5LY3
| |
5LY5
| |
5MW1
| |
6DYS
| C-terminal condensation domain of Ebony in complex with beta-alanyl-dopamine | Descriptor: | CALCIUM ION, Ebony, N-[2-(3,4-dihydroxyphenyl)ethyl]-beta-alaninamide | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6DYN
| C-terminal condensation domain of Ebony in complex with Histamine | Descriptor: | CALCIUM ION, Ebony, HISTAMINE | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6DYO
| C-terminal condensation domain of Ebony in complex with L-Dopamine | Descriptor: | CALCIUM ION, Ebony, L-DOPAMINE | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6DYM
| C-terminal condensation domain of Ebony | Descriptor: | CALCIUM ION, Ebony | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
6DYR
| C-terminal condensation domain of Ebony in complex with Carcinine | Descriptor: | Ebony, N-[2-(1H-imidazol-5-yl)ethyl]-beta-alaninamide | Authors: | Izore, T, Tailhades, J, Hansen, M.H, Kaczmarski, J.A, Jackson, C.J, Cryle, M.J. | Deposit date: | 2018-07-02 | Release date: | 2019-01-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Drosophila melanogasternonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
2WW8
| Structure of the pilus adhesin (RrgA) from Streptococcus pneumoniae | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CELL WALL SURFACE ANCHOR FAMILY PROTEIN, ... | Authors: | Izore, T, Contreras-Martel, C, El-Mortaji, L, Manzano, C, Terrasse, R, Vernet, T, Di-Guilmi, A.M, Dessen, A. | Deposit date: | 2009-10-22 | Release date: | 2010-01-19 | Last modified: | 2013-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis of Host Cell Recognition by the Pilus Adhesin from Streptococcus Pneumoniae Structure, 18, 2010
|
|
7KW0
| Non-ribosomal didomain (stabilised glycine-PCP-C) acceptor bound state | Descriptor: | N-{2-[(2-aminoethyl)sulfanyl]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, PCP-C didomain | Authors: | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | Deposit date: | 2020-11-29 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
|
|
7KW3
| Non Ribosomal PCP domain | Descriptor: | PCP domain, SULFATE ION | Authors: | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | Deposit date: | 2020-11-29 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
|
|
7KVW
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state | Descriptor: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | Authors: | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | Deposit date: | 2020-11-29 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
|
|
7KW2
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G | Descriptor: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | Authors: | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | Deposit date: | 2020-11-29 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
|
|
2YJL
| Structural characterization of a secretin pilot protein from the type III secretion system (T3SS) of Pseudomonas aeruginosa | Descriptor: | EXOENZYME S SYNTHESIS PROTEIN B, NICKEL (II) ION, SULFATE ION | Authors: | Izore, T, Perdu, C, Job, V, Atree, I, Faudry, E, Dessen, A. | Deposit date: | 2011-05-20 | Release date: | 2011-08-10 | Last modified: | 2011-10-12 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural Characterization and Membrane Localization of Exsb from the Type III Secretion System (T3Ss) of Pseudomonas Aeruginosa J.Mol.Biol., 413, 2011
|
|
4CJ7
| Structure of Crenactin, an archeal actin-like protein | Descriptor: | ACTIN/ACTIN FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE | Authors: | Izore, T, Duman, R.E, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2013-12-19 | Release date: | 2014-01-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crenactin from Pyrobaculum Calidifontis is Closely Related to Actin in Structure and Forms Steep Helical Filaments. FEBS Lett., 588, 2014
|
|
6M7L
| Complex of OxyA with the X-domain from GPA biosynthesis | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase, Putative non-ribosomal peptide synthetase | Authors: | Greule, A, Izore, T, Tailhades, J, Peschke, M, Schoppet, M, Ahmed, I, Kulik, A, Adamek, M, Ziemert, N, De Voss, J, Stegmann, E, Cryle, M.J. | Deposit date: | 2018-08-20 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.648297 Å) | Cite: | Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nat Commun, 10, 2019
|
|
8G3J
| |
8G3I
| |
6UW7
| The crystal structure of FbiA from Mycobacterium smegmatis, Dehydro-F420-0 bound form | Descriptor: | 2-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[2,4,8-tris(oxidanylidene)-1,9-dihydropyrimido[4,5-b]quinolin-10-yl]pentoxy]phosphoryl]oxyprop-2-enoic acid, CALCIUM ION, GLYCEROL, ... | Authors: | Grinter, R, Gillett, D, Cordero, P.R.F, Izore, T, Greening, C. | Deposit date: | 2019-11-04 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.342 Å) | Cite: | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
|
|
7TTA
| P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation, attenuated beam | Descriptor: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase | Authors: | Greule, A, Izore, T, Cryle, M.J. | Deposit date: | 2022-02-01 | Release date: | 2022-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
|
|
7TTO
| |
7TTP
| P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation | Descriptor: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase | Authors: | Greule, A, Izore, T, Cryle, M.J. | Deposit date: | 2022-02-01 | Release date: | 2022-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
|
|
7TTB
| P450 (OxyA) from kistamicin biosynthesis, Y99F mutant | Descriptor: | GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase | Authors: | Greule, A, Izore, T, Cryle, M.J. | Deposit date: | 2022-02-01 | Release date: | 2022-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.801592 Å) | Cite: | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
|
|
7TTQ
| P450 (OxyA) from kistamicin biosynthesis, imidazole complex | Descriptor: | GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Greule, A, Izore, T, Cryle, M.J. | Deposit date: | 2022-02-01 | Release date: | 2022-05-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
|
|
2W1J
| CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) from Streptococcus pneumoniae | Descriptor: | GLYCEROL, PUTATIVE SORTASE | Authors: | Manzano, C, Contreras-Martel, C, El Mortaji, L, Izore, T, Fenel, D, Vernet, T, Schoehn, G, Di Guilmi, A.M, Dessen, A. | Deposit date: | 2008-10-17 | Release date: | 2008-12-23 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Sortase-Mediated Pilus Fiber Biogenesis in Streptococcus Pneumoniae. Structure, 16, 2008
|
|