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1Z1J
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CRYSTAL STRUCTURE OF SARS 3CLPRO C145A MUTANT
Descriptor:3C-like proteinase
Authors:Hsu, M.F.
Deposit date:2005-03-04
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Understanding the maturation process and inhibitor design of SARS-CoV 3CLpro from the crystal structure of C145A in a product-bound form
J.Biol.Chem., 280, 2005
3KCW
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CRYSTAL STRUCTURE OF GANODERMA FUNGAL IMMUNOMODULATORY PROTEIN, GMI
Descriptor:immunomodulatory protein
Authors:Hsu, M.F., Wang, A.H.J., Yang, C.S., Huang, C.T., Hseu, R.S., Lin, C.W., Wu, M.Y., Huang, C.S., Fu, H.Y.
Deposit date:2009-10-22
Release date:2010-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Single cysteine replacement at Leu6 increase the potent and thermostability in Ganoderma fungal immunomodulatory proteins
To be Published
2GX4
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS 3CL PROTEASE INHIBITOR COMPLEX
Descriptor:3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE
Authors:Hsu, M.F., Wang, A.H.-J.
Deposit date:2006-05-08
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure-based design of SARS coronavirus 3CL protease inhibitor with potent anti_viral activities
To be Published
2ZU4
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COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0204998
Descriptor:3C-like proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide
Authors:Hsu, M.F., Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU5
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COMPLEX STRUCTURE OF SARS-COV 3CL PROTEASE WITH TG-0205486
Descriptor:3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-[(1R)-4-cyclopropyl-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}butyl]-L-leucinamide
Authors:Hsu, M.F., Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
4QI1
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CRYSTAL STRUCTURE OF H. WALSBYI BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin-I, RETINAL, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate, ...
Authors:Wang, A.H.J., Hsu, M.F., Yang, C.S., Fu, H.Y.
Deposit date:2014-05-30
Release date:2015-07-29
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity.
J. Biol. Chem., 290, 2015
4WAV
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CRYSTAL STRUCTURE OF HALOQUADRATUM WALSBYI BACTERIORHODOPSIN MUTANT D93N
Descriptor:Bacteriorhodopsin-I, RETINAL, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
Authors:Wang, A.H.J., Hsu, M.F., Yang, C.S., Fu, H.Y.
Deposit date:2014-09-02
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of an acid-tolerant light-driven proton pump at 1.85 Angstroms resolution
To be published
4QID
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CRYSTAL STRUCTURE OF HALOQUADRATUM WALSBYI BACTERIORHODOPSIN
Descriptor:Bacteriorhodopsin-I, RETINAL, ACETATE ION, ...
Authors:Wang, A.H.J., Hsu, M.F., Yang, C.S., Fu, H.Y.
Deposit date:2014-05-30
Release date:2015-07-29
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:An acid-tolerant light-driven proton pump
To be Published
1Z1I
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CRYSTAL STRUCTURE OF NATIVE SARS CLPRO
Descriptor:3C-like proteinase
Authors:Liang, P.H., Wang, A.H.
Deposit date:2005-03-04
Release date:2005-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Understanding the maturation process and inhibitor design of SARS-CoV 3CLpro from the crystal structure of C145A in a product-bound form
J.Biol.Chem., 280, 2005
2ZTX
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COMPLEX STRUCTURE OF CVB3 3C PROTEASE WITH EPDTC
Descriptor:3C proteinase, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZTY
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM CVB3 IN SPACE GROUP C2
Descriptor:3C proteinase
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZTZ
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM CVB3 IN SPACE GROUP P21
Descriptor:3C proteinase
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-11
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU1
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CRYSTAL STRUCTURE OF CVB3 3C PROTEASE MUTANT C147A
Descriptor:3C proteinase
Authors:Lee, C.C., Tsui, Y.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU2
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COMPLEX STRUCTURE OF COV 229E 3CL PROTEASE WITH EPDTC
Descriptor:3C-like proteinase, (4S)-2-METHYL-2,4-PENTANEDIOL, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZU3
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COMPLEX STRUCTURE OF CVB3 3C PROTEASE WITH TG-0204998
Descriptor:3C proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide
Authors:Lee, C.C., Tsui, Y.C., Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2Z94
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH TDT
Descriptor:Replicase polyprotein 1ab, ZINC ION, 4-methylbenzene-1,2-dithiol
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-17
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors
Febs Lett., 581, 2007
2Z9G
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH PMA
Descriptor:3C-like proteinase, MERCURY (II) ION, BENZENE
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-19
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9J
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH EPDTC
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9K
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1600
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, (dimethylamino)(hydroxy)zinc'
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9L
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COMPLEX STRUCTURE OF SARS-COV 3C-LIKE PROTEASE WITH JMF1586
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE, diaminozinc
Authors:Lee, C.C., Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007