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6BKD
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3D
Descriptor:Polyprotein, Fab AR3D heavy chain, Fab AR3D light chain, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019
6BKC
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3B
Descriptor:Fab AR3B heavy chain, Fab AR3B light chain, Polyprotein, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019
6BKB
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3A
Descriptor:Fab AR3A heavy chain, Polyprotein, Fab AR3A light chain, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019
5ZOG
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CRYSTAL STRUCTURE OF R192F HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*TP*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOF
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CRYSTAL STRUCTURE OF D181A/R192F HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOE
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CRYSTAL STRUCTURE OF D181A HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOD
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CRYSTAL STRUCTURE OF HFEN1 IN APO FORM
Descriptor:Flap endonuclease 1, MAGNESIUM ION, POTASSIUM ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5W6D
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CRYSTAL STRUCTURE OF BG505-SOSIP.V4.1-GT1-N137A IN COMPLEX WITH FABS 35022 AND 9H/109L
Descriptor:BG505-SOSIP.v4.1-GT1-N137A gp120, BG505-SOSIP.v4.1-GT1-N137A gp41, 109L FAB light chain, ...
Authors:Garces, F., Stanfield, R.L., Wilson, I.A.
Deposit date:2017-06-16
Release date:2017-07-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.
J. Exp. Med., 214, 2017
5JDK
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CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF SAP1 IN FISSION YEAST S.POMBE
Descriptor:Switch-activating protein 1, GLYCEROL
Authors:He, P., Wang, T.
Deposit date:2016-04-17
Release date:2017-02-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (0.998 Å)
Cite:Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe.
J. Biol. Chem., 292, 2017
5H7F
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CRYSTAL STRUCTURE OF MN-DERIVATIVE DRCPDASE
Descriptor:RNA 2',3'-cyclic phosphodiesterase, SULFATE ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2016-11-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal Structure of Mn-derivative drCPDase
To be published
5H7E
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CRYSTAL STRUCTURE OF NATIVE DRCPDASE
Descriptor:RNA 2',3'-cyclic phosphodiesterase, GLYCEROL, SULFATE ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2016-11-18
Release date:2017-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the RNA 2',3'-cyclic phosphodiesterase from Deinococcus radiodurans
Acta Crystallogr F Struct Biol Commun, 73, 2017
5FJS
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BACTERIAL BETA-GLUCOSIDASE REVEALS THE STRUCTURAL AND FUNCTIONAL BASIS OF GENETIC DEFECTS IN HUMAN GLUCOCEREBROSIDASE 2 (GBA2)
Descriptor:GLUCOSYLCERAMIDASE, CALCIUM ION
Authors:Charoenwattanasatien, R., Pengthaisong, S., Breen, I., Mutoha, R., Sansenya, S., Hua, Y., Tankrathok, A., Wu, L., Songsiriritthigul, C., Tanaka, H., Williams, S.J., Davies, G.J., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-10-12
Release date:2016-05-11
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bacterial Beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (Gba2)
Acs Chem.Biol., 11, 2016
5F56
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STRUCTURE OF RECJ COMPLEXED WITH DNA AND SSB-CT
Descriptor:Single-stranded-DNA-specific exonuclease, DNA (5'-D(*CP*TP*GP*AP*TP*GP*GP*CP*A)-3'), ALA-ASP-LEU-PRO-PHE, ...
Authors:Zhao, Y., Hua, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5F55
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STRUCTURE OF RECJ COMPLEXED WITH DNA
Descriptor:Single-stranded-DNA-specific exonuclease, DNA (5'-D(*GP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*C)-3'), SULFATE ION, ...
Authors:Hua, Y., Zhao, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5F54
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STRUCTURE OF RECJ COMPLEXED WITH DTMP
Descriptor:Single-stranded-DNA-specific exonuclease, MANGANESE (II) ION, THYMIDINE-5'-PHOSPHATE
Authors:Hua, Y., Zhao, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5CEZ
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CRYSTAL STRUCTURE OF THE BG505 SOSIP GP140 HIV-1 ENV TRIMER IN COMPLEX WITH AN EARLY PUTATIVE PRECURSOR OF THE PGT121 FAMILY AT 3.0 ANGSTROM
Descriptor:Envelope glycoprotein gp160, 3H+109L Fab Light Chain, 3H+109L Fab Heavy Chain, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-08
Release date:2015-12-23
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEY
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CRYSTAL STRUCTURE OF FAB 9H+3L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, GLYCEROL, ...
Authors:Wilson, I.A., Garces, F.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.387 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEX
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CRYSTAL STRUCTURE OF FAB 32H+109L, A PUTATIVE PRECURSOR OF THE PGT121 FAMILY OF POTENT HIV-1 ANTIBODIES
Descriptor:Antibody 9H+3L Fab light chain, Antibody 9H+3L Fab heavy chain, TETRAETHYLENE GLYCOL, ...
Authors:Garces, F., Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2016-01-06
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CD5
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CRYSTAL STRUCTURE OF AN IMMATURE VRC01-CLASS ANTIBODY DRVIA7 FROM A CHINESE DONOR BOUND TO CLADE A/E HIV-1 GP120 CORE
Descriptor:93TH057 HIV-1 gp120 core, DRVIA7 Fab Heavy Chain, DRVIA7 Fab Light Chain, ...
Authors:Kong, L., Wilson, I.A.
Deposit date:2015-07-03
Release date:2016-04-06
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (3.396 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5CD3
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STRUCTURE OF IMMATURE VRC01-CLASS ANTIBODY DRVIA7
Descriptor:DRVIA7 Heavy Chain, DRVIA7 Light Chain
Authors:Kong, L., Wilson, I.A.
Deposit date:2015-07-02
Release date:2016-04-06
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5C7K
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CRYSTAL STRUCTURE BG505 SOSIP GP140 HIV-1 ENV TRIMER BOUND TO BROADLY NEUTRALIZING ANTIBODIES PGT128 AND 8ANC195
Descriptor:Antibody Fab PGT128 heavy chain, Antibody Fab PGT128 light chain, Envelope glycoprotein gp120, ...
Authors:Kong, L., Stanfield, R.L., Wilson, I.A.
Deposit date:2015-06-24
Release date:2015-10-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (4.6019 Å)
Cite:Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5BX5
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH GLUCOSE
Descriptor:beta-glucosidase, BETA-D-GLUCOSE, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Hua, Y., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX4
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH GLUCOIMIDAZOLE
Descriptor:beta-glucosidase, GLUCOIMIDAZOLE, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tankrathok, A., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX3
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH DEOXYNOJIRIMYCIN
Descriptor:beta-glucosidase, 1-DEOXYNOJIRIMYCIN, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tankrathok, A., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5BX2
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH 2-DEOXY-2-FLUOROGLUCOSIDE
Descriptor:beta-glucosidase, 2-deoxy-2-fluoro-alpha-D-glucopyranose, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
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