Author results

1BRF
  • Download 1brf
  • View 1brf
Molmil generated image of 1brf
RUBREDOXIN (WILD TYPE) FROM PYROCOCCUS FURIOSUS
Descriptor:PROTEIN (RUBREDOXIN), FE (III) ION
Authors:Bau, R., Rees, D.C., Kurtz, D.M., Scott, R.A., Huang, H., Adams, M.W.W., Eidsness, M.K.
Deposit date:1998-08-24
Release date:1998-09-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Crystal Structure of Rubredoxin from Pyrococcus Furiosus at 0.95 Angstroms Resolution, and the structures of N-terminal methionine and formylmethionine variants of Pf Rd. Contributions of N-terminal interactions to thermostability
J.BIOL.INORG.CHEM., 3, 1998
5TNV
  • Download 5tnv
  • View 5tnv
Molmil generated image of 5tnv
CRYSTAL STRUCTURE OF A XYLOSE ISOMERASE-LIKE TIM BARREL PROTEIN FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH MAGNESIUM
Descriptor:AP endonuclease, family protein 2, MAGNESIUM ION
Authors:Cook, W.J., Fedorov, A.A., Fedorov, E.V., Huang, H., Bonanno, J.B., Gerlt, J.A., Almo, S.C.
Deposit date:2016-10-14
Release date:2016-11-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Crystal Structure of a Xylose isomerase-like TIM barrel Protein from Mycobacterium smegmatis in Complex with Magnesium
To Be Published
1BQ8
  • Download 1bq8
  • View 1bq8
Molmil generated image of 1bq8
RUBREDOXIN (METHIONINE MUTANT) FROM PYROCOCCUS FURIOSUS
Descriptor:PROTEIN (RUBREDOXIN), FE (III) ION
Authors:Bau, R., Rees, D.C., Kurtz, D.M., Scott, R.A., Huang, H., Adams, M.W.W., Eidsness, M.K.
Deposit date:1998-08-22
Release date:1998-08-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal Structure of Rubredoxin from Pyrococcus Furiosus at 0.95 Angstroms Resolution, and the structures of N-terminal methionine and formylmethionine variants of Pf Rd. Contributions of N-terminal interactions to thermostability
J.BIOL.INORG.CHEM., 3, 1998
4CQH
  • Download 4cqh
  • View 4cqh
Molmil generated image of 4cqh
STRUCTURE OF INFRARED FLUORESCENT PROTEIN IFP2.0
Descriptor:BACTERIOPHYTOCHROME, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, SODIUM ION
Authors:Lafaye, C., Yu, D., Noirclerc-Savoye, M., Shu, X., Royant, A.
Deposit date:2014-02-17
Release date:2014-05-28
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:An Improved Monomeric Infrared Fluorescent Protein for Neuronal and Tumour Brain Imaging.
Nat.Commun., 5, 2014
5SZC
  • Download 5szc
  • View 5szc
Molmil generated image of 5szc
STRUCTURE OF HUMAN DPF3 DOUBLE-PHD DOMAIN BOUND TO HISTONE H3 TAIL PEPTIDE WITH MONOMETHYLATED K4 AND ACETYLATED K14
Descriptor:Zinc finger protein DPF3, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N., Local, A., Shiau, A., Ren, B., Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.193 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
1BQ9
  • Download 1bq9
  • View 1bq9
Molmil generated image of 1bq9
RUBREDOXIN (FORMYL METHIONINE MUTANT) FROM PYROCOCCUS FURIOSUS
Descriptor:PROTEIN (RUBREDOXIN), FE (III) ION
Authors:Bau, R., Rees, D.C., Kurtz, D.M., Scott, R.A., Huang, H., Adams, M.W.W., Eidsness, M.K.
Deposit date:1998-08-22
Release date:1998-08-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structure of Rubredoxin from Pyrococcus Furiosus at 0.95 Angstroms Resolution, and the structures of N-terminal methionine and formylmethionine variants of Pf Rd. Contributions of N-terminal interactions to thermostability
J.BIOL.INORG.CHEM., 3, 1998
5SZB
  • Download 5szb
  • View 5szb
Molmil generated image of 5szb
STRUCTURE OF HUMAN DPF3 DOUBLE-PHD DOMAIN BOUND TO HISTONE H3 TAIL PEPTIDE WITH ACETYLATED K14
Descriptor:Zinc finger protein DPF3, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N., Local, A., Shiau, A., Ren, B., Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
6KBX
  • Download 6kbx
  • View 6kbx
Molmil generated image of 6kbx
CRYSTAL STRUCTURE OF YEDK IN COMPLEX WITH SSDNA CONTAINING ABASIC SITE
Descriptor:SOS response-associated protein, DNA 5'-D (*CP*GP*GP*TP* (PED)P*GP*AP*TP*TP*C)-3'
Authors:Wang, N., Bao, H., Huang, H.
Deposit date:2019-06-26
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.221 Å)
Cite:Crystal structure of yedK in complex with ssDNA containing abasic site
To Be Published
3QU5
  • Download 3qu5
  • View 3qu5
Molmil generated image of 3qu5
CRYSTAL STRUCTURE OF PYROPHOSPHATASE FROM BACTEROIDES THETAIOTAOMICRON, ASP11ASN MUTANT
Descriptor:INORGANIC PYROPHOSPHATASE, CHLORIDE ION
Authors:Patskovsky, Y., Huang, H., Toro, R., Gerlt, J.A., Burley, S.K., Dunaway-Mariano, D., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC), Enzyme Function Initiative (EFI)
Deposit date:2011-02-23
Release date:2011-04-27
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase.
Biochemistry, 50, 2011
3QXG
  • Download 3qxg
  • View 3qxg
Molmil generated image of 3qxg
CRYSTAL STRUCTURE OF PYROPHOSPHATASE FROM BACTEROIDES THETAIOTAOMICRON COMPLEXED WITH CALCIUM, A CLOSED CAP CONFORMATION
Descriptor:INORGANIC PYROPHOSPHATASE, ACETATE ION, CALCIUM ION, ...
Authors:Patskovsky, Y., Huang, H., Toro, R., Gerlt, J.A., Burley, S.K., Dunaway-Mariano, D., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC), Enzyme Function Initiative (EFI)
Deposit date:2011-03-01
Release date:2011-04-27
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase.
Biochemistry, 50, 2011
5VEI
  • Download 5vei
  • View 5vei
Molmil generated image of 5vei
CRYSTAL STRUCTURE OF THE SH3 DOMAIN OF HUMAN SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 2
Descriptor:Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y., Tempel, W., Huang, H., Gu, J., Liu, K., Sidhu, S.S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
4RS3
  • Download 4rs3
  • View 4rs3
Molmil generated image of 4rs3
CRYSTAL STRUCTURE OF CARBOHYDRATE TRANSPORTER A0QYB3 FROM MYCOBACTERIUM SMEGMATIS STR. MC2 155, TARGET EFI-510969, IN COMPLEX WITH XYLITOL
Descriptor:ABC transporter, carbohydrate uptake transporter-2 (CUT2) family, periplasmic sugar-binding protein, ...
Authors:Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Morisco, L.L., Wasserman, S.R., Chamala, S., Attonito, J.D., Scott Glenn, A., Chowdhury, S., Lafleur, J., Hillerich, B., Siedel, R.D., Love, J., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
Deposit date:2014-11-06
Release date:2014-11-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
J.Am.Chem.Soc., 137, 2015
6EDF
  • Download 6edf
  • View 6edf
Molmil generated image of 6edf
FRAGMENT OF A TYROSINE-PROTEIN KINASE
Descriptor:FYN, GLYCEROL, UNKNOWN ATOM OR ION
Authors:Tempel, W., Huang, H., Sochirca, I., Liu, K., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Sidhu, S.S., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2018-08-09
Release date:2018-08-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Fragment of a tyrosine-protein kinase
To be Published
3QUT
  • Download 3qut
  • View 3qut
Molmil generated image of 3qut
CRYSTAL STRUCTURE OF PYROPHOSPHATASE FROM BACTEROIDES THETAIOTAOMICRON, ASP13ASN MUTANT, AN OPEN CAP CONFORMATION
Descriptor:INORGANIC PYROPHOSPHATASE, MAGNESIUM ION, D-MALATE, ...
Authors:Patskovsky, Y., Huang, H., Toro, R., Gerlt, J.A., Burley, S.K., Dunaway-Mariano, D., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC), Enzyme Function Initiative (EFI)
Deposit date:2011-02-24
Release date:2011-04-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase.
Biochemistry, 50, 2011
4D3T
  • Download 4d3t
  • View 4d3t
Molmil generated image of 4d3t
STRUCTURE OF BACILLUS SUBTILIS NITRIC OXIDE SYNTHASE IN COMPLEX WITH N-{3-[(1S)-2-(3-{(Z)-[AMINO(THIOPHEN-2-YL)METHYLIDENE]AMINO}PHENOXY)-1-HYDROXYETHYL]PHENYL}THIOPHENE-2-CARBOXIMIDAMIDE
Descriptor:NITRIC OXIDE SYNTHASE OXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION, ...
Authors:Holden, J.K., Poulos, T.L.
Deposit date:2014-10-23
Release date:2015-01-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors.
J.Med.Chem., 58, 2015
4F5B
  • Download 4f5b
  • View 4f5b
Molmil generated image of 4f5b
TRIPLE MUTANT SRC SH2 DOMAIN BOUND TO PHOSPHOTYROSINE
Descriptor:Proto-oncogene tyrosine-protein kinase Src, O-PHOSPHOTYROSINE
Authors:Kaneko, T., Huang, H., Cao, X., Li, C., Voss, C., Sidhu, S.S., Li, S.S.
Deposit date:2012-05-12
Release date:2012-10-03
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Superbinder SH2 Domains Act as Antagonists of Cell Signaling.
Sci.Signal., 5, 2012
6DRR
  • Download 6drr
  • View 6drr
Molmil generated image of 6drr
CRYSTAL STRUCTURE OF CJ0485 DEHYDROGENASE
Descriptor:Short-chain dehydrogenase, 1,2-ETHANEDIOL
Authors:Pluvinage, B., Boraston, A.B.
Deposit date:2018-06-12
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:No longer asaccharolytic - L-fucose and D-arabinose metabolism in Campylobacter jejuni
To be published
6J4P
  • Download 6j4p
  • View 6j4p
Molmil generated image of 6j4p
STRUCTURAL BASIS OF TUBULIN DETYROSINATION BY VASOHIBINS-SVBP ENZYME COMPLEX AND FUNCTIONAL IMPLICATIONS
Descriptor:Tubulinyl-Tyr carboxypeptidase 2, Small vasohibin-binding protein, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine
Authors:Wang, N., Bao, H., Huang, H.
Deposit date:2019-01-10
Release date:2019-05-01
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications
To Be Published
3QYP
  • Download 3qyp
  • View 3qyp
Molmil generated image of 3qyp
CRYSTAL STRUCTURE OF PYROPHOSPHATASE FROM BACTEROIDES THETAIOTAOMICRON, GLU47ASN MUTANT COMPLEXED WITH CALCIUM AND PHOSPHATE
Descriptor:INORGANIC PYROPHOSPHATASE, PHOSPHATE ION, CALCIUM ION, ...
Authors:Patskovsky, Y., Huang, H., Toro, R., Gerlt, J.A., Burley, S.K., Dunaway-Mariano, D., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC), Enzyme Function Initiative (EFI)
Deposit date:2011-03-03
Release date:2011-04-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily: Bacteroides thetaiotaomicron BT2127 Is an Inorganic Pyrophosphatase.
Biochemistry, 50, 2011
4KSJ
  • Download 4ksj
  • View 4ksj
Molmil generated image of 4ksj
CRYSTAL STRUCTURE OF THE OTU DOMAIN OF GUMBY/FAM105B AT 1.6 ANGSTROM
Descriptor:Protein FAM105B, BETA-MERCAPTOETHANOL, GLYCEROL
Authors:Ceccarelli, D.F., Juang, Y.-C., Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4RSM
  • Download 4rsm
  • View 4rsm
Molmil generated image of 4rsm
CRYSTAL STRUCTURE OF CARBOHYDRATE TRANSPORTER MSMEG_3599 FROM MYCOBACTERIUM SMEGMATIS STR. MC2 155, TARGET EFI-510970, IN COMPLEX WITH D-THREITOL
Descriptor:Periplasmic binding protein/LacI transcriptional regulator, D-Threitol
Authors:Patskovsky, Y., Toro, R., Bhosle, R., Al Obaidi, N., Morisco, L.L., Wasserman, S.R., Chamala, S., Attonito, J.D., Scott Glenn, A., Chowdhury, S., Lafleur, J., Hillerich, B., Siedel, R.D., Love, J., Whalen, K.L., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
Deposit date:2014-11-08
Release date:2014-12-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
J.Am.Chem.Soc., 137, 2015
6C52
  • Download 6c52
  • View 6c52
Molmil generated image of 6c52
CROSS-ALPHA AMYLOID-LIKE STRUCTURE ALPHATET
Descriptor:Cross-alpha Amyloid-like Structure alphaTet, GLYCEROL
Authors:Liu, L., Zhang, S.Q.
Deposit date:2018-01-13
Release date:2018-08-15
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
6KBS
  • Download 6kbs
  • View 6kbs
Molmil generated image of 6kbs
CRYSTAL STRUCTURE OF YEDK IN COMPLEX WITH SSDNA
Descriptor:SOS response-associated protein, DNA (5'-D(*CP*GP*GP*TP*CP*GP*AP*TP*TP*C)-3')
Authors:Wang, N., Bao, H., Huang, H.
Deposit date:2019-06-26
Release date:2019-07-10
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structure of yedK in complex with ssDNA
To Be Published
6J7B
  • Download 6j7b
  • View 6j7b
Molmil generated image of 6j7b
CRYSTAL STRUCTURE OF VASH1-SVBP IN COMPLEX WITH EPOY
Descriptor:Tubulinyl-Tyr carboxypeptidase 1, Small vasohibin-binding protein, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine
Authors:Wang, N., Bao, H., Huang, H., Wu, B.
Deposit date:2019-01-17
Release date:2019-06-19
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.618 Å)
Cite:Molecular basis of vasohibins-mediated detyrosination and its impact on spindle function and mitosis.
Cell Res., 29, 2019
4UGK
  • Download 4ugk
  • View 4ugk
Molmil generated image of 4ugk
STRUCTURE OF BACILLUS SUBTILIS NITRIC OXIDE SYNTHASE IN COMPLEX WITH 6-(2-(5-(2-(DIMETHYLAMINO)ETHYL)PYRIDIN-3-YL)ETHYL)-4-METHYLPYRIDIN-2- AMINE
Descriptor:NITRIC OXIDE SYNTHASE OXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ...
Authors:Holden, J.K., Poulos, T.L.
Deposit date:2015-03-22
Release date:2015-06-24
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.
Biochemistry, 54, 2015