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1BFS
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BU of 1bfs by Molmil
STRUCTURE OF NF-KB P50 HOMODIMER BOUND TO A KB SITE
Descriptor: NUCLEAR FACTOR NF-KAPPA-B P50
Authors:Huang, D.B, Huxford, T, Chen, Y.Q, Ghosh, G.
Deposit date:1997-09-12
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits.
Structure, 5, 1997
1BFT
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BU of 1bft by Molmil
STRUCTURE OF NF-KB P50 HOMODIMER BOUND TO A KB SITE
Descriptor: NUCLEAR FACTOR NF-KAPPA-B P65
Authors:Huang, D.B, Huxford, T, Chen, Y.Q, Ghosh, G.
Deposit date:1997-09-12
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits.
Structure, 5, 1997
1SGS
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BU of 1sgs by Molmil
Crystal structure of a free kB DNA
Descriptor: CALCIUM ION, kB DNA
Authors:Huang, D.B, Phelps, C.B, Fusco, A.J, Ghosh, G.
Deposit date:2004-02-24
Release date:2004-03-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB.
J.Mol.Biol., 346, 2005
1GJI
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BU of 1gji by Molmil
Crystal structure of c-Rel bound to DNA
Descriptor: C-REL PROTO-ONCOGENE PROTEIN, IL-2 CD28RE DNA
Authors:Huang, D.B, Chen, Y.Q, Ruetsche, M, Phelps, C.B, Ghosh, G.
Deposit date:2001-05-30
Release date:2002-05-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2.
Structure, 9, 2001
1WTL
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BU of 1wtl by Molmil
COMPARISON OF CRYSTAL STRUCTURES OF TWO HOMOLOGOUS PROTEINS: STRUCTURAL ORIGIN OF ALTERED DOMAIN INTERACTIONS IN IMMUNOGLOBULIN LIGHT CHAIN DIMERS
Descriptor: BENCE-JONES PROTEIN MCG (LIGHT CHAIN)
Authors:Huang, D.B, Chang, C.H, Schiffer, M.
Deposit date:1994-06-08
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Comparison of crystal structures of two homologous proteins: structural origin of altered domain interactions in immunoglobulin light-chain dimers.
Biochemistry, 33, 1994
1ZKA
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BU of 1zka by Molmil
NF-kB RelB forms an intertwined homodimer, Y300S mutant
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2005-05-02
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:NF-kappaB RelB forms an intertwined homodimer.
Structure, 13, 2005
1ZK9
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BU of 1zk9 by Molmil
NF-kB RelB forms an intertwined homodimer
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2005-05-02
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:NF-kappaB RelB Forms an Intertwined Homodimer.
Structure, 13, 2005
1OOA
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BU of 1ooa by Molmil
CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER
Descriptor: Nuclear factor NF-kappa-B p105 subunit, RNA aptamer
Authors:Huang, D.B, Vu, D, Cassiday, L.A, Zimmerman, J.M, Maher III, L.J, Ghosh, G.
Deposit date:2003-03-03
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
Proc.Natl.Acad.Sci.USA, 100, 2003
4JHB
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BU of 4jhb by Molmil
Crystal structure of RelB double mutants: Y300F/I335F
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2013-03-04
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of RelB double mutants: Y300F/I335F
TO BE PUBLISHED
1BJM
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BU of 1bjm by Molmil
LOC NAKS, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN NAKSO4
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
3BJL
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BU of 3bjl by Molmil
LOC, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN AMMONIUM SULFATE
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
4BJL
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BU of 4bjl by Molmil
LOCW, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN DISTILLED WATER
Descriptor: LOC - LAMBDA 1 TYPE LIGHT-CHAIN DIMER
Authors:Schiffer, M, Huang, D.B.
Deposit date:1995-05-26
Release date:1995-12-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three quaternary structures for a single protein.
Proc.Natl.Acad.Sci.USA, 93, 1996
1LIL
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BU of 1lil by Molmil
BENCE JONES PROTEIN CLE, A LAMBDA III IMMUNOGLOBULIN LIGHT-CHAIN DIMER
Descriptor: LAMBDA III BENCE JONES PROTEIN CLE
Authors:Schiffer, M, Huang, D.B.
Deposit date:1996-05-13
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Pitfalls of molecular replacement: the structure determination of an immunoglobulin light-chain dimer.
Acta Crystallogr.,Sect.D, 52, 1996
4JGM
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BU of 4jgm by Molmil
Crystal structure of RelB double mutants: Y300F/I335V
Descriptor: Transcription factor RelB
Authors:Huang, D.B, Vu, D, Ghosh, G.
Deposit date:2013-03-01
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
2V2T
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BU of 2v2t by Molmil
X-ray structure of a NF-kB p50-RelB-DNA complex
Descriptor: 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB
Authors:Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G.
Deposit date:2007-06-07
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites.
J.Mol.Biol., 373, 2007
1VKX
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BU of 1vkx by Molmil
CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
Descriptor: DNA (5'-D(*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*C)-3'), PROTEIN (NF-KAPPA B P50 SUBUNIT), ...
Authors:Chen, F, Huang, D.B, Ghosh, G.
Deposit date:1997-09-17
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Nature, 391, 1998
3DO7
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BU of 3do7 by Molmil
X-ray structure of a NF-kB p52/RelB/DNA complex
Descriptor: 5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3', Avian reticuloendotheliosis viral (V-rel) oncogene related B, Nuclear factor NF-kappa-B p100 subunit
Authors:Fusco, A, Huang, D.B, Miller, D, Vu, D, Ghosh, G.
Deposit date:2008-07-03
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA
TO BE PUBLISHED
4E3C
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BU of 4e3c by Molmil
X-ray crystal structure of human IKK2 in an active conformation
Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta
Authors:Polley, S, Huang, D.B, Hauenstein, A.V, Ghosh, G, Huxford, T.
Deposit date:2012-03-09
Release date:2013-06-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.98 Å)
Cite:X-ray crystal structure of human IKK2 in an active conformation
Plos.Biol., 2013
3JV0
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BU of 3jv0 by Molmil
Crystal structure of a mutant of RelB dimerization domain(M6)
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Instability of the RelB dimerization domain is functionally importent
To be Published
3JV5
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BU of 3jv5 by Molmil
Crystal structure of the dimerization domains p52 homodimer
Descriptor: Nuclear factor NF-kappa-B p100 subunit
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Instability of the RelB dimerization domain is functionally important
To be Published
3JSS
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BU of 3jss by Molmil
Crystal structure of a mutant RelB dimerization domain
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-10
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
3JUZ
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BU of 3juz by Molmil
Crystal structure of a mutant of RelB dimerization domain(M5)
Descriptor: Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Instability of the RelB dimerization domain is functionally important
To be Published
3JV6
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BU of 3jv6 by Molmil
Crystal structure of the dimerization domains p52 and RelB
Descriptor: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION, Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
3JV4
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BU of 3jv4 by Molmil
Crystal structure of the dimerization domains p50 and RelB
Descriptor: Nuclear factor NF-kappa-B p105 subunit, Transcription factor RelB
Authors:Vu, D, Huang, D.B, Ghosh, G.
Deposit date:2009-09-15
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
4OT9
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BU of 4ot9 by Molmil
crystal structure of the C-terminal domain of p100/NF-kB2
Descriptor: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION
Authors:Tao, Z.H, Huang, D.B, Fusco, A, Gupta, K, Ware, C.F, Duynne, G.V.
Deposit date:2014-02-13
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation.
Proc.Natl.Acad.Sci.USA, 111, 2014

 

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