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5XE8
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CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF STREPTOCOCCUS MUTANS COMA
Descriptor:Putative ABC transporter, ATP-binding protein ComA, DI(HYDROXYETHYL)ETHER
Authors:Ishii, S., Fukui, K., Yokoshima, S., Kumagai, K., Beniyama, Y., Kodama, T., Fukuyama, T., Okabe, T., Nagano, T., Kojima, H., Yano, T.
Deposit date:2017-04-03
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway
Sci Rep, 7, 2017
5XE9
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE PEPTIDASE DOMAIN OF STREPTOCOCCUS MUTANS COMA WITH A SMALL MOLECULE INHIBITOR.
Descriptor:Putative ABC transporter, ATP-binding protein ComA, [(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl ~{N}-propylcarbamate
Authors:Ishii, S., Fukui, K., Yokoshima, S., Kumagai, K., Beniyama, Y., Kodama, T., Fukuyama, T., Okabe, T., Nagano, T., Kojima, H., Yano, T.
Deposit date:2017-04-03
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway
Sci Rep, 7, 2017
3VX4
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CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAIN OF S. MUTANS COMA, A BIFUNCTIONAL ATP-BINDING CASSETTE TRANSPORTER INVOLVED IN THE QUORUM-SENSING PATHWAY
Descriptor:Putative ABC transporter, ATP-binding protein ComA, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Ishii, S., Yano, T., Okamoto, A., Murakawa, T., Hayashi, H.
Deposit date:2012-09-11
Release date:2013-04-17
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Boundary of the Nucleotide-Binding Domain of Streptococcus ComA Based on Functional and Structural Analysis
Biochemistry, 52, 2013
3K8U
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CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF STREPTOCOCCUS COMA, A BI-FUNCTIONAL ABC TRANSPORTER INVOLVED IN QUORUM SENSING PATHWAY
Descriptor:Putative ABC transporter, ATP-binding protein ComA
Authors:Ishii, S., Yano, T., Ebihara, A., Okamoto, A., Manzoku, M., Hayashi, H.
Deposit date:2009-10-14
Release date:2010-02-23
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the peptidase domain of Streptococcus ComA, a bifunctional ATP-binding cassette transporter involved in the quorum-sensing pathway
J.Biol.Chem., 285, 2010
5GUX
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CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH XENON
Descriptor:Antibody fab fragment light chain, Antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Ishii, S., Terasaka, E., Sugimoto, H., Shiro, Y., Tosha, T.
Deposit date:2016-08-31
Release date:2017-08-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Dynamics of nitric oxide controlled by protein complex in bacterial system.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1MBE
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1
Descriptor:MYB PROTO-ONCOGENE PROTEIN
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-07-31
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBF
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 1
Descriptor:MYB PROTO-ONCOGENE PROTEIN
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-07-31
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBG
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2
Descriptor:MYB PROTO-ONCOGENE PROTEIN
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-07-31
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBH
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2
Descriptor:C-MYB
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-09-15
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBJ
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
Descriptor:MYB PROTO-ONCOGENE PROTEIN
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-07-31
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1MBK
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MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
Descriptor:MYB PROTO-ONCOGENE PROTEIN
Authors:Ogata, K., Morikawa, S., Nakamura, H., Hojo, H., Yoshimura, S., Zhang, R., Aimoto, S., Ametani, Y., Hirata, Z., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-05-19
Release date:1995-07-31
Last modified:2012-02-29
Method:SOLUTION NMR
Cite:Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb.
Nat.Struct.Biol., 2, 1995
1BHI
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STRUCTURE OF TRANSACTIVATION DOMAIN OF CRE-BP1/ATF-2, NMR, 20 STRUCTURES
Descriptor:CRE-BP1
Authors:Nagadoi, A., Nakazawa, K., Uda, H., Maekawa, T., Ishii, S., Nishimura, Y.
Deposit date:1998-06-09
Release date:1999-06-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the transactivation domain of ATF-2 comprising a zinc finger-like subdomain and a flexible subdomain.
J.Mol.Biol., 287, 1999
1MSE
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SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES
Descriptor:DNA (5'-D(*CP*CP*TP*AP*AP*CP*TP*GP*AP*CP*AP*CP*AP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*TP*GP*TP*GP*TP*CP*AP*GP*TP*TP*AP*GP*G)-3'), C-Myb DNA-Binding Domain
Authors:Ogata, K., Morikawa, S., Nakamura, H., Sekikawa, A., Inoue, T., Kanai, H., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-01-24
Release date:1995-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices.
Cell(Cambridge,Mass.), 79, 1994
1MSF
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SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES
Descriptor:DNA (5'-D(*CP*CP*TP*AP*AP*CP*TP*GP*AP*CP*AP*CP*AP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*TP*GP*TP*GP*TP*CP*AP*GP*TP*TP*AP*GP*G)-3'), C-Myb DNA-Binding Domain
Authors:Ogata, K., Morikawa, S., Nakamura, H., Sekikawa, A., Inoue, T., Kanai, H., Sarai, A., Ishii, S., Nishimura, Y.
Deposit date:1995-01-24
Release date:1995-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices.
Cell(Cambridge,Mass.), 79, 1994
3VJK
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CRYSTAL STRUCTURE OF HUMAN DEPIPTIDYL PEPTIDASE IV (DPP-4) IN COMPLEX WITH MP-513
Descriptor:Dipeptidyl peptidase 4, {(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-yl}(1,3-thiazolidin-3-yl)methanone, N-ACETYL-D-GLUCOSAMINE
Authors:Akahoshi, F., Kishida, H., Miyaguchi, I., Yoshida, T., Ishii, S.
Deposit date:2011-10-24
Release date:2012-10-24
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem., 20, 2012
3VJL
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CRYSTAL STRUCTURE OF HUMAN DEPIPTIDYL PEPTIDASE IV (DPP-4) IN COMPLEX WITH A PROLYLTHIAZOLIDINE INHIBITOR #2
Descriptor:Dipeptidyl peptidase 4, [(2S,4S)-4-{4-[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]piperidin-1-yl}pyrrolidin-2-yl](1,3-thiazolidin-3-yl)methanone, N-ACETYL-D-GLUCOSAMINE
Authors:Akahoshi, F., Kishida, H., Miyaguchi, I., Yoshida, T., Ishii, S.
Deposit date:2011-10-24
Release date:2012-10-24
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem., 20, 2012
5AZE
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FAB FRAGMENT OF CALCIUM-DEPENDENT ANTIGEN BINDING ANTIBODY, 6RL#9
Descriptor:6RL#9 FAB LIGHT CHAIN, 6RL#9 FAB HEAVY CHAIN, CALCIUM ION
Authors:Kadono, S., Hironiwa, N., Ishii, S., Igawa, T., Hattori, K.
Deposit date:2015-10-02
Release date:2015-11-11
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation
Mabs, 8, 2016
3WFC
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REDUCED AND CARBONMONOXIDE-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
3WFD
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REDUCED AND ACETALDOXIME-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
3WFE
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REDUCED AND CYANIDE-BOUND CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
3WFB
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REDUCED CYTOCHROME C-DEPENDENT NITRIC OXIDE REDUCTASE (CNOR) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH ANTIBODY FRAGMENT
Descriptor:antibody fab fragment light chain, antibody fab fragment heavy chain, Nitric oxide reductase subunit B, ...
Authors:Sato, N., Ishii, S., Hino, T., Sugimoto, H., Fukumori, Y., Shiro, Y., Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes
Proteins, 2013
1H89
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CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX2
Descriptor:CAAT/ENHANCER BINDING PROTEIN BETA, MYB PROTO-ONCOGENE PROTEIN, DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ...
Authors:Tahirov, T.H., Ogata, K.
Deposit date:2001-01-30
Release date:2002-01-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Cell(Cambridge,Mass.), 108, 2002
1H8A
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CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX3
Descriptor:CAAT/ENHANCER BINDING PROTEIN BETA, MYB TRANSFORMING PROTEIN, DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ...
Authors:Tahirov, T.H., Ogata, K.
Deposit date:2001-01-31
Release date:2002-01-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Cell(Cambridge,Mass.), 108, 2002
5GUW
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COMPLEX OF CYTOCHROME CD1 NITRITE REDUCTASE AND NITRIC OXIDE REDUCTASE IN DENITRIFICATION OF PSEUDOMONAS AERUGINOSA
Descriptor:Nitric oxide reductase subunit C, Nitric oxide reductase subunit B, Nitrite reductase, ...
Authors:Terasaka, E., Sugimoto, H., Shiro, Y., Tosha, T.
Deposit date:2016-08-31
Release date:2017-08-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Dynamics of nitric oxide controlled by protein complex in bacterial system
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1H88
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CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX1
Descriptor:CCAAT/ENHANCER BINDING PROTEIN BETA, MYB PROTO-ONCOGENE PROTEIN, DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ...
Authors:Tahirov, T.H., Ogata, K.
Deposit date:2001-01-29
Release date:2002-01-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Cell(Cambridge,Mass.), 108, 2002
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