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4I89
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BU of 4i89 by Molmil
Crystal structure of transthyretin in complex with diflunisal at acidic pH
Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
Authors:Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R.
Deposit date:2012-12-03
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
4I87
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BU of 4i87 by Molmil
Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH
Descriptor: 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin
Authors:Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R.
Deposit date:2012-12-03
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
4I85
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BU of 4i85 by Molmil
Crystal structure of transthyretin in complex with CHF5074 at neutral pH
Descriptor: 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin
Authors:Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R.
Deposit date:2012-12-03
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
6R66
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BU of 6r66 by Molmil
Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue
Descriptor: 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R67
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BU of 6r67 by Molmil
Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue
Descriptor: (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R68
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BU of 6r68 by Molmil
Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue
Descriptor: (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-26
Release date:2019-09-11
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
6R6I
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BU of 6r6i by Molmil
Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue
Descriptor: 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin
Authors:Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G.
Deposit date:2019-03-27
Release date:2019-09-11
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (1.467 Å)
Cite:Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019

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