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1LR7
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CRYSTAL STRUCTURE OF FS1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN, COMPLEXED WITH THE HEPARIN ANALOGUE SUCROSE OCTASULPHATE (SOS)
Descriptor:follistatin, SULFATE ION
Authors:Innis, C.A., Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1LR8
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CRYSTAL STRUCTURE OF FS1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN, COMPLEXED WITH THE HEPARIN ANALOGUE D-MYO-INOSITOL HEXASULPHATE (INS6S)
Descriptor:Follistatin, D-MYO-INOSITOL-HEXASULPHATE
Authors:Innis, C.A., Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1LR9
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STRUCTURE OF FS1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN
Descriptor:Follistatin
Authors:Innis, C.A., Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1VY4
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN THE PRE-ATTACK STATE OF PEPTIDE BOND FORMATION CONTAINING ACYLATED TRNA-SUBSTRATES IN THE A AND P SITES.
Descriptor:16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Polikanov, Y.S., Steitz, T.A., Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY5
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN THE POST-CATALYSIS STATE OF PEPTIDE BOND FORMATION CONTAINING DIPEPTYDIL-TRNA IN THE A SITE AND DEACYLATED TRNA IN THE P SITE.
Descriptor:16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Polikanov, Y.S., Steitz, T.A., Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY6
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN THE PRE-ATTACK STATE OF PEPTIDE BOND FORMATION CONTAINING SHORT SUBSTRATE-MIMIC CYTIDINE-PUROMYCIN IN THE A SITE AND ACYLATED TRNA IN THE P SITE.
Descriptor:16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Polikanov, Y.S., Steitz, T.A., Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY7
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN THE PRE-ATTACK STATE OF PEPTIDE BOND FORMATION CONTAINING SHORT SUBSTRATE-MIMIC CYTIDINE-CYTIDINE-PUROMYCIN IN THE A SITE AND ACYLATED TRNA IN THE P SITE.
Descriptor:16S Ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Polikanov, Y.S., Steitz, T.A., Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
3GNA
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CRYSTAL STRUCTURE OF THE RAG1 NONAMER-BINDING DOMAIN WITH DNA
Descriptor:V(D)J recombination-activating protein 1, 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3'
Authors:Yin, F.F., Bailey, S., Innis, C.A., Steitz, T.A., Schatz, D.G.
Deposit date:2009-03-16
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Nat.Struct.Mol.Biol., 16, 2009
3GNB
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CRYSTAL STRUCTURE OF THE RAG1 NONAMER-BINDING DOMAIN WITH DNA
Descriptor:V(D)J recombination-activating protein 1, 5'-D(*AP*AP*TP*TP*TP*TP*CP*AP*GP*AP*AP*AP*CP*C)-3', 5'-D(*AP*GP*GP*TP*TP*TP*CP*TP*GP*AP*AP*AP*AP*C)-3'
Authors:Yin, F.F., Bailey, S., Innis, C.A., Steitz, T.A., Schatz, D.G.
Deposit date:2009-03-16
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis.
Nat.Struct.Mol.Biol., 16, 2009
3J9W
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CRYO-EM STRUCTURE OF THE BACILLUS SUBTILIS MIFM-STALLED RIBOSOME COMPLEX
Descriptor:16S ribosomal RNA, 30S ribosomal protein uS2, 30S ribosomal protein uS3, ...
Authors:Sohmen, D., Chiba, S., Shimokawa-Chiba, N., Innis, C.A., Berninghausen, O., Beckmann, R., Ito, K., Wilson, D.N.
Deposit date:2015-03-16
Release date:2015-04-29
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling.
Nat Commun, 6, 2015
4V5H
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E.COLI 70S RIBOSOME STALLED DURING TRANSLATION OF TNAC LEADER PEPTIDE.
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Seidelt, B., Innis, C.A., Wilson, D.N., Gartmann, M., Armache, J., Villa, E., Trabuco, L.G., Becker, T., Mielke, T., Schulten, K., Steitz, T.A., Beckmann, R.
Deposit date:2009-10-26
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insight into nascent polypeptide chain-mediated translational stalling.
Science, 326, 2009
4V7W
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STRUCTURE OF THE THERMUS THERMOPHILUS RIBOSOME COMPLEXED WITH CHLORAMPHENICOL.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A.
Deposit date:2010-08-16
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7X
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STRUCTURE OF THE THERMUS THERMOPHILUS RIBOSOME COMPLEXED WITH ERYTHROMYCIN.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A.
Deposit date:2010-08-17
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7Y
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STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH AZITHROMYCIN.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A.
Deposit date:2010-08-18
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4V7Z
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STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH TELITHROMYCIN.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Bulkley, D.P., Innis, C.A., Blaha, G., Steitz, T.A.
Deposit date:2010-08-18
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc.Natl.Acad.Sci.USA, 107, 2010
4ZER
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CRYSTAL STRUCTURE OF THE ONC112 ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23s ribosomal RNA, 5s ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Nguyen, F., Antunes, S., Perebaskine, N., Graf, M., Arenz, S., Inampudi, K.K., Douat, C., Guichard, G., Wilson, D.N., Innis, C.A.
Deposit date:2015-04-20
Release date:2015-05-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Nat.Struct.Mol.Biol., 22, 2015
5F8K
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CRYSTAL STRUCTURE OF THE BAC7(1-16) ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-09
Release date:2016-02-03
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5FDU
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CRYSTAL STRUCTURE OF THE METALNIKOWIN I ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5FDV
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CRYSTAL STRUCTURE OF THE PYRRHOCORICIN ANTIMICROBIAL PEPTIDE BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Seefeldt, A.C., Graf, M., Perebaskine, N., Nguyen, F., Arenz, S., Mardirossian, M., Scocchi, M., Wilson, D.N., Innis, C.A.
Deposit date:2015-12-16
Release date:2016-01-27
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Nucleic Acids Res., 44, 2016
5JTE
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CRYO-EM STRUCTURE OF AN ERMBL-STALLED RIBOSOME IN COMPLEX WITH A-, P-, AND E-TRNA
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Arenz, S., Bock, L.V., Graf, M., Innis, C.A., Beckmann, R., Grubmueller, H., Vaiana, A.C., Wilson, D.N.
Deposit date:2016-05-09
Release date:2016-07-20
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5JU8
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CRYO-EM STRUCTURE OF AN ERMBL-STALLED RIBOSOME IN COMPLEX WITH P-, AND E-TRNA
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Arenz, S., Bock, L.V., Graf, M., Innis, C.A., Beckmann, R., Grubmueller, H., Vaiana, A.C., Wilson, D.N.
Deposit date:2016-05-10
Release date:2016-07-20
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
6FKR
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CRYSTAL STRUCTURE OF THE DOLPHIN PROLINE-RICH ANTIMICROBIAL PEPTIDE TUR1A BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Mardirossian, M., Perebaskine, N., Benincasa, M., Gambato, S., Hofmann, S., Huter, P., Muller, C., Hilpert, K., Innis, C.A., Tossi, A., Wilson, D.N.
Deposit date:2018-01-24
Release date:2018-03-28
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome.
Cell Chem Biol, 25, 2018