Author results

5F54
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STRUCTURE OF RECJ COMPLEXED WITH DTMP
Descriptor:Single-stranded-DNA-specific exonuclease, MANGANESE (II) ION, THYMIDINE-5'-PHOSPHATE
Authors:Hua, Y., Zhao, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5F55
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STRUCTURE OF RECJ COMPLEXED WITH DNA
Descriptor:Single-stranded-DNA-specific exonuclease, DNA (5'-D(*GP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*C)-3'), SULFATE ION, ...
Authors:Hua, Y., Zhao, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
3WBA
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RICE OS3BGLU6 E178Q WITH COVALENT GLUCOSYL MOIETY FROM P-NITROPHENYL GLUCOPYRANOSIDE.
Descriptor:Beta-glucosidase 6, ALPHA-D-GLUCOSE, GLYCEROL
Authors:Sansenya, S., Hua, Y., Cairns, J.R.K.
Deposit date:2013-05-14
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enzymatic and structural characterization of hydrolysis of gibberellin A4 glucosyl ester by a rice beta-d-glucosidase
Arch.Biochem.Biophys., 537, 2013
3WBE
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RICE OS3BGLU6 BETA-GLUCOSIDASE E178Q MUTANT IN A COVALENT COMPLEX WITH GLC FROM GA4GE.
Descriptor:Beta-glucosidase 6, ALPHA-D-GLUCOSE, GLYCEROL
Authors:Sansenya, S., Hua, Y., Cairns, J.R.K.
Deposit date:2013-05-14
Release date:2013-09-04
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Enzymatic and structural characterization of hydrolysis of gibberellin A4 glucosyl ester by a rice beta-d-glucosidase
Arch.Biochem.Biophys., 537, 2013
6JQ1
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CRYSTAL STRUCTURE OF DDRO FROM DEINOCOCCUS GEOTHERMALIS
Descriptor:Transcriptional regulator, XRE family, LITHIUM ION
Authors:Lu, H., Hua, Y., Zhao, Y.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO.
Nucleic Acids Res., 47, 2019
6MO0
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine
Authors:Lin, Y.-L., Nie, S., Hua, Y., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J. Am. Chem. Soc., 141, 2019
6MO1
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine
Authors:Lin, Y.-L., Hua, Y., Nie, S., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
6MO2
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STRUCTURE OF DENGUE VIRUS PROTEASE WITH AN ALLOSTERIC INHIBITOR THAT BLOCKS REPLICATION
Descriptor:FLAVIVIRUS_NS2B/Peptidase S7, 1-(4-{5-[(piperidin-4-yl)methoxy]-3-[4-(1H-pyrazol-4-yl)phenyl]pyrazin-2-yl}phenyl)methanamine
Authors:Lin, Y.-L., Nie, S., Hua, Y., Wu, J., Wu, F., Huo, T., Yao, Y., Song, Y.
Deposit date:2018-10-03
Release date:2019-05-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
J.Am.Chem.Soc., 141, 2019
4XWT
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CRYSTAL STRUCTURE OF RNASE J COMPLEXED WITH UMP
Descriptor:DR2417, ZINC ION, MANGANESE (II) ION, ...
Authors:Lu, M., Zhang, H., Xu, Q., Hua, Y., Zhao, Y.
Deposit date:2015-01-29
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
4XWW
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CRYSTAL STRUCTURE OF RNASE J COMPLEXED WITH RNA
Descriptor:DR2417, RNA (5'-D(UP*UP*UP*UP*UP*UP*U)-3'), ZINC ION, ...
Authors:Lu, M., Zhang, H., Xu, Q., Hua, Y., Zhao, Y.
Deposit date:2015-01-29
Release date:2015-12-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
5F56
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STRUCTURE OF RECJ COMPLEXED WITH DNA AND SSB-CT
Descriptor:Single-stranded-DNA-specific exonuclease, DNA (5'-D(*CP*TP*GP*AP*TP*GP*GP*CP*A)-3'), ALA-ASP-LEU-PRO-PHE, ...
Authors:Zhao, Y., Hua, Y., Cheng, K.
Deposit date:2015-12-04
Release date:2016-06-15
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for DNA 5 -end resection by RecJ
Elife, 5, 2016
5H7E
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CRYSTAL STRUCTURE OF NATIVE DRCPDASE
Descriptor:RNA 2',3'-cyclic phosphodiesterase, GLYCEROL, SULFATE ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2016-11-18
Release date:2017-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the RNA 2',3'-cyclic phosphodiesterase from Deinococcus radiodurans
Acta Crystallogr F Struct Biol Commun, 73, 2017
5H7F
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CRYSTAL STRUCTURE OF MN-DERIVATIVE DRCPDASE
Descriptor:RNA 2',3'-cyclic phosphodiesterase, SULFATE ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2016-11-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal Structure of Mn-derivative drCPDase
To be published
5ZOD
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CRYSTAL STRUCTURE OF HFEN1 IN APO FORM
Descriptor:Flap endonuclease 1, MAGNESIUM ION, POTASSIUM ION
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOE
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CRYSTAL STRUCTURE OF D181A HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOF
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CRYSTAL STRUCTURE OF D181A/R192F HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), DNA (5'-D(*GP*CP*CP*CP*GP*TP*CP*C)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
5ZOG
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CRYSTAL STRUCTURE OF R192F HFEN1 IN COMPLEX WITH DNA
Descriptor:Flap endonuclease 1, DNA (5'-D(*CP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*TP*CP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*G)-3'), ...
Authors:Han, W., Hua, Y., Zhao, Y.
Deposit date:2018-04-13
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1.
Nucleic Acids Res., 46, 2018
1CB3
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LOCAL INTERACTIONS DRIVE THE FORMATION OF NON-NATIVE STRUCTURE IN THE DENATURED STATE OF HUMAN ALPHA-LACTALBUMIN: A HIGH RESOLUTION STRUCTURAL CHARACTERIZATION OF A PEPTIDE MODEL IN AQUEOUS SOLUTION
Descriptor:PROTEIN (LCA)
Authors:Demarest, S.J., Hua, Y., Raleigh, D.P.
Deposit date:1999-02-26
Release date:1999-06-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Local interactions drive the formation of nonnative structure in the denatured state of human alpha-lactalbumin: a high resolution structural characterization of a peptide model in aqueous solution.
Biochemistry, 38, 1999
1DMC
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THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF CALLINECTES SAPIDUS METALLOTHIONEIN-I DETERMINED BY HOMONUCLEAR AND HETERONUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor:CD6 METALLOTHIONEIN-1, CADMIUM ION
Authors:Narula, S.S., Brouwer, M., Hua, Y., Armitage, I.M.
Deposit date:1994-11-22
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Callinectes sapidus metallothionein-1 determined by homonuclear and heteronuclear magnetic resonance spectroscopy.
Biochemistry, 34, 1995
1DMD
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THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF CALLINECTES SAPIDUS METALLOTHIONEIN-I DETERMINED BY HOMONUCLEAR AND HETERONUCLEAR MAGNETIC RESONANCE SPECTOSCOPY
Descriptor:CD6 METALLOTHIONEIN-1, CADMIUM ION
Authors:Narula, S.S., Brouwer, M., Hua, Y., Armitage, I.M.
Deposit date:1994-11-22
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Callinectes sapidus metallothionein-1 determined by homonuclear and heteronuclear magnetic resonance spectroscopy.
Biochemistry, 34, 1995
1DME
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THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF CALLINECTES SAPIDUS METALLOTHIONEIN-I DETERMINED BY HOMONUCLEAR AND HETERONUCLEAR MAGNETIC RESONANCE SPECTOSCOPY
Descriptor:CD6 METALLOTHIONEIN-1, CADMIUM ION
Authors:Narula, S.S., Brouwer, M., Hua, Y., Armitage, I.M.
Deposit date:1994-11-22
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Callinectes sapidus metallothionein-1 determined by homonuclear and heteronuclear magnetic resonance spectroscopy.
Biochemistry, 34, 1995
1DMF
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THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF CALLINECTES SAPIDUS METALLOTHIONEIN-I DETERMINED BY HOMONUCLEAR AND HETERONUCLEAR MAGNETIC RESONANCE SPECTOSCOPY
Descriptor:CD6 METALLOTHIONEIN-1, CADMIUM ION
Authors:Narula, S.S., Brouwer, M., Hua, Y., Armitage, I.M.
Deposit date:1994-11-22
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Callinectes sapidus metallothionein-1 determined by homonuclear and heteronuclear magnetic resonance spectroscopy.
Biochemistry, 34, 1995
5BX5
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CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH GLUCOSE
Descriptor:beta-glucosidase, BETA-D-GLUCOSE, GLYCEROL, ...
Authors:Charoenwattanasatien, R., Pengthaisong, S., Sansenya, S., Mutoh, R., Hua, Y., Tanaka, H., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-06-08
Release date:2016-05-18
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Bacterial beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)
Acs Chem.Biol., 11, 2016
5FJS
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BACTERIAL BETA-GLUCOSIDASE REVEALS THE STRUCTURAL AND FUNCTIONAL BASIS OF GENETIC DEFECTS IN HUMAN GLUCOCEREBROSIDASE 2 (GBA2)
Descriptor:GLUCOSYLCERAMIDASE, CALCIUM ION
Authors:Charoenwattanasatien, R., Pengthaisong, S., Breen, I., Mutoha, R., Sansenya, S., Hua, Y., Tankrathok, A., Wu, L., Songsiriritthigul, C., Tanaka, H., Williams, S.J., Davies, G.J., Kurisu, G., Ketudat Cairns, J.R.
Deposit date:2015-10-12
Release date:2016-05-11
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bacterial Beta-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (Gba2)
Acs Chem.Biol., 11, 2016
1CQU
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9
Descriptor:50S RIBOSOMAL PROTEIN L9
Authors:Hua, Y., Kuhlman, B., Hoffman, D., Raleigh, D.P.
Deposit date:1999-08-11
Release date:2002-04-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of varying the local propensity to form secondary structure on the stability and folding kinetics of a rapid folding mixed alpha/beta protein: characterization of a truncation mutant of the N-terminal domain of the ribosomal protein L9.
J.Mol.Biol., 289, 1999
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