Author results

2W4F
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CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1
分子名称:PROTEIN LAP4, 1,2-ETHANEDIOL
著者Hozjan, V., Pilka, E.S., Roos, A.K., W Yue, W., Phillips, C., Bray, J., Cooper, C., Salah, E., Elkins, J.M., Muniz, J.R.C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., von Delft, F., Bountra, C., Doyle, D.A., Oppermann, U.
登録日2008-11-25
公開日2008-12-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
2H5G
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE SYNTHETASE
分子名称:Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION
著者Papagrigoriou, E., Shafqat, N., Turnbull, A.P., Berridge, G., Hozjan, V., Kavanagh, K., Gileadi, O., Smee, C., Bray, J., Gorrec, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-05-26
公開日2006-06-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of human pyrroline-5-carboxylate synthetase
To be published
2JFK
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STRUCTURE OF THE MAT DOMAIN OF HUMAN FAS WITH MALONYL-COA
分子名称:FATTY ACID SYNTHASE, COENZYME A
著者Bunkoczi, G., Kavanagh, K., Hozjan, V., Rojkova, A., Watt, S., Wu, X., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Smith, S., Oppermann, U.
登録日2007-02-02
公開日2007-03-13
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the MAT Domain of Human Fas with Malonyl-Coa
To be Published
2JIF
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STRUCTURE OF HUMAN SHORT-BRANCHED CHAIN ACYL-COA DEHYDROGENASE (ACADSB)
分子名称:SHORT/BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, COENZYME A PERSULFIDE, ...
著者Pike, A.C.W., Hozjan, V., Smee, C., Niesen, F.H., Kavanagh, K.L., Umeano, C., Turnbull, A.P., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Oppermann, U.
登録日2007-02-28
公開日2007-04-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Short-Branched Chain Acyl-Coa Dehydrogenase
To be Published
2OBV
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CRYSTAL STRUCTURE OF THE HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 1 IN COMPLEX WITH THE PRODUCT
分子名称:S-adenosylmethionine synthetase isoform type-1, SODIUM ION, S-ADENOSYLMETHIONINE, ...
著者Pilka, E.S., Shafqat, N., Kavanagh, K.L., Cooper, C., Hozjan, V., Turnbull, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-12-20
公開日2007-01-02
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
To be Published
2PLA
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CRYSTAL STRUCTURE OF HUMAN GLYCEROL-3-PHOSPHATE DEHYDROGENASE 1-LIKE PROTEIN
分子名称:Glycerol-3-phosphate dehydrogenase 1-like protein, PHOSPHATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Uppenberg, J., Smee, C., Hozjan, V., Kavanagh, K., Bunkoczi, G., Papagrigoriou, E., Pike, A.C.W., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-04-19
公開日2007-05-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein.
To be Published
2Q9V
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CRYSTAL STRUCTURE OF THE C890S MUTANT OF THE 4TH PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE
分子名称:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
著者Pilka, E.S., Hozjan, V., Kavanagh, K.L., Papagrigoriou, E., Cooper, C., Elkins, J.M., Doyle, D.A., von Delft, F., Sundstrom, M., Arrowsmith, C.A., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-06-14
公開日2007-06-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.
To be Published
2QIS
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CRYSTAL STRUCTURE OF HUMAN FARNESYL PYROPHOSPHATE SYNTHASE T210S MUTANT BOUND TO RISEDRONATE
分子名称:Farnesyl pyrophosphate synthetase, MAGNESIUM ION, 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID
著者Kavanagh, K.L., Dunford, J.E., Hozjan, V., Evdokimov, A., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-07-05
公開日2007-07-24
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate.
To be Published
2QQ5
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CRYSTAL STRUCTURE OF HUMAN SDR FAMILY MEMBER 1
分子名称:Dehydrogenase/reductase SDR family member 1
著者Pilka, E.S., Hozjan, V., Ugochukwu, E., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-07-26
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human SDR family member 1.
TO BE PUBLISHED
2R4H
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CRYSTAL STRUCTURE OF A C1190S MUTANT OF THE 6TH PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE
分子名称:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, HISTIDINE
著者Ugochukwu, E., Pilka, E.S., Hozjan, V., Kavanagh, K.L., Cooper, C., Pike, A.C.W., Elkins, J.M., Doyle, D.A., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-08-31
公開日2007-10-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase.
To be Published
2UXW
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CRYSTAL STRUCTURE OF HUMAN VERY LONG CHAIN ACYL-COA DEHYDROGENASE (ACADVL)
分子名称:VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Pike, A.C.W., Hozjan, V., Smee, C., Berridge, G., Burgess, N., Salah, E., Bunkoczi, G., Uppenberg, J., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
登録日2007-03-30
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
To be Published
2UYY
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STRUCTURE OF THE CYTOKINE-LIKE NUCLEAR FACTOR N-PAC
分子名称:N-PAC PROTEIN, POTASSIUM ION, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Tickle, J., Pilka, E.S., Bunkoczi, G., Berridge, G., Smee, C., Kavanagh, K.L., Hozjan, V., Niesen, F.H., Papagrigoriou, E., Pike, A.C.W., Turnbull, A., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., von Delft, F., Oppermann, U.
登録日2007-04-20
公開日2007-07-03
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of the Cytokine-Like Nuclear Factor N-Pac
To be Published
2WM3
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CRYSTAL STRUCTURE OF NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1 IN COMPLEX WITH NIFLUMIC ACID
分子名称:NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, ...
著者Bhatia, C., Yue, W.W., Niesen, F., Pilka, E., Ugochukwu, E., Savitsky, P., Hozjan, V., Roos, A.K., Filippakopoulos, P., von Delft, F., Heightman, T., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-06-29
公開日2009-08-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Nmra-Like Family Domain Containing Protein 1 in Complex with Niflumic Acid
To be Published
2WMD
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CRYSTAL STRUCTURE OF NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1 IN COMPLEX WITH NADP AND 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID
分子名称:NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1, 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bhatia, C., Pilka, E., Niesen, F., Yue, W.W., Ugochukwu, E., Savitsky, P., Hozjan, V., Roos, A.K., Filippakopoulos, P., von Delft, F., Heightman, T., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-06-30
公開日2009-07-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Nmra-Like Family Domain Containing Protein 1
To be Published
2WWU
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PHD FINGER PROTEIN 8
分子名称:PHD FINGER PROTEIN 8, SULFATE ION, ACETATE ION, ...
著者Yue, W.W., Hozjan, V., Cooper, C., Tumber, A., Krojer, T., Muniz, J., Allerston, C., Salah, E., McDonough, M.A., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Schofield, C.J., Kavanagh, K.L., Oppermann, U.
登録日2009-10-29
公開日2009-11-17
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
FEBS Lett., 584, 2010
3BPU
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CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT
分子名称:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, ZINC ION
著者Pilka, E.S., Hozjan, V., Cooper, C., Pike, A.C.W., Elkins, J., Doyle, D.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-12-19
公開日2008-01-08
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant.
To be Published
3GGE
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PDZ DOMAIN-CONTAINING PROTEIN GIPC2
分子名称:PDZ domain-containing protein GIPC2, SULFATE ION, GLYCEROL
著者Chaikuad, A., Hozjan, V., Yue, W., Cooper, C., Elkins, J., Pike, A.C.W., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2009-02-27
公開日2009-03-24
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the PDZ domain of PDZ domain-containing protein GIPC2
To be Published
4UYI
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CRYSTAL STRUCTURE OF THE BTB DOMAIN OF HUMAN SLX4 (BTBD12)
分子名称:STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4
著者Pinkas, D.M., Sanvitale, C.E., Strain-Damerell, C., Fairhead, M., Wang, D., Tallant, C., Cooper, C.D.O., Sorrell, F.J., Kopec, J., Chaikuad, A., Fitzpatrick, F., Pike, A.C.W., Hozjan, V., Ying, Z., Roos, A.K., Savitsky, P., Bradley, A., Nowak, R., Filippakopoulos, P., Krojer, T., Burgess-Brown, N.A., Marsden, B.D., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.
登録日2014-09-01
公開日2014-10-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the Btb Domain of Human Slx4 (Btbd12)
To be Published
2XN4
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CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL2 (MAYVEN)
分子名称:KELCH-LIKE PROTEIN 2, SODIUM ION, SULFATE ION, ...
著者Canning, P., Hozjan, V., Cooper, C.D.O., Ayinampudi, V., Vollmar, M., Pike, A.C.W., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.
登録日2010-07-30
公開日2010-08-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
6GY5
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CRYSTAL STRUCTURE OF THE KELCH DOMAIN OF HUMAN KLHL20 IN COMPLEX WITH DAPK1 PEPTIDE
分子名称:Kelch-like protein 20, Death-associated protein kinase 1, CHLORIDE ION, ...
著者Chen, Z., Hozjan, V., Strain-Damerell, C., Williams, E., Wang, D., Cooper, C.D.O., Sanvitale, C.E., Fairhead, M., Carpenter, E.P., Pike, A.C.W., Krojer, T., Srikannathasan, V., Sorrell, F., Johansson, C., Mathea, S., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.
登録日2018-06-28
公開日2018-08-08
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (1.086 Å)
主引用文献Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Structure, 27, 2019
2JFD
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STRUCTURE OF THE MAT DOMAIN OF HUMAN FAS
分子名称:FATTY ACID SYNTHASE
著者Bunkoczi, G., Kavanagh, K., Hozjan, V., Rojkova, A., Wu, X., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Weigelt, J., Smith, S., Oppermann, U.
登録日2007-01-31
公開日2007-02-13
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.
Chem. Biol., 16, 2009
5APA
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CRYSTAL STRUCTURE OF HUMAN ASPARTATE BETA-HYDROXYLASE ISOFORM A
分子名称:ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE, NICKEL (II) ION, (2S)-2-hydroxybutanedioic acid, ...
著者Krojer, T., Kochan, G., Pfeffer, I., McDonough, M.A., Pilka, E., Hozjan, V., Allerston, C., Muniz, J.R., Chaikuad, A., Gileadi, O., Kavanagh, K., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U.
登録日2015-09-15
公開日2015-09-23
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern.
Nat Commun, 10, 2019