland, G.
Deposit date:2016-06-28
Release date:2016-12-14
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
5KNH
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CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13
Descriptor:DARPIN 6G9, IL13, ACETATE ION
Authors:Teplyakov, A., Malia, T., Obmolova, G., Gilliland, G.
Deposit date:2016-06-28
Release date:2016-12-14
Last modified:2017-01-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
5L2H
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CRYSTAL STRUCTURE OF W26A MUTANT OF ANTI-EGFR CENTYRIN P54AR4-83V2
Descriptor:Centyrin, GLYCEROL
Authors:Cardoso, R.M.F., Goldberg, S.D., O Neil, K.T., Gilliland, G.L.
Deposit date:2016-08-01
Release date:2016-11-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8013 Å)
Cite:Engineering a targeted delivery platform using Centyrins.
Protein Eng. Des. Sel., 29, 2016
5KF4
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CRYSTAL STRUCTURE OF FN3 DOMAIN (RESIDUES P368-P466) OF HUMAN COLLAGEN XX
Descriptor:Collagen alpha-1(XX) chain
Authors:Xie, Y., Cheng, Z., Zhao, J.
Deposit date:2016-06-12
Release date:2016-07-06
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the second fibronectin type III (FN3) domain from human collagen alpha 1 type XX
Acta Crystallogr F Struct Biol Commun, 73, 2017