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5UBQ
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BU of 5ubq by Molmil
Cryo-EM structure of ciliary microtubule doublet
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ichikawa, M, Liu, D, Kastritis, P.L, Basu, K, Bui, K.H.
Deposit date:2016-12-21
Release date:2017-05-10
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins.
Nat Commun, 8, 2017
5UCY
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BU of 5ucy by Molmil
Cryo-EM map of protofilament of microtubule doublet
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ichikawa, M, Liu, D, Kastritis, P.L, Basu, K, Bui, K.H.
Deposit date:2016-12-22
Release date:2017-05-10
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins.
Nat Commun, 8, 2017
6U0T
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BU of 6u0t by Molmil
Protofilament Ribbon Flagellar Proteins Rib43a-S
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H.
Deposit date:2019-08-14
Release date:2019-09-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6U0H
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BU of 6u0h by Molmil
Tubulin lattice of the ciliary doublet microtubule from Tetrahymena thermophila
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H.
Deposit date:2019-08-14
Release date:2019-09-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
6U0U
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BU of 6u0u by Molmil
Protofilament Ribbon Flagellar Proteins Rib43a-L
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H.
Deposit date:2019-08-14
Release date:2019-09-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
3Q2Z
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BU of 3q2z by Molmil
Human Squalene synthase in complex with N-[(3R,5S)-7-Chloro-5-(2,3-dimethoxyphenyl)-1-neopentyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-acetyl]-L-aspartic acid
Descriptor: N-{[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]acetyl}-L-aspartic acid, PHOSPHATE ION, Squalene synthase
Authors:Suzuki, M, Shimizu, H, Katakura, S, Yamazaki, K, Higashihashi, N, Ichikawa, M, Yokomizo, A, Itoh, M, Sugita, K, Usui, H.
Deposit date:2010-12-21
Release date:2011-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
Bioorg.Med.Chem., 19, 2011
3Q30
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BU of 3q30 by Molmil
Human Squalene synthase in complex with (2R,3R)-2-Carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid
Descriptor: (2R,3R)-2-(carboxymethoxy)-4-{[5-(naphthalen-2-yl)pentyl]amino}-3-{[5-(naphthalen-2-yl)pentyl]oxy}-4-oxobutanoic acid, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Suzuki, M, Shimizu, H, Katakura, S, Yamazaki, K, Higashihashi, N, Ichikawa, M, Yokomizo, A, Itoh, M, Sugita, K, Usui, H.
Deposit date:2010-12-21
Release date:2011-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
Bioorg.Med.Chem., 19, 2011
3V66
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BU of 3v66 by Molmil
HUMAN SQUALENE SYNTHASE IN COMPLEX WITH 2-(1-{2-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetic acid
Descriptor: (1-{[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}piperidin-4-yl)acetic acid, PHOSPHATE ION, Squalene synthase
Authors:Suzuki, M, Ohtsuka, M, Ohki, H, Haginoya, N, Itoh, M, Sugita, K, Usui, H, Ichikawa, M, Higashihashi, N.
Deposit date:2011-12-18
Release date:2012-12-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of novel tricyclic compounds as squalene synthase inhibitors
Bioorg.Med.Chem., 20, 2012
3ASX
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BU of 3asx by Molmil
Human Squalene synthase in complex with 1-{4-[{4-chloro-2-[(2-chlorophenyl)(hydroxy)methyl]phenyl}(2,2-dimethylpropyl)amino]-4-oxobutanoyl}piperidine-3-carboxylic acid
Descriptor: (3R)-1-{4-[{4-chloro-2-[(S)-(2-chlorophenyl)(hydroxy)methyl]phenyl}(2,2-dimethylpropyl)amino]-4-oxobutanoyl}piperidine-3-carboxylic acid, PHOSPHATE ION, Squalene synthase
Authors:Shimizu, H, Suzuki, M, Katakura, S, Yamazaki, K, Higashihashi, N, Ichikawa, M, Yokomizo, A, Itoh, M, Sugita, K, Usui, H.
Deposit date:2010-12-22
Release date:2011-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
Bioorg.Med.Chem., 19, 2011
8J4C
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BU of 8j4c by Molmil
YeeE(TsuA)-YeeD(TsuB) complex for thiosulfate uptake
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Spirochaeta thermophila YeeE(TsuA)-YeeD(TsuB),UPF0033 domain-containing protein, SirA-like domain-containing protein (chimera), ...
Authors:Ikei, M, Miyazaki, R, Monden, K, Naito, Y, Takeuchi, A, Takahashi, Y.S, Tanaka, Y, Ichikawa, M, Tsukazaki, T.
Deposit date:2023-04-19
Release date:2024-03-27
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structure and function of YeeE-YeeD complex for sophisticated thiosulfate uptake
To Be Published
8K1R
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BU of 8k1r by Molmil
YeeE(TsuA)-YeeD(TsuB) complex for thiosulfate uptake
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Spirochaeta thermophila YeeE(TsuA)-YeeD(TsuB),UPF0033 domain-containing protein, SirA-like domain-containing protein (chimera)
Authors:Ikei, M, Miyazaki, R, Monden, K, Naito, Y, Takeuchi, A, Takahashi, Y.S, Tanaka, Y, Ichikawa, M, Tsukazaki, T.
Deposit date:2023-07-11
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and function of YeeE-YeeD complex for sophisticated thiosulfate uptake
To Be Published
7MOQ
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BU of 7moq by Molmil
The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ...
Authors:Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H.
Deposit date:2021-05-03
Release date:2021-07-14
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM.
Embo Rep., 22, 2021
4WVC
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BU of 4wvc by Molmil
Crystal structure of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8 in complex with Tris and D-glycerate
Descriptor: (2R)-2,3-DIHYDROXYPROPANOIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Miyazaki, T, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and substrate-binding mode of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8.
J.Struct.Biol., 190, 2015
4WVA
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BU of 4wva by Molmil
Crystal structure of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8 in complex with Tris
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Miyazaki, T, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Crystal structure and substrate-binding mode of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8.
J.Struct.Biol., 190, 2015
4WVB
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BU of 4wvb by Molmil
Crystal structure of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8 in complex with glucose
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Uncharacterized protein, ...
Authors:Miyazaki, T, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure and substrate-binding mode of GH63 mannosylglycerate hydrolase from Thermus thermophilus HB8.
J.Struct.Biol., 190, 2015
4XPO
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BU of 4xpo by Molmil
Crystal structure of a novel alpha-galactosidase from Pedobacter saltans
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-glucosidase
Authors:Miyazaki, T, Ishizaki, Y, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2015-01-17
Release date:2015-05-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical characterization of novel bacterial alpha-galactosidases belonging to glycoside hydrolase family 31
Biochem.J., 469, 2015
4XPR
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BU of 4xpr by Molmil
Crystal structure of the mutant D365A of Pedobacter saltans GH31 alpha-galactosidase
Descriptor: 1,2-ETHANEDIOL, Alpha-glucosidase
Authors:Miyazaki, T, Ishizaki, Y, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2015-01-17
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and biochemical characterization of novel bacterial alpha-galactosidases belonging to glycoside hydrolase family 31
Biochem.J., 469, 2015
4XPP
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BU of 4xpp by Molmil
Crystal structure of Pedobacter saltans GH31 alpha-galactosidase complexed with D-galactose
Descriptor: 1,2-ETHANEDIOL, Alpha-glucosidase, beta-D-galactopyranose
Authors:Miyazaki, T, Ishizaki, Y, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2015-01-17
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and biochemical characterization of novel bacterial alpha-galactosidases belonging to glycoside hydrolase family 31
Biochem.J., 469, 2015
4XPQ
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BU of 4xpq by Molmil
Crystal structure of Pedobacter saltans GH31 alpha-galactosidase complexed with L-fucose
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-glucosidase, ...
Authors:Miyazaki, T, Ishizaki, Y, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2015-01-17
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and biochemical characterization of novel bacterial alpha-galactosidases belonging to glycoside hydrolase family 31
Biochem.J., 469, 2015
4XPS
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BU of 4xps by Molmil
Crystal structure of the mutant D365A of Pedobacter saltans GH31 alpha-galactosidase complexed with p-nitrophenyl-alpha-galactopyranoside
Descriptor: 1,2-ETHANEDIOL, Alpha-glucosidase, P-NITROPHENOL, ...
Authors:Miyazaki, T, Ishizaki, Y, Ichikawa, M, Nishikawa, A, Tonozuka, T.
Deposit date:2015-01-17
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical characterization of novel bacterial alpha-galactosidases belonging to glycoside hydrolase family 31
Biochem.J., 469, 2015
6VE7
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BU of 6ve7 by Molmil
The inner junction complex of Chlamydomonas reinhardtii doublet microtubule
Descriptor: Cilia- and flagella-associated protein 20, FAP276, FAP52, ...
Authors:Khalifa, A.A.Z, Ichikawa, M, Bui, K.H.
Deposit date:2019-12-30
Release date:2020-02-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications.
Elife, 9, 2020
3W7W
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BU of 3w7w by Molmil
Crystal structure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose
Descriptor: CALCIUM ION, MAGNESIUM ION, Uncharacterized protein YgjK, ...
Authors:Miyazaki, T, Ichikawa, M, Yokoi, G, Kitaoka, M, Mori, H, Kitano, Y, Nishikawa, A, Tonozuka, T.
Deposit date:2013-03-08
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a bacterial glycoside hydrolase family 63 enzyme in complex with its glycosynthase product, and insights into the substrate specificity.
Febs J., 280, 2013
3W7X
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BU of 3w7x by Molmil
Crystal structure of E. coli YgjK D324N complexed with melibiose
Descriptor: CALCIUM ION, Uncharacterized protein YgjK, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose
Authors:Miyazaki, T, Ichikawa, M, Yokoi, G, Kitaoka, M, Mori, H, Kitano, Y, Nishikawa, A, Tonozuka, T.
Deposit date:2013-03-08
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a bacterial glycoside hydrolase family 63 enzyme in complex with its glycosynthase product, and insights into the substrate specificity.
Febs J., 280, 2013
3VSS
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BU of 3vss by Molmil
Microbacterium saccharophilum K-1 beta-fructofuranosidase catalytic domain complexed with fructose
Descriptor: Beta-fructofuranosidase, beta-D-fructofuranose
Authors:Tonozuka, T, Tamaki, A, Yokoi, G, Miyazaki, T, Ichikawa, M, Nishikawa, A, Ohta, Y, Hidaka, Y, Katayama, K, Hatada, Y, Ito, T, Fujita, K.
Deposit date:2012-05-08
Release date:2012-08-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of a lactosucrose-producing enzyme, Arthrobacter sp. K-1 beta-fructofuranosidase
Enzyme.Microb.Technol., 51, 2012
3VSR
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BU of 3vsr by Molmil
Microbacterium saccharophilum K-1 beta-fructofuranosidase catalytic domain
Descriptor: Beta-fructofuranosidase
Authors:Tonozuka, T, Tamaki, A, Yokoi, G, Miyazaki, T, Ichikawa, M, Nishikawa, A, Ohta, Y, Hidaka, Y, Katayama, K, Hatada, Y, Ito, T, Fujita, K.
Deposit date:2012-05-08
Release date:2012-08-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a lactosucrose-producing enzyme, Arthrobacter sp. K-1 beta-fructofuranosidase
Enzyme.Microb.Technol., 51, 2012

 

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