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6B5V
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BU of 6b5v by Molmil
Structure of TRPV5 in complex with econazole
Descriptor: 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y.
Deposit date:2017-09-29
Release date:2017-12-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
6DMR
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BU of 6dmr by Molmil
Lipid-bound full-length rbTRPV5
Descriptor: Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DMU
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BU of 6dmu by Molmil
PI(4,5)P2 bound full-length rbTRPV5
Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6DMW
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BU of 6dmw by Molmil
Calmodulin-bound full-length rbTRPV5
Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y.
Deposit date:2018-06-05
Release date:2018-10-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
6PBF
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BU of 6pbf by Molmil
ZINC9155420-bound TRPV5 in nanodiscs
Descriptor: (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2019-06-13
Release date:2019-11-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019
6PBE
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BU of 6pbe by Molmil
ZINC17988990-bound TRPV5 in nanodiscs
Descriptor: (4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methyl 3-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propanoate, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y.
Deposit date:2019-06-13
Release date:2019-11-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure-based characterization of novel TRPV5 inhibitors.
Elife, 8, 2019

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