Author results

1BEO
  • Download 1beo
  • View 1beo
Molmil generated image of 1beo
BETA-CRYPTOGEIN
Descriptor:BETA-CRYPTOGEIN
Authors:Boissy, G., De La Fortelle, E., Kahn, R., Huet, J.C., Bricogne, G., Pernollet, J.C., Brunie, S.
Deposit date:1996-08-02
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a fungal elicitor secreted by Phytophthora cryptogea, a member of a novel class of plant necrotic proteins.
Structure, 4, 1996
1HMP
  • Download 1hmp
  • View 1hmp
Molmil generated image of 1hmp
THE CRYSTAL STRUCTURE OF HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE WITH BOUND GMP
Descriptor:HYPOXANTHINE GUANINE PHOSPHORIBOSYL-TRANSFERASE, GUANOSINE-5'-MONOPHOSPHATE
Authors:Eads, J.C., Scapin, G., Xu, Y., Grubmeyer, C., Sacchettini, J.C.
Deposit date:1994-06-03
Release date:1995-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP.
Cell(Cambridge,Mass.), 78, 1994
1AIV
  • Download 1aiv
  • View 1aiv
Molmil generated image of 1aiv
APO OVOTRANSFERRIN
Descriptor:OVOTRANSFERRIN, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Kurokawa, H., Dewan, J.C., Mikami, B., Sacchettini, J.C., Hirose, M.
Deposit date:1997-04-28
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of hen apo-ovotransferrin. Both lobes adopt an open conformation upon loss of iron
J.Biol.Chem., 274, 1999
1KBA
  • Download 1kba
  • View 1kba
Molmil generated image of 1kba
CRYSTAL STRUCTURE OF KAPPA-BUNGAROTOXIN AT 2.3-ANGSTROM RESOLUTION
Descriptor:KAPPA-BUNGAROTOXIN
Authors:Dewan, J.C., Grant, G.A., Sacchettini, J.C.
Deposit date:1994-07-13
Release date:1994-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of kappa-bungarotoxin at 2.3-A resolution.
Biochemistry, 33, 1994
1LD9
  • Download 1ld9
  • View 1ld9
Molmil generated image of 1ld9
THE THREE-DIMENSIONAL STRUCTURE OF AN H-2LD PEPTIDE COMPLEX EXPLAINS THE UNIQUE INTERACTION OF LD WITH BETA2M AND PEPTIDE
Descriptor:MHC CLASS I H-2LD HEAVY CHAIN, BETA-2 MICROGLOBULIN, NANO-PEPTIDE
Authors:Balendiran, G.K., Solheim, J.C., Young, A.C.M., Hansen, T.H., Nathenson, S.G., Sacchettini, J.C.
Deposit date:1997-04-24
Release date:1998-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide.
Proc.Natl.Acad.Sci.USA, 94, 1997
1LIT
  • Download 1lit
  • View 1lit
Molmil generated image of 1lit
HUMAN LITHOSTATHINE
Descriptor:LITHOSTATHINE
Authors:Bertrand, J.A., Pignol, D., Bernard, J.-P., Verdier, J.-M., Dagorn, J.-C., Fontacilla-Camps, J.C.
Deposit date:1996-01-17
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation.
EMBO J., 15, 1996
1NNT
  • Download 1nnt
  • View 1nnt
Molmil generated image of 1nnt
STRUCTURAL EVIDENCE FOR A PH-SENSITIVE DI-LYSINE TRIGGER IN THE HEN OVOTRANSFERRIN N-LOBE: IMPLICATIONS FOR TRANSFERRIN IRON RELEASE
Descriptor:OVOTRANSFERRIN, FE (III) ION, CARBONATE ION
Authors:Dewan, J.C., Mikami, B., Sacchettini, J.C.
Deposit date:1993-09-15
Release date:1994-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural evidence for a pH-sensitive dilysine trigger in the hen ovotransferrin N-lobe: implications for transferrin iron release.
Biochemistry, 32, 1993
1QAP
  • Download 1qap
  • View 1qap
Molmil generated image of 1qap
QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE WITH BOUND QUINOLINIC ACID
Descriptor:QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID
Authors:Eads, J.C., Ozturk, D., Wexler, T.B., Grubmeyer, C., Sacchettini, J.C.
Deposit date:1996-09-20
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase.
Structure, 5, 1997
2IY9
  • Download 2iy9
  • View 2iy9
Molmil generated image of 2iy9
CRYSTAL STRUCTURE OF THE A-SUBUNIT OF THE AB5 TOXIN FROM E. COLI
Descriptor:SUBA
Authors:Paton, A.W., Beddoe, T., Thorpe, C.M., Whisstock, J.C., Wilce, M.C.J., Rossjohn, J., Talbot, U.M., Paton, J.C.
Deposit date:2006-07-13
Release date:2006-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ab5 Subtilase Cytotoxin Inactivates the Endoplasmic Reticulum Chaperone Bip
Nature, 443, 2006
2NQ8
  • Download 2nq8
  • View 2nq8
Molmil generated image of 2nq8
MALARIAL ENOYL ACYL ACP REDUCTASE BOUND WITH INH-NAD ADDUCT
Descriptor:Enoyl-acyl carrier reductase, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE
Authors:Freundlich, J.S., Yu, M., Lucumi, E., Kuo, M., Tsai, H.C., Valderramos, J.C., Karagyozov, L., Jacobs Jr., W.R., Schiehser, G.A., Fidock, D.A., Jacobus, D.P., Sacchettini, J.C.
Deposit date:2006-10-30
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy
J.Biol.Chem., 282, 2007
3DWA
  • Download 3dwa
  • View 3dwa
Molmil generated image of 3dwa
CRYSTAL STRUCTURE OF THE B-SUBUNIT OF THE AB5 TOXIN FROM E. COLI
Descriptor:Subtilase cytotoxin, subunit B, PENTAETHYLENE GLYCOL
Authors:Byres, E., Paton, A.W., Paton, J.C., Lofling, J.C., Smith, D.F., Wilce, M.C.J., Talbot, U.M., Chong, D.C., Yu, H., Huang, S., Chen, X., Varki, N.M., Varki, A., Rossjohn, J., Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.084 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWP
  • Download 3dwp
  • View 3dwp
Molmil generated image of 3dwp
CRYSTAL STRUCTURE OF THE B-SUBUNIT OF THE AB5 TOXIN FROM E. COLI WITH NEU5GC
Descriptor:Subtilase cytotoxin, subunit B, 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ...
Authors:Byres, E., Paton, A.W., Paton, J.C., Lofling, J.C., Smith, D.F., Wilce, M.C.J., Talbot, U.M., Chong, D.C., Yu, H., Huang, S., Chen, X., Varki, N.M., Varki, A., Rossjohn, J., Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3DWQ
  • Download 3dwq
  • View 3dwq
Molmil generated image of 3dwq
CRYSTAL STRUCTURE OF THE A-SUBUNIT OF THE AB5 TOXIN FROM E. COLI WITH NEU5GC-2,3GAL-1,3GLCNAC
Descriptor:Subtilase cytotoxin, subunit B, 3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid, ...
Authors:Byres, E., Paton, A.W., Paton, J.C., Lofling, J.C., Smith, D.F., Wilce, M.C.J., Talbot, U.M., Chong, D.C., Yu, H., Huang, S., Chen, X., Varki, N.M., Varki, A., Rossjohn, J., Beddoe, T.
Deposit date:2008-07-22
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
3H3X
  • Download 3h3x
  • View 3h3x
Molmil generated image of 3h3x
STRUCTURE OF THE V74M LARGE SUBUNIT MUTANT OF NI-FE HYDROGENASE IN AN OXIDIZED STATE
Descriptor:Periplasmic [NiFe] hydrogenase small subunit, Periplasmic [NiFe] hydrogenase large subunit, IRON/SULFUR CLUSTER, ...
Authors:Volbeda, A., Martinez, N., Martin, L., Fontecilla-Camps, J.C.
Deposit date:2009-04-17
Release date:2009-07-21
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Introduction of methionines in the gas channel makes [NiFe] hydrogenase aero-tolerant
J.Am.Chem.Soc., 131, 2009
4OO9
  • Download 4oo9
  • View 4oo9
Molmil generated image of 4oo9
STRUCTURE OF THE HUMAN CLASS C GPCR METABOTROPIC GLUTAMATE RECEPTOR 5 TRANSMEMBRANE DOMAIN IN COMPLEX WITH THE NEGATIVE ALLOSTERIC MODULATOR MAVOGLURANT
Descriptor:Metabotropic glutamate receptor 5, Lysozyme, Metabotropic glutamate receptor 5 chimera, ...
Authors:Dore, A.S., Okrasa, K., Patel, J.C., Serrano-Vega, M., Bennett, K., Cooke, R.M., Errey, J.C., Jazayeri, A., Khan, S., Tehan, B., Weir, M., Wiggin, G.R., Marshall, F.H.
Deposit date:2014-01-31
Release date:2014-07-02
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Nature, 511, 2014
5GYJ
  • Download 5gyj
  • View 5gyj
Molmil generated image of 5gyj
STRUCTURE OF CATALYTICALLY ACTIVE SORTASE FROM CLOSTRIDIUM DIFFICILE
Descriptor:Putative peptidase C60B, sortase B
Authors:Yin, J.-C., Fei, C.-H., Hsiao, Y.-Y., Nix, J.C., Huang, I.-H., Wang, S.
Deposit date:2016-09-22
Release date:2017-01-04
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural Insights into Substrate Recognition by Clostridium difficile Sortase.
Front Cell Infect Microbiol, 6, 2016
6MDR
  • Download 6mdr
  • View 6mdr
Molmil generated image of 6mdr
CRYO-EM STRUCTURE OF THE CERU+32/GFP-17 PROTOMER
Descriptor:Ceru+32, GFP-17
Authors:Simon, A.J., Zhou, Y., Ramasubramani, V., Glaser, J., Pothukuchy, A., Golihar, J., Gerberich, J.C., Leggere, J.C., Morrow, B.R., Jung, C., Glotzer, S.C., Taylor, D.W., Ellington, A.D.
Deposit date:2018-09-05
Release date:2019-01-23
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Supercharging enables organized assembly of synthetic biomolecules.
Nat Chem, 11, 2019
8EST
  • Download 8est
  • View 8est
Molmil generated image of 8est
REACTION OF PORCINE PANCREATIC ELASTASE WITH 7-SUBSTITUTED 3-ALKOXY-4-CHLOROISOCOUMARINS: DESIGN OF POTENT INHIBITORS USING THE CRYSTAL STRUCTURE OF THE COMPLEX FORMED WITH 4-CHLORO-3-ETHOXY-7-GUANIDINO-ISOCOUMARIN
Descriptor:PORCINE PANCREATIC ELASTASE, SULFATE ION, CALCIUM ION, ...
Authors:Radhakrishnan, R., Powers, J.C., Meyerjunior, E.F.
Deposit date:1990-02-21
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin.
Biochemistry, 29, 1990
9EST
  • Download 9est
  • View 9est
Molmil generated image of 9est
STRUCTURAL STUDY OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH 7-AMINO-3-(2-BROMOETHOXY)-4-CHLOROISOCOUMARIN AS A NONREACTIVATABLE DOUBLY COVALENT ENZYME-INHIBITOR COMPLEX
Descriptor:PORCINE PANCREATIC ELASTASE, SULFATE ION, CALCIUM ION, ...
Authors:Radhakrishnan, R., Powers, J.C., Meyer Jr., E.F.
Deposit date:1991-01-14
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex.
Biochemistry, 30, 1991
1ANF
  • Download 1anf
  • View 1anf
Molmil generated image of 1anf
MALTODEXTRIN BINDING PROTEIN WITH BOUND MALTOSE
Descriptor:MALTODEXTRIN-BINDING PROTEIN, ALPHA-D-GLUCOSE
Authors:Spurlino, J.C., Quiocho, F.A.
Deposit date:1997-06-25
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor.
Structure, 5, 1997
1ASY
  • Download 1asy
  • View 1asy
Molmil generated image of 1asy
CLASS II AMINOACYL TRANSFER RNA SYNTHETASES: CRYSTAL STRUCTURE OF YEAST ASPARTYL-TRNA SYNTHETASE COMPLEXED WITH TRNA ASP
Descriptor:T-RNA (75-MER), ASPARTYL-tRNA SYNTHETASE
Authors:Ruff, M., Cavarelli, J., Rees, B., Krishnaswamy, S., Thierry, J.C., Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).
Science, 252, 1991
1ASZ
  • Download 1asz
  • View 1asz
Molmil generated image of 1asz
THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION
Descriptor:T-RNA (75-MER), ASPARTYL-tRNA SYNTHETASE, ADENOSINE-5'-TRIPHOSPHATE
Authors:Cavarelli, J., Rees, B., Thierry, J.C., Moras, D.
Deposit date:1995-01-19
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
EMBO J., 13, 1994
1ICM
  • Download 1icm
  • View 1icm
Molmil generated image of 1icm
ESCHERICHIA COLI-DERIVED RAT INTESTINAL FATTY ACID BINDING PROTEIN WITH BOUND MYRISTATE AT 1.5 A RESOLUTION AND I-FABPARG106-->GLN WITH BOUND OLEATE AT 1.74 A RESOLUTION
Descriptor:INTESTINAL FATTY ACID BINDING PROTEIN, MYRISTIC ACID
Authors:Eads, J.C., Sacchettini, J.C., Kromminga, A., Gordon, J.I.
Deposit date:1993-09-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106-->Gln with bound oleate at 1.74 A resolution.
J.Biol.Chem., 268, 1993
1ICN
  • Download 1icn
  • View 1icn
Molmil generated image of 1icn
ESCHERICHIA COLI-DERIVED RAT INTESTINAL FATTY ACID BINDING PROTEIN WITH BOUND MYRISTATE AT 1.5 A RESOLUTION AND I-FABPARG106-->GLN WITH BOUND OLEATE AT 1.74 A RESOLUTION
Descriptor:INTESTINAL FATTY ACID BINDING PROTEIN, OLEIC ACID
Authors:Eads, J.C., Sacchettini, J.C., Kromminga, A., Gordon, J.I.
Deposit date:1993-09-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABPArg106-->Gln with bound oleate at 1.74 A resolution.
J.Biol.Chem., 268, 1993
1KZW
  • Download 1kzw
  • View 1kzw
Molmil generated image of 1kzw
SOLUTION STRUCTURE OF HUMAN INTESTINAL FATTY ACID BINDING PROTEIN
Descriptor:INTESTINAL FATTY ACID-BINDING PROTEIN (A54)
Authors:Zhang, F., Luecke, C., Baier, L.J., Sacchettini, J.C., Hamilton, J.A.
Deposit date:2002-02-08
Release date:2003-07-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism
Biochemistry, 42, 2003