Author results

1IK1
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SOLUTION STRUCTURE OF AN RNA HAIRPIN FROM HRV-14
Descriptor:5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3'
Authors:Huang, H., Alexandrov, A., Chen, X., Barnes III, T.W., Zhang, H., Dutta, K., Pascal, S.M.
Deposit date:2001-05-01
Release date:2001-07-18
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:Structure of an RNA hairpin from HRV-14.
Biochemistry, 40, 2001
2K8T
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SOLUTION NMR STRUCTURE OF TRANS-4-HYDROXYNONENAL DERIVED DG ADDUCT OF (6R,8S,11R)-CONFIGURATION OPPOSITE DC
Descriptor:5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3', (2S,5R)-5-pentyltetrahydrofuran-2-ol
Authors:Huang, H., Wang, H., Qi, N., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2008-09-23
Release date:2008-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
Biochemistry, 47, 2008
2K8U
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SOLUTION NMR STRUCTURE OF TRANS-4-HYDROXYNONENAL DERIVED DG ADDUCT OF (6S,8R,11S)-CONFIGURATION MATCHED WITH DC
Descriptor:5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3', (2S,5R)-5-pentyltetrahydrofuran-2-ol
Authors:Huang, H., Wang, H., Qi, N., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2008-09-23
Release date:2008-11-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
Biochemistry, 47, 2008
2KAR
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HNE-DG ADDUCT MISMATCHED WITH DA IN ACIDIC SOLUTION
Descriptor:5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3', (4S)-nonane-1,4-diol
Authors:Huang, H., Wang, H., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2008-11-13
Release date:2009-05-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA
Chem.Res.Toxicol., 22, 2009
2KAS
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HNE-DG ADDUCT MISMATCHED WITH DA IN BASIC SOLUTION
Descriptor:5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DAP*DGP*DCP*DTP*DAP*DGP*DC)-3', (4S)-nonane-1,4-diol
Authors:Huang, H., Wang, H., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2008-11-13
Release date:2009-05-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA
Chem.Res.Toxicol., 22, 2009
2KEB
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NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE DNA POLYMERASE ALPHA P68 SUBUNIT
Descriptor:DNA polymerase subunit alpha B
Authors:Huang, H., Weiner, B.E., Zhang, H., Fuller, B.E., Gao, Y., Wile, B.M., Chazin, W.J., Fanning, E.
Deposit date:2009-01-28
Release date:2010-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome.
J.Biol.Chem., 285, 2010
2KSZ
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THE SOLUTION STRUCTURE OF THE MAGNESIUM BOUND SOYBEAN CALMODULIN ISOFORM 4 N-DOMAIN
Descriptor:Putative uncharacterized protein, MAGNESIUM ION
Authors:Huang, H., Ishida, H., Vogel, H.J.
Deposit date:2010-01-14
Release date:2010-03-09
Last modified:2014-12-10
Method:SOLUTION NMR
Cite:The solution structure of the Mg2+ form of soybean calmodulin isoform 4 reveals unique features of plant calmodulins in resting cells.
Protein Sci., 19, 2010
2LBI
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N2-DG:N2-DG INTERSTRAND CROSS-LINK INDUCED BY TRANS-4-HYDROXYNONENAL
Descriptor:DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3'), (4S)-nonane-1,4-diol
Authors:Huang, H., Kozekov, I.D., Wang, H., Kozekova, A., Rizzo, C.J., Stone, M.P.
Deposit date:2011-03-31
Release date:2012-04-04
Method:SOLUTION NMR
Cite:Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct.
J.Am.Chem.Soc., 133, 2011
2LG2
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STRUCTURE OF THE DUPLEX CONTAINING HNE DERIVED (6S,8R,11S) N2-DG CYCLIC HEMIACETAL WHEN PLACED OPPOSITE DT
Descriptor:DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*TP*GP*CP*TP*AP*GP*C)-3'), (2R,5S)-5-pentyltetrahydrofuran-2-ol
Authors:Huang, H., Wang, H., Kozekova, A., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2011-07-19
Release date:2012-08-01
Method:SOLUTION NMR
Cite:Ring-chain tautomerization of trans-4-hydroxynonenal derived (6S,8R,11S) gamma-hydroxy-1,N2-propano-deoxyguanosine adduct when placed opposite 2'-deoxythymidine in duplex
To be Published
2LG3
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STRUCTURE OF THE DUPLEX CONTAINING HNE DERIVED (6S,8R,11S) GAMMA-HO-PDG WHEN PLACED OPPOSITE DT
Descriptor:DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*TP*GP*CP*TP*AP*GP*C)-3'), (4S)-nonane-1,4-diol
Authors:Huang, H., Wang, H., Kozekova, A., Lloyd, R.S., Rizzo, C.J., Stone, M.P.
Deposit date:2011-07-19
Release date:2012-08-01
Method:SOLUTION NMR
Cite:Ring-chain tautomerization of trans-4-hydroxynonenal derived (6S,8R,11S) gamma-hydroxy-1,N2-propano-deoxyguanosine adduct when placed opposite 2'-deoxythymidine in duplex
To be Published
2L4H
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THE SOLUTION STRUCTURE OF CALCIUM BOUND CIB1
Descriptor:Calcium and integrin-binding protein 1, CALCIUM ION
Authors:Huang, H., Vogel, H.J.
Deposit date:2010-10-06
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structures of Ca2+-CIB1 and Mg2+-CIB1 and Their Interactions with the Platelet Integrin {alpha}IIb Cytoplasmic Domain.
J.Biol.Chem., 286, 2011
2L4I
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THE SOLUTION STRUCTURE OF MAGNESIUM BOUND CIB1
Descriptor:Calcium and integrin-binding protein 1, MAGNESIUM ION
Authors:Huang, H., Vogel, H.J.
Deposit date:2010-10-06
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structures of Ca2+-CIB1 and Mg2+-CIB1 and Their Interactions with the Platelet Integrin {alpha}IIb Cytoplasmic Domain.
J.Biol.Chem., 286, 2011
3CQ0
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CRYSTAL STRUCTURE OF TAL2_YEAST
Descriptor:Putative transaldolase YGR043C, 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, ...
Authors:Huang, H., Niu, L., Teng, M.
Deposit date:2008-04-01
Release date:2009-04-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae
Proteins, 73, 2008
2G4A
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SOLUTION STRUCTURE OF A BROMODOMAIN FROM RING3 PROTEIN
Descriptor:Bromodomain-containing protein 2
Authors:Huang, H., Wu, J., Shi, Y.
Deposit date:2006-02-21
Release date:2007-02-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a Bromodomain from RING3
to be published
2JAZ
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CRYSTAL STRUCTURE OF THE MUTANT N560D OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
Descriptor:COLICIN E7 IMMUNITY PROTEIN, COLICIN E7, ZINC ION, ...
Authors:Huang, H., Yuan, H.S.
Deposit date:2006-12-01
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
2JB0
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CRYSTAL STRUCTURE OF THE MUTANT H573A OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
Descriptor:COLICIN E7 IMMUNITY PROTEIN, COLICIN E7, ZINC ION
Authors:Huang, H., Yuan, H.S.
Deposit date:2006-12-01
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
2JBG
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CRYSTAL STRUCTURE OF THE MUTANT N560A OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
Descriptor:COLICIN-E7 IMMUNITY PROTEIN, COLICIN E7, ZINC ION, ...
Authors:Huang, H., Yuan, H.S.
Deposit date:2006-12-07
Release date:2007-04-03
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
2KNK
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STRUCTURE OF THE TRIMETHYLENE N2-DG:N2-DG INTERSTRAND CROSS-LINK IN 5'-CPG-3' SEQUENCE CONTEXT
Descriptor:DNA (5'-D(*AP*GP*GP*CP*GP*CP*CP*T)-3'), PROPANE
Authors:Huang, H., Dooley, P.A., Harris, C.M., Harris, T.M., Stone, M.P.
Deposit date:2009-08-26
Release date:2009-09-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.
Chem.Res.Toxicol., 22, 2009
2KNL
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STRUCTURE OF THE TRIMETHYLENE N2-DG:N2-DG INTERSTRAND CROSS-LINK IN THE 5'-GPC-3' SEQUENCE CONTEXT
Descriptor:DNA (5'-D(*TP*CP*CP*GP*CP*GP*GP*A)-3'), PROPANE
Authors:Huang, H., Dooley, P.A., Harris, C.M., Harris, T.M., Stone, M.P.
Deposit date:2009-08-26
Release date:2009-09-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.
Chem.Res.Toxicol., 22, 2009
2KV6
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TETRAPEPTIDE KWKK CONJUGATED TO OLIGONUCLEOTIDE DUPLEX BY A TRIMETHYLENE TETHER
Descriptor:5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide
Authors:Huang, H., Kozekov, I.D., Kozekova, A., Rizzo, C.J., McCullough, A., LLoyd, R.S., Stone, M.P.
Deposit date:2010-03-08
Release date:2010-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage .
Biochemistry, 49, 2010
2LFA
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OLIGONUCLEOTIDE DUPLEX CONTANING (5'S)-8,5'-CYCLO-2'-DEOXYGUANSINE
Descriptor:DNA (5'-D(*GP*TP*GP*CP*(2LF)P*TP*GP*TP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*AP*CP*AP*CP*GP*CP*AP*C)-3')
Authors:Huang, H., Das, R.S., Basu, A., Stone, M.P.
Deposit date:2011-06-29
Release date:2012-01-04
Method:SOLUTION NMR
Cite:Structure of (5'S)-8,5'-Cyclo-2'-deoxyguanosine in DNA.
J.Am.Chem.Soc., 133, 2011
2LFX
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STRUCTURE OF THE DUPLEX WHEN (5'S)-8,5'-CYCLO-2'-DEOXYGUANOSINE IS PLACED OPPOSITE DT
Descriptor:DNA (5'-D(*GP*TP*GP*CP*(2LF)P*TP*GP*TP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*AP*CP*AP*TP*GP*CP*AP*C)-3')
Authors:Huang, H., Das, R.S., Basu, A., Stone, M.P.
Deposit date:2011-07-18
Release date:2012-06-27
Method:SOLUTION NMR
Cite:Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT.
Chem.Res.Toxicol., 25, 2012
2LFY
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STRUCTURE OF THE DUPLEX WHEN (5'S)-8,5'-CYCLO-2'-DEOXYGUANOSINE IS PLACED OPPOSITE DA
Descriptor:DNA (5'-D(*GP*TP*GP*CP*(2LF)P*TP*GP*TP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*AP*CP*AP*AP*GP*CP*AP*C)-3')
Authors:Huang, H., Das, R.S., Basu, A., Stone, M.P.
Deposit date:2011-07-18
Release date:2012-06-27
Method:SOLUTION NMR
Cite:Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT.
Chem.Res.Toxicol., 25, 2012
2LG0
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STRUCTURE OF THE DUPLEX CONTAINING (5'S)-8,5'-CYCLO-2'-DEOXYADENOSINE
Descriptor:DNA (5'-D(*GP*TP*GP*CP*(02I)P*TP*GP*TP*TP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*AP*AP*CP*AP*TP*GP*CP*AP*C)-3')
Authors:Huang, H., Das, R.S., Basu, A., Stone, M.P.
Deposit date:2011-07-18
Release date:2012-06-27
Method:SOLUTION NMR
Cite:Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA.
J.Am.Chem.Soc., 133, 2011
2LM5
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SOLUTION STRUCTURE OF CA2+-CIB1 IN COMPLEX WITH THE CYTOPLASMIC DOMAIN OF THE INTEGRIN AIIB SUBUNIT
Descriptor:Calcium and integrin-binding protein 1, CALCIUM ION
Authors:Huang, H., Vogel, H.J.
Deposit date:2011-11-22
Release date:2012-02-15
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Structural basis for the activation of platelet integrin alphaIIb-beta3 by calcium- and integrin-binding protein 1.
J.Am.Chem.Soc., 134, 2012