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1Z56
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BU of 1z56 by Molmil
Co-Crystal Structure of Lif1p-Lig4p
Descriptor: DNA ligase IV, Ligase interacting factor 1
Authors:Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L.
Deposit date:2005-03-17
Release date:2006-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA REPAIR, 5, 2006
2AZM
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BU of 2azm by Molmil
Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX
Descriptor: GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1
Authors:Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J.
Deposit date:2005-09-12
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.), 123, 2005
3I0M
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BU of 3i0m by Molmil
Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain
Descriptor: DNA repair and telomere maintenance protein nbs1, GLYCEROL
Authors:Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J.
Deposit date:2009-06-25
Release date:2009-10-13
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
3I0N
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BU of 3i0n by Molmil
Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain
Descriptor: DNA repair and telomere maintenance protein nbs1, GLYCEROL
Authors:Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J.
Deposit date:2009-06-25
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
1GXC
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BU of 1gxc by Molmil
FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide
Descriptor: SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE
Authors:Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J.
Deposit date:2002-04-02
Release date:2002-06-13
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Mol.Cell, 9, 2002
1IK9
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BU of 1ik9 by Molmil
CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX
Descriptor: DNA LIGASE IV, DNA REPAIR PROTEIN XRCC4
Authors:Sibanda, B.L, Critchlow, S.E, Begun, J, Pei, X.Y, Jackson, S.P, Blundell, T.L, Pellegrini, L.
Deposit date:2001-05-03
Release date:2001-11-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an Xrcc4-DNA ligase IV complex.
Nat.Struct.Biol., 8, 2001
6HXY
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BU of 6hxy by Molmil
Crystal structure of the head and coiled-coil domains of zebrafish CCDC61
Descriptor: Coiled-coil domain-containing protein 61
Authors:Ochi, T, van Breugel, M.
Deposit date:2018-10-18
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
6HXT
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BU of 6hxt by Molmil
Crystal structure of the head domain of human CCDC61
Descriptor: Coiled-coil domain-containing protein 61
Authors:Ochi, T, Blundell, T.L, van Breugel, M.
Deposit date:2018-10-18
Release date:2020-04-29
Last modified:2020-06-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
6HXV
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BU of 6hxv by Molmil
Crystal structure of the head and coiled-coil domains of zebrafish CCDC61 (F129E/D130A)
Descriptor: Coiled-coil domain-containing protein 61
Authors:Barnabas, D, Ochi, T, van Breugel, M.
Deposit date:2018-10-18
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure, 28, 2020
3WTD
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BU of 3wtd by Molmil
Structure of PAXX
Descriptor: Uncharacterized protein C9orf142
Authors:Ochi, T, Blundell, T.L.
Deposit date:2014-04-09
Release date:2015-01-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Science, 347, 2015
3WTF
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BU of 3wtf by Molmil
Structure of PAXX
Descriptor: Uncharacterized protein C9orf142
Authors:Ochi, T, Blundell, T.L.
Deposit date:2014-04-09
Release date:2015-01-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.451 Å)
Cite:DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Science, 347, 2015
1PCZ
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BU of 1pcz by Molmil
STRUCTURE OF TATA-BINDING PROTEIN
Descriptor: TATA-BINDING PROTEIN
Authors:Dedecker, B.S, Sigler, P.B.
Deposit date:1996-10-04
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a hyperthermophilic archaeal TATA-box binding protein.
J.Mol.Biol., 264, 1996
2N5N
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BU of 2n5n by Molmil
Structure of an N-terminal domain of CHD4
Descriptor: Chromodomain-helicase-DNA-binding protein 4
Authors:Silva, A.P.G, Mackay, J.P.
Deposit date:2015-07-22
Release date:2015-11-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).
J.Biol.Chem., 291, 2016
2QM4
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BU of 2qm4 by Molmil
Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor
Descriptor: Non-homologous end-joining factor 1
Authors:Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L.
Deposit date:2007-07-14
Release date:2007-12-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
4FCX
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BU of 4fcx by Molmil
S.pombe Mre11 apoenzym
Descriptor: DNA repair protein rad32, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-25
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBW
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BU of 4fbw by Molmil
Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site
Descriptor: DNA repair and telomere maintenance protein nbs1, DNA repair protein rad32, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBQ
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BU of 4fbq by Molmil
Crystal structure of a covalently fused Nbs1-Mre11 complex with two manganese ions per active site
Descriptor: DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
4FBK
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BU of 4fbk by Molmil
Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site
Descriptor: DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION, SULFATE ION
Authors:Schiller, C.B, Lammens, K, Hopfner, K.P.
Deposit date:2012-05-23
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.379 Å)
Cite:Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.
Nat.Struct.Mol.Biol., 19, 2012
1D3U
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BU of 1d3u by Molmil
TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor: DNA 23-MER: BRE+TATA-BOX, DNA 24-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ...
Authors:Littlefield, O, Korkhin, Y, Sigler, P.B.
Deposit date:1999-10-01
Release date:1999-11-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for the oriented assembly of a TBP/TFB/promoter complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
1G6G
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BU of 1g6g by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL FHA DOMAIN FROM S. CEREVISIAE RAD53P IN COMPLEX WITH A PHOSPHOTHREONINE PEPTIDE AT 1.6 A RESOLUTION
Descriptor: PROTEIN KINASE RAD53, SER-LEU-GLU-VAL-TPO-GLU-ALA-ASPALA-THR-PHE-ALA-LYS
Authors:Durocher, D, Taylor, I.A.
Deposit date:2000-11-06
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
Mol.Cell, 6, 2000
4D2H
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BU of 4d2h by Molmil
Crystal structure of the tetramerisation domain of human CtIP
Descriptor: RBBP8, SULFATE ION
Authors:Davies, O.R, Sun, M, Pellegrini, L.
Deposit date:2014-05-09
Release date:2015-01-14
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ctip Tetramer Assembly is Required for DNA-End Resection and Repair.
Nat.Struct.Mol.Biol., 22, 2015
1M2K
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BU of 1m2k by Molmil
Sir2 homologue F159A mutant-ADP ribose complex
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION
Authors:Chang, J, Cho, Y.
Deposit date:2002-06-24
Release date:2003-04-08
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural basis for the NAD-dependent deacetylase mechanism of Sir2
J.BIOL.CHEM., 277, 2002
1M2G
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BU of 1m2g by Molmil
Sir2 homologue-ADP ribose complex
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION
Authors:Chang, J, Cho, Y.
Deposit date:2002-06-24
Release date:2003-04-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the NAD-dependent deacetylase mechanism of Sir2
J.BIOL.CHEM., 277, 2002
1M2J
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BU of 1m2j by Molmil
Sir2 homologue H80N mutant-ADP ribose complex
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION
Authors:Chang, J, Cho, Y.
Deposit date:2002-06-24
Release date:2003-04-08
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the NAD-dependent deacetylase mechanism of Sir2
J.BIOL.CHEM., 277, 2002
1M2N
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BU of 1m2n by Molmil
Sir2 homologues (D102G/F159A/R170A) mutant-2'-O-acetyl ADP ribose complex
Descriptor: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION
Authors:Chang, J, Cho, Y.
Deposit date:2002-06-24
Release date:2003-04-08
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the NAD-dependent deacetylase mechanism of Sir2
J.BIOL.CHEM., 277, 2003

 

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