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1H3I
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CRYSTAL STRUCTURE OF THE HISTONE METHYLTRANSFERASE SET7/9
Descriptor:HISTONE H3 LYSINE 4 SPECIFIC METHYLTRANSFERASE, MAGNESIUM ION
Authors:Wilson, J.R., Jing, C., Walker, P.A., Martin, S.R., Howell, S.A., Blackburn, G.M., Gamblin, S.J., Xiao, B.
Deposit date:2002-09-04
Release date:2002-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure and Functional Analysis of the Histone Methyltransferase Set7/9
Cell(Cambridge,Mass.), 111, 2002
2Y8L
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-07
Release date:2011-03-16
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-09
Release date:2011-03-16
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-17
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-18
Release date:2013-12-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2RJI
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MALARIAL EBA-175 REGION VI CRYSTALLOGRAPHIC STRUCTURE REVEALS A KIX-LIKE BINDING INTERFACE
Descriptor:Erythrocyte binding antigen 175, CALCIUM ION
Authors:Withers-Martinez, C., Blackman, M.J.
Deposit date:2007-10-15
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Malarial EBA-175 Region VI Crystallographic Structure Reveals a KIX-Like Binding Interface
J.Mol.Biol., 375, 2008
4LVN
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CRYSTAL STRUCTURE OF PFSUB1-PRODOMAIN-NIMP.M7 FAB COMPLEX
Descriptor:Subtilisin-like serine protease, NIMP.M7 Fab light chain, NIMP.M7 Fab heavy chain, ...
Authors:Withers-Martinez, C., Blackman, M.J.
Deposit date:2013-07-26
Release date:2014-05-07
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nat Commun, 5, 2014
4LVO
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CRYSTAL STRUCTURE OF PFSUB1-PRODOMAIN-NIMP.M7 FAB COMPLEX WITH ADDED CACL2
Descriptor:Subtilisin-like serine protease, NIMP.M7 Fab light chain, NIMP.M7 Fab heavy chain, ...
Authors:Withers-Martinez, C., Blackman, M.J.
Deposit date:2013-07-26
Release date:2014-05-07
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nat Commun, 5, 2014
4UYU
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I IODIDE COMPLEX - 2.3A
Descriptor:PROTEIN NOTUM HOMOLOG, N-ACETYL-D-GLUCOSAMINE, IODIDE ION, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UYW
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I HEPARIN FRAGMENT COMPLEX - 1.7A
Descriptor:PROTEIN NOTUM HOMOLOG, N-ACETYL-D-GLUCOSAMINE, HEPARIN DISACCHARIDE I-S
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UYZ
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM II - 2.8A
Descriptor:PROTEIN NOTUM HOMOLOG, POLY ALA, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ1
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM III - 1.4A
Descriptor:NOTUM, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ5
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A
Descriptor:NOTUM, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ6
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM V - SOS COMPLEX - 1.9A
Descriptor:PROTEIN NOTUM HOMOLOG, N-ACETYL-D-GLUCOSAMINE, SUCROSE OCTASULFATE, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ7
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A
Descriptor:PROTEIN NOTUM HOMOLOG, CHLORIDE ION
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZ9
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VII - SOS COMPLEX - 2.2A
Descriptor:PROTEIN NOTUM HOMOLOG, N-ACETYL-D-GLUCOSAMINE, SUCROSE OCTASULFATE, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZA
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VIII - PHOSPHATE COMPLEX - 2.4A
Descriptor:PROTEIN NOTUM HOMOLOG, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZJ
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STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM I - 2.4A
Descriptor:NOTUM, N-ACETYL-D-GLUCOSAMINE
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZK
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STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM II - 1.9A
Descriptor:NOTUM, N-ACETYL-D-GLUCOSAMINE
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZL
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I MYRISTOLEATE COMPLEX - 2.1A
Descriptor:PROTEIN NOTUM HOMOLOG, Myristoleic acid, N-ACETYL-D-GLUCOSAMINE
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-05
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4UZQ
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STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH O-PALMITOLEOYL SERINE - CRYSTAL FORM IX - 1.5A
Descriptor:PROTEIN NOTUM HOMOLOG, PROTEIN WNT-7A, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-07
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4WBH
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
Descriptor:Protein notum homolog, CHLORIDE ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zebisch, M., Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015
5AO0
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CRYSTAL STRUCTURE OF HUMAN SAMHD1 (AMINO ACID RESIDUES 41-583) BOUND TO DDGTP
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Schwefel, D., Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Method:X-RAY DIFFRACTION (3.731 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO1
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CRYSTAL STRUCTURE OF HUMAN SAMHD1 (AMINO ACID RESIDUES 115-583) BOUND TO DDGTP
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Schwefel, D., Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO2
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CRYSTAL STRUCTURE OF HUMAN SAMHD1 (AMINO ACID RESIDUES 115-583) R164A VARIANT BOUND TO DGTP
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
Authors:Schwefel, D., Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Method:X-RAY DIFFRACTION (2.966 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
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