Author results

1CCZ
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CRYSTAL STRUCTURE OF THE CD2-BINDING DOMAIN OF CD58 (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3) AT 1.8-A RESOLUTION
Descriptor:PROTEIN (CD58), N-ACETYL-D-GLUCOSAMINE
Authors:Ikemizu, S., Sparks, L.M., Van Der Merwe, P.A., Harlos, K., Stuart, D.I., Jones, E.Y., Davis, S.J.
Deposit date:1999-03-02
Release date:1999-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
1DR9
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CRYSTAL STRUCTURE OF A SOLUBLE FORM OF B7-1 (CD80)
Descriptor:T LYMPHOCYTE ACTIVATION ANTIGEN, N-ACETYL-D-GLUCOSAMINE
Authors:Ikemizu, S., Jones, E.Y., Stuart, D.I., Davis, S.J.
Deposit date:2000-01-06
Release date:2000-01-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and dimerization of a soluble form of B7-1.
Immunity, 12, 2000
2M2D
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HUMAN PROGRAMMED CELL DEATH 1 RECEPTOR
Descriptor:Programmed cell death protein 1
Authors:Veverka, V., Cheng, X., Waters, L.C., Muskett, F.W., Morgan, S., Lesley, A., Griffiths, M., Stubberfield, C., Griffin, R., Henry, A.J., Robinson, M.K., Jansson, A., Ladbury, J.E., Ikemizu, S., Davis, S.J., Carr, M.D.
Deposit date:2012-12-18
Release date:2013-02-27
Last modified:2013-05-15
Method:SOLUTION NMR
Cite:Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
2Z3Q
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CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX
Descriptor:Interleukin-15, Interleukin-15 receptor alpha chain
Authors:Chirifu, M., Yamagata, Y., Davis, S.J., Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
2Z3R
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CRYSTAL STRUCTURE OF THE IL-15/IL-15RA COMPLEX
Descriptor:Interleukin-15, Interleukin-15 receptor alpha chain, GLYCEROL
Authors:Chirifu, M., Yamagata, Y., Davis, S.J., Ikemizu, S.
Deposit date:2007-06-05
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8, 2007
3A4E
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN (E54G)
Descriptor:Transthyretin, GLYCEROL, SULFATE ION
Authors:Miyata, M., Sato, T., Nakamura, T., Ikemizu, S., Yamagata, Y., Kai, H.
Deposit date:2009-07-06
Release date:2009-12-22
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
3A4F
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN (E54K)
Descriptor:Transthyretin, GLYCEROL, SULFATE ION
Authors:Miyata, M., Sato, T., Nakamura, T., Ikemizu, S., Yamagata, Y., Kai, H.
Deposit date:2009-07-06
Release date:2009-12-22
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
3NG5
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CRYSTAL STRUCTURE OF V30M TRANSTHYRETIN COMPLEXED WITH (-)-EPIGALLOCATECHIN GALLATE (EGCG)
Descriptor:Transthyretin, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL
Authors:Miyata, M., Nakamura, T., Ikemizu, S., Chirifu, M., Yamagata, Y., Kai, H.
Deposit date:2010-06-11
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site
Biochemistry, 2010
1DTQ
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-1 (PETT131A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-NITRILOMETHYL-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-03-20
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1DTT
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-04-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1EPF
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CRYSTAL STRUCTURE OF THE TWO N-TERMINAL IMMUNOGLOBULIN DOMAINS OF THE NEURAL CELL ADHESION MOLECULE (NCAM)
Descriptor:PROTEIN (NEURAL CELL ADHESION MOLECULE), CALCIUM ION
Authors:Kasper, C., Rasmussen, H., Kastrup, J.S., Ikemizu, S., Jones, E.Y., Berezin, V., Bock, E., Larsen, I.K.
Deposit date:2000-03-29
Release date:2000-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of cell-cell adhesion by NCAM.
Nat.Struct.Biol., 7, 2000
1EVS
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CRYSTAL STRUCTURE OF HUMAN ONCOSTATIN M
Descriptor:ONCOSTATIN M
Authors:Deller, M.C., Hudson, K.R., Ikemizu, S., Bravo, J., Jones, E.Y., Heath, J.K.
Deposit date:2000-04-20
Release date:2000-09-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure and functional dissection of the cytostatic cytokine oncostatin M.
Structure Fold.Des., 8, 2000
1H15
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X-RAY CRYSTAL STRUCTURE OF HLA-DRA1*0101/DRB5*0101 COMPLEXED WITH A PEPTIDE FROM EPSTEIN BARR VIRUS DNA POLYMERASE
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DR BETA 1 CHAIN, ...
Authors:Lang, H., Jacobsen, H., Ikemizu, S., Andersson, C., Harlos, K., Madsen, L., Hjorth, P., Sondergaard, L., Svejgaard, A., Wucherpfennig, K., Stuart, D.I., Bell, J.I., Jones, E.Y., Fugger, L.
Deposit date:2002-07-02
Release date:2002-10-03
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
2DRU
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CRYSTAL STRUCTURE AND BINDING PROPERTIES OF THE CD2 AND CD244 (2B4) BINDING PROTEIN, CD48
Descriptor:chimera of CD48 antigen and T-cell surface antigen CD2, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Evans, E.J., Ikemizu, S., Davis, S.J.
Deposit date:2006-06-15
Release date:2006-07-04
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and Binding Properties of the CD2 and CD244 (2B4)-binding Protein, CD48
J.Biol.Chem., 281, 2006
3OSK
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CRYSTAL STRUCTURE OF HUMAN CTLA-4 APO HOMODIMER
Descriptor:Cytotoxic T-lymphocyte protein 4, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Yu, C., Sonnen, A.F.-P., Ikemizu, S., Stuart, D.I., Gilbert, R.J.C., Davis, S.J.
Deposit date:2010-09-09
Release date:2010-12-08
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering
J.Biol.Chem., 286, 2011
1FRR
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CRYSTAL STRUCTURE OF [2FE-2S] FERREDOXIN I FROM EQUISETUM ARVENSE AT 1.8 ANGSTROMS RESOLUTION
Descriptor:FERREDOXIN I, FE2/S2 (INORGANIC) CLUSTER
Authors:Tsukihara, T.
Deposit date:1993-09-24
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of [2Fe-2S] ferredoxin I from Equisetum arvense at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
6IJY
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/C87A/C104S MUTANT) IN COMPLEX WITH 8-OXO-DGTP DETERMINED USING A CRYSTAL OBTAINED UNDER MICROGRAVITY
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION, ...
Authors:Nakamura, T., Yamagata, Y.
Deposit date:2018-10-12
Release date:2019-02-20
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:X-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity.
Int. J. Microgravity Sci. Appl., 36, 2019
5GHI
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K MUTANT) IN COMPLEX WITH 8-OXO-DGTP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.211 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHJ
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K MUTANT) IN COMPLEX WITH 2-OXO-DATP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHM
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/D120N MUTANT) IN COMPLEX WITH 8-OXO-DGTP AT PH 7.0
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHN
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/D120N MUTANT) IN COMPLEX WITH 2-OXO-DATP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHO
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/D120A MUTANT) IN COMPLEX WITH 8-OXO-DGTP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, SODIUM ION, ...
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.191 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHP
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/D120A MUTANT) IN COMPLEX WITH 2-OXO-DATP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.192 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5GHQ
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/D120A MUTANT) IN COMPLEX WITH 2-OXO-DATP UNDER HIGH CONCENTRATIONS OF 2-OXO-DATP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-06-20
Release date:2017-01-04
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.181 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5WS7
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CRYSTAL STRUCTURE OF HUMAN MTH1(G2K/C87A/C104S MUTANT) IN COMPLEX WITH 2-OXO-DATP
Descriptor:7,8-dihydro-8-oxoguanine triphosphatase, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate, SODIUM ION
Authors:Nakamura, T., Waz, S., Hirata, K., Nakabeppu, Y., Yamagata, Y.
Deposit date:2016-12-05
Release date:2017-01-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
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