Author results

1RPY
  • Download 1rpy
  • View 1rpy
Molmil generated image of 1rpy
CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS
Descriptor:adaptor protein APS, SULFATE ION
Authors:Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.
Deposit date:2003-12-03
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
1RQQ
  • Download 1rqq
  • View 1rqq
Molmil generated image of 1rqq
CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH THE SH2 DOMAIN OF APS
Descriptor:Insulin receptor, adaptor protein APS, BISUBSTRATE INHIBITOR, ...
Authors:Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.
Deposit date:2003-12-06
Release date:2003-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
2QLD
  • Download 2qld
  • View 2qld
Molmil generated image of 2qld
HUMAN HSP40 HDJ1
Descriptor:DnaJ homolog subfamily B member 1
Authors:Hu, J., Wu, Y., Li, J., Fu, Z., Sha, B.
Deposit date:2007-07-12
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
3H84
  • Download 3h84
  • View 3h84
Molmil generated image of 3h84
CRYSTAL STRUCTURE OF GET3
Descriptor:ATPase GET3, ZINC ION, MAGNESIUM ION, ...
Authors:Hu, J., Li, J., Qian, X., Sha, B.
Deposit date:2009-04-28
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.
Plos One, 4, 2009
3IO3
  • Download 3io3
  • View 3io3
Molmil generated image of 3io3
GET3 WITH ADP FROM D. HANSENII IN CLOSED FORM
Descriptor:DEHA2D07832p, ADENOSINE-5'-DIPHOSPHATE, ZINC ION, ...
Authors:Hu, J., Li, J., Qian, X., Sha, B.
Deposit date:2009-08-13
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion
Plos One, 4, 2009
4TZ7
  • Download 4tz7
  • View 4tz7
Molmil generated image of 4tz7
CRYSTAL STRUCTURE OF TYPE I PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE ALPHA FROM ZEBRAFISH
Descriptor:Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Authors:Hu, J., Qin, Y., Wang, J., Li, L., Wu, D., Ha, Y.
Deposit date:2014-07-09
Release date:2015-09-02
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
Nat Commun, 6, 2015
1YVH
  • Download 1yvh
  • View 1yvh
Molmil generated image of 1yvh
CRYSTAL STRUCTURE OF THE C-CBL TKB DOMAIN IN COMPLEX WITH THE APS PTYR-618 PHOSPHOPEPTIDE
Descriptor:CBL E3 ubiquitin protein ligase, 13-mer fragment of SH2 and PH domain-containing adapter protein APS, MAGNESIUM ION
Authors:Hu, J., Hubbard, S.R.
Deposit date:2005-02-15
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins
J.Biol.Chem., 280, 2005
2H95
  • Download 2h95
  • View 2h95
Molmil generated image of 2h95
STRUCTURE OF THE AMANTADINE-BLOCKED INFLUENZA A M2 PROTON CHANNEL TRANS-MEMBRANE DOMAIN BY SOLID-STATE NMR SPECTROSCOPY
Descriptor:Matrix protein 2
Authors:Hu, J., Asbury, T., Cross, T.A.
Deposit date:2006-06-08
Release date:2007-04-24
Last modified:2011-07-13
Method:SOLID-STATE NMR
Cite:Backbone structure of the amantadine-blocked trans-membrane domain m2 proton channel from influenza a virus.
Biophys.J., 92, 2007
2HDV
  • Download 2hdv
  • View 2hdv
Molmil generated image of 2hdv
CRYSTAL STRUCTURE OF THE SRC HOMOLOGY-2 DOMAIN OF THE ADAPTER PROTEIN SH2-B
Descriptor:SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J., Hubbard, S.R.
Deposit date:2006-06-20
Release date:2006-08-08
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDX
  • Download 2hdx
  • View 2hdx
Molmil generated image of 2hdx
CRYSTAL STRUCTURE OF THE SRC HOMOLOGY-2 DOMAIN OF SH2-B IN COMPLEX WITH JAK2 PTYR813 PHOSPHOPEPTIDE
Descriptor:SH2-B PH domain containing signaling mediator 1 gamma isoform, Jak2 protein
Authors:Hu, J., Hubbard, S.R.
Deposit date:2006-06-21
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
3S0X
  • Download 3s0x
  • View 3s0x
Molmil generated image of 3s0x
THE CRYSTAL STRUCTURE OF GXGD MEMBRANE PROTEASE FLAK
Descriptor:Peptidase A24B, FlaK domain protein
Authors:Hu, J., Xue, Y., Ha, Y.
Deposit date:2011-05-13
Release date:2011-08-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of GXGD membrane protease FlaK.
Nature, 475, 2011
5TDE
  • Download 5tde
  • View 5tde
Molmil generated image of 5tde
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO CITRATE
Descriptor:ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDF
  • Download 5tdf
  • View 5tdf
Molmil generated image of 5tdf
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO 4S HYDROXYCITRATE
Descriptor:ATP-citrate synthase, 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDM
  • Download 5tdm
  • View 5tdm
Molmil generated image of 5tdm
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO 4R-HYDROXYCITRATE AND ADP
Descriptor:ATP-citrate synthase, 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-19
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDZ
  • Download 5tdz
  • View 5tdz
Molmil generated image of 5tdz
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO TARTRATE AND ADP
Descriptor:ATP-citrate synthase, L(+)-TARTARIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-20
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TE1
  • Download 5te1
  • View 5te1
Molmil generated image of 5te1
C20S, C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO 4R-HYDROXYCITRATE
Descriptor:ATP-citrate synthase, 3-C-carboxy-2-deoxy-L-threo-pentaric acid, PHOSPHATE ION, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-20
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TEQ
  • Download 5teq
  • View 5teq
Molmil generated image of 5teq
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
Descriptor:ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TES
  • Download 5tes
  • View 5tes
Molmil generated image of 5tes
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO CITRATE AND ADP
Descriptor:ATP-citrate synthase, CITRATE ANION, MAGNESIUM ION, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TET
  • Download 5tet
  • View 5tet
Molmil generated image of 5tet
TEV CLEAVED HUMAN ATP CITRATE LYASE BOUND TO 4S HYDROXYCITRATE
Descriptor:ATP-citrate synthase, 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, PHOSPHATE ION, ...
Authors:Hu, J., Fraser, M.E.
Deposit date:2016-09-22
Release date:2017-08-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5YDU
  • Download 5ydu
  • View 5ydu
Molmil generated image of 5ydu
CRYSTAL STRUCTURE OF UTP30
Descriptor:Ribosome biogenesis protein UTP30, PHOSPHATE ION
Authors:Hu, J., Zhu, X., Ye, K.
Deposit date:2017-09-14
Release date:2017-11-01
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
6DUZ
  • Download 6duz
  • View 6duz
Molmil generated image of 6duz
STRUCTURE OF THE PERIPLASMIC DOMAINS OF PRGH AND PRGK FROM THE ASSEMBLED SALMONELLA TYPE III SECRETION INJECTISOME NEEDLE COMPLEX
Descriptor:Protein PrgH, Lipoprotein PrgK
Authors:Hu, J., Worrall, L.J., Vuckovic, M., Atkinson, C.E., Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV3
  • Download 6dv3
  • View 6dv3
Molmil generated image of 6dv3
STRUCTURE OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME SECRETIN INVG IN THE OPEN GATE STATE
Descriptor:Protein InvG
Authors:Hu, J., Worrall, L.J., Vuckovic, M., Atkinson, C.E., Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV6
  • Download 6dv6
  • View 6dv6
Molmil generated image of 6dv6
STRUCTURE OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME SECRETIN INVG (RESIDUES 176-END) IN THE OPEN GATE STATE
Descriptor:Protein InvG
Authors:Hu, J., Worrall, L.J., Vuckovic, M., Atkinson, C.E., Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DWB
  • Download 6dwb
  • View 6dwb
Molmil generated image of 6dwb
STRUCTURE OF THE SALMONELLA SPI-1 TYPE III SECRETION INJECTISOME NEEDLE FILAMENT
Descriptor:Protein PrgI
Authors:Hu, J., Hong, C., Worrall, L.J., Vuckovic, M., Yu, Z., Strynadka, N.C.J.
Deposit date:2018-06-26
Release date:2018-10-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
1VSQ
  • Download 1vsq
  • View 1vsq
Molmil generated image of 1vsq
SOLUTION NMR STRUCTURE OF THE PRODUCTIVE COMPLEX BETWEEN IIAMANNOSE AND IIBMANNOSE OF THE MANNOSE TRANSPORTER OF THE E. COLI PHOSPHOTRANSFERASE SYSTEM
Descriptor:Mannose-specific phosphotransferase enzyme IIA component, Mannose-specific phosphotransferase enzyme IIB component
Authors:Clore, G.M., Hu, J., Hu, K.
Deposit date:2008-01-10
Release date:2008-02-19
Last modified:2018-10-03
Method:SOLUTION NMR
Cite:Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008