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4DS0
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BU of 4ds0 by Molmil
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen
Descriptor: Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V.
Deposit date:2012-02-17
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.
Nature, 485, 2012
4DRV
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BU of 4drv by Molmil
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen
Descriptor: Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose
Authors:Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V.
Deposit date:2012-02-17
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.
Nature, 485, 2012
4DRR
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BU of 4drr by Molmil
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen
Descriptor: Outer capsid protein VP4, SODIUM ION
Authors:Hu, L, Crawford, S.E, Czako, R, Cortes-Penfield, N.W, Smith, D.F, Le Pendu, J, Estes, M.K, Prasad, B.V.V.
Deposit date:2012-02-17
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.
Nature, 485, 2012
5D9Y
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BU of 5d9y by Molmil
Crystal structure of TET2-5fC complex
Descriptor: DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-19
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
5DEU
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BU of 5deu by Molmil
Crystal structure of TET2-5hmC complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ...
Authors:Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y.
Deposit date:2015-08-26
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
7RSW
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BU of 7rsw by Molmil
Crystal structure of group B human rotavirus VP8*
Descriptor: Outer capsid protein VP4, peptide
Authors:Hu, L, Salmen, W, Sankaran, B, Prasad, B.V.
Deposit date:2021-08-11
Release date:2022-07-20
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography.
Commun Biol, 5, 2022
8G0W
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BU of 8g0w by Molmil
Crystal structure of human norovirus GII.4 P domain in complex with Nanobody M4
Descriptor: Nanobody M4, VP1
Authors:Hu, L, Salmen, W, Sankaran, B, Prasad, B.V.V.
Deposit date:2023-02-01
Release date:2023-10-04
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Crystal structure of human norovirus GII.4 P domain in complex with Nanobody M4
To Be Published
7K6V
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BU of 7k6v by Molmil
Crystal Structure of Virus-like Particles of GII.4 Norovirus Houston virus (HOV)
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2020-09-21
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of GII.4 Norovirus capsid reveals inherent conformational flexibility of the capsid protein
To Be Published
4NM6
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BU of 4nm6 by Molmil
Crystal structure of TET2-DNA complex
Descriptor: 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', FE (II) ION, Methylcytosine dioxygenase TET2, ...
Authors:Hu, L, Li, Z, Cheng, J, Rao, Q, Gong, W, Liu, M, Wang, P, Xu, Y.
Deposit date:2013-11-14
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.026 Å)
Cite:Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
4YG0
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BU of 4yg0 by Molmil
Structural basis of glycan recognition in neonate-specific rotaviruses
Descriptor: Outer capsid protein VP4, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2015-02-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.285 Å)
Cite:Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun, 6, 2015
4YG3
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BU of 4yg3 by Molmil
Structural basis of glycan recognition in neonate-specific rotaviruses
Descriptor: Outer capsid protein VP4, SULFATE ION
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2015-02-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun, 6, 2015
4YG6
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BU of 4yg6 by Molmil
Structural basis of glycan recognition in neonate-specific rotaviruses
Descriptor: Outer capsid protein VP8*, PHOSPHATE ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2015-02-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun, 6, 2015
4YFW
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BU of 4yfw by Molmil
Structural basis of glycan recognition in neonate-specific rotaviruses
Descriptor: Outer capsid protein VP4
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2015-02-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun, 6, 2015
4YFZ
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BU of 4yfz by Molmil
Structural basis of glycan recognition in neonate-specific rotaviruses
Descriptor: Outer capsid protein VP4, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2015-02-25
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun, 6, 2015
4G0A
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BU of 4g0a by Molmil
Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity
Descriptor: CHLORIDE ION, Non-structural protein 2, RNA (5'-R(P*GP*GP*U)-3'), ...
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2012-07-09
Release date:2012-08-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.0995 Å)
Cite:Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
J.Virol., 86, 2012
4G0J
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BU of 4g0j by Molmil
Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity
Descriptor: Non-structural protein 2
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2012-07-09
Release date:2012-08-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.398 Å)
Cite:Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
J.Virol., 86, 2012
3SHB
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BU of 3shb by Molmil
Crystal Structure of PHD Domain of UHRF1
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3 peptide, ZINC ION
Authors:Hu, L, Li, Z, Wang, P, Lin, Y, Xu, Y.
Deposit date:2011-06-16
Release date:2011-08-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2.
Cell Res., 2011
2KOW
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BU of 2kow by Molmil
Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by Giardia telomeric repeat d(TAGGG)4 in K+ solution (with G18-to-INO substitution)
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*GP*GP*GP*TP*AP*IP*GP*G)-3')
Authors:Hu, L, Lim, K.W, Bouaziz, S, Phan, A.T.
Deposit date:2009-10-02
Release date:2009-11-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Giardia Telomeric Sequence d(TAGGG)(4) Forms Two Intramolecular G-Quadruplexes in K(+) Solution: Effect of Loop Length and Sequence on the Folding Topology.
J.Am.Chem.Soc., 131, 2009
5VX9
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BU of 5vx9 by Molmil
VP8* of P[6] Human Rotavirus RV3 in complex with LNFP1
Descriptor: Outer capsid protein VP4, SULFATE ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hu, L, Venkataram Prasad, B.V.
Deposit date:2017-05-23
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.822 Å)
Cite:Glycan recognition in globally dominant human rotaviruses.
Nat Commun, 9, 2018
5VX4
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BU of 5vx4 by Molmil
VP8* of a G2P[4] Human Rotavirus
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Outer capsid protein VP4
Authors:Hu, L, Venkataram Prasad, B.V.
Deposit date:2017-05-23
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Glycan recognition in globally dominant human rotaviruses.
Nat Commun, 9, 2018
5VX8
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BU of 5vx8 by Molmil
VP8* of P[6] Human Rotavirus RV3
Descriptor: Outer capsid protein VP4, SULFATE ION
Authors:Hu, L, Venkataram Prasad, B.V.
Deposit date:2017-05-23
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Glycan recognition in globally dominant human rotaviruses.
Nat Commun, 9, 2018
5VX5
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BU of 5vx5 by Molmil
VP8* of a G2P[4] Human Rotavirus in complex with LNFP1
Descriptor: Outer capsid protein VP4, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Hu, L, Venkataram Prasad, B.V.
Deposit date:2017-05-23
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.285 Å)
Cite:Glycan recognition in globally dominant human rotaviruses.
Nat Commun, 9, 2018
4RPT
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BU of 4rpt by Molmil
The 1.35A structure of a viral RNase L antagonist reveals basis for the 2'-5'-oligoadenylate binding and enzyme activity.
Descriptor: 1,2-ETHANEDIOL, Capping enzyme protein, MALONATE ION
Authors:Hu, L, Prasad, B.V.V.
Deposit date:2014-10-31
Release date:2015-04-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.
J.Virol., 89, 2015
6PCU
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BU of 6pcu by Molmil
VP8* of a G2P[4] human rotavirus in complex with scFv antibody 9
Descriptor: GLYCEROL, Outer capsid protein VP4, SULFATE ION, ...
Authors:Hu, L, Venkataram Prasad, B.V.
Deposit date:2019-06-18
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells.
J.Clin.Invest., 130, 2019
7MRY
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BU of 7mry by Molmil
Norovirus T=3 GII.4 HOV VLP
Descriptor: VP1
Authors:Salmen, W, Hu, L, Prasad, B.
Deposit date:2021-05-10
Release date:2022-03-02
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity.
Nat Commun, 13, 2022

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