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3N75
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X-RAY CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI INDUCIBLE LYSINE DECARBOXYLASE LDCI
Descriptor:Lysine decarboxylase, inducible, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
Authors:Kanjee, U., Alexopoulos, E., Pai, E.F., Houry, W.A.
Deposit date:2010-05-26
Release date:2011-02-16
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase.
Embo J., 30, 2011
5FL2
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REVISITED CRYO-EM STRUCTURE OF INDUCIBLE LYSINE DECARBOXYLASE COMPLEXED WITH LARA DOMAIN OF RAVA ATPASE
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE, ATPASE RAVA
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-21
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
1OVX
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NMR STRUCTURE OF THE E. COLI CLPX CHAPERONE ZINC BINDING DOMAIN DIMER
Descriptor:ATP-dependent Clp protease ATP-binding subunit clpX, ZINC ION
Authors:Donaldson, L.W., Kwan, J., Wojtyra, U., Houry, W.A.
Deposit date:2003-03-27
Release date:2003-12-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the dimeric zinc binding domain of the chaperone ClpX.
J.Biol.Chem., 278, 2003
1Y7O
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THE STRUCTURE OF STREPTOCOCCUS PNEUMONIAE A153P CLPP
Descriptor:ATP-dependent Clp protease proteolytic subunit, CALCIUM ION
Authors:Kimber, M.S., Gribun, A., Ching, R., Sprangers, R., Fiebig, K.M., Houry, W.A.
Deposit date:2004-12-09
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation.
J.Biol.Chem., 280, 2005
2L6J
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TAH1 COMPLEXED BY MEEVD
Descriptor:TPR repeat-containing protein associated with Hsp90, C-terminus Hsp90 chaperone peptide MEEVD
Authors:Jimenez, B., Ugwu, F., Zhao, R., Orti, L., Houry, W.A., Pineda-Lucena, A.
Deposit date:2010-11-22
Release date:2011-12-28
Last modified:2012-05-09
Method:SOLUTION NMR
Cite:Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90.
J.Biol.Chem., 287, 2012
3HLN
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CRYSTAL STRUCTURE OF CLPP A153C MUTANT WITH INTER-HEPTAMER DISULFIDE BONDS
Descriptor:ATP-dependent Clp protease proteolytic subunit, CALCIUM ION
Authors:Kimber, M.S., Yu, A.Y.H., Borg, M., Chan, H.S., Houry, W.A.
Deposit date:2009-05-27
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Theoretical Studies Indicate that the Cylindrical Protease ClpP Samples Extended and Compact Conformations.
Structure, 18, 2010
3Q16
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LINKAGE BETWEEN THE BACTERIAL ACID STRESS AND STRINGENT RESPONSES: THE STRUCTURE OF THE INDUCIBLE LYSINE DECARBOXYLASE
Descriptor:Lysine decarboxylase, inducible
Authors:El Bakkouri, M., Pai, E.F., Houry, W.A.
Deposit date:2010-12-16
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase.
Embo J., 30, 2011
4GM2
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THE CRYSTAL STRUCTURE OF A PEPTIDASE FROM PLASMODIUM FALCIPARUM
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:El Bakkouri, M., Jung, P., Wernimont, A.K., Calmettes, C., Hui, R., Houry, W.A., Structural Genomics Consortium (SGC)
Deposit date:2012-08-15
Release date:2012-12-05
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum.
J.Biol.Chem., 288, 2013
4HNK
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CRYSTAL STRUCTURE OF AN ENZYME
Descriptor:ATP-dependent Clp protease proteolytic subunit, GLYCEROL
Authors:El Bakkouri, M., Calmettes, C., Wernimont, A.K., Houry, W.A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2012-10-19
Release date:2012-12-05
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum.
J.Biol.Chem., 288, 2013
4UPB
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ELECTRON CRYO-MICROSCOPY OF THE COMPLEX FORMED BETWEEN THE HEXAMERIC ATPASE RAVA AND THE DECAMERIC INDUCIBLE DECARBOXYLASE LDCI
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE, ATPASE RAVA
Authors:Malet, H., Liu, K., El Bakkouri, M., Chan, S.W.S., Effantin, G., Bacia, M., Houry, W.A., Gutsche, I.
Deposit date:2014-06-15
Release date:2014-08-20
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins.
Elife, 3, 2014
4UPF
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ASSEMBLY PRINCIPLES OF THE UNIQUE CAGE FORMED BY THE ATPASE RAVA HEXAMER AND THE LYSINE DECARBOXYLASE LDCI DECAMER
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE, ATPASE RAVA
Authors:Malet, H., Liu, K., El Bakkouri, M., Chan, S.W.S., Effantin, G., Bacia, M., Houry, W.A., Gutsche, I.
Deposit date:2014-06-16
Release date:2014-08-20
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins.
Elife, 3, 2014
5DKP
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CRYSTAL STRUCTURE OF N. MENINGITIDIS CLPP IN COMPLEX WITH AGONIST ADEP A54556.
Descriptor:ATP-dependent Clp protease proteolytic subunit, agonist ADEP A54556, POTASSIUM ION, ...
Authors:Goodreid, J.D., Janetzko, J., Santa Maria Jr., J.P., Wong, K., Leung, E., Eger, B.T., Bryson, S., Pai, E.F., Gray-Owen, S.D., Walker, S., Houry, W.A., Batey, R.A.
Deposit date:2015-09-03
Release date:2016-01-27
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity.
J.Med.Chem., 59, 2016
5FKX
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STRUCTURE OF E.COLI INDUCIBLE LYSINE DECARBOXYLASE AT ACTIVE PH
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5FKZ
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STRUCTURE OF E.COLI CONSTITUTIVE LYSINE DECARBOXYLASE
Descriptor:LYSINE DECARBOXYLASE, CONSTITUTIVE
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
6BBA
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL CLPP COMPLEX WITH ACYLDEPSIPEPTIDE ADEP-28
Descriptor:ATP-dependent Clp protease proteolytic subunit, mitochondrial, Acyldepsipeptide ADEP-28
Authors:Mabanglo, M.F., Houry, W.A.
Deposit date:2017-10-17
Release date:2018-07-11
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Cell Chem Biol, 25, 2018
2F6I
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CRYSTAL STRUCTURE OF THE CLPP PROTEASE CATALYTIC DOMAIN FROM PLASMODIUM FALCIPARUM
Descriptor:ATP-dependent CLP protease, putative
Authors:Mulichak, A., Loppnau, P., Bray, J., Amani, M., Vedadi, M., Wasney, G., Finerty, P., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., Hui, R., Plotnikova, O., Structural Genomics Consortium (SGC)
Deposit date:2005-11-29
Release date:2005-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum.
J.Mol.Biol., 404, 2010
3NBX
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CRYSTAL STRUCTURE OF E. COLI RAVA (REGULATORY ATPASE VARIANT A) IN COMPLEX WITH ADP
Descriptor:ATPase ravA, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION
Authors:El Bakkouri, M.
Deposit date:2010-06-04
Release date:2011-01-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activity
Proc.Natl.Acad.Sci.USA, 107, 2010
6DKF
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CASEINOLYTIC PROTEASE (CLPP) FROM STAPHYLOCOCCUS AUREUS MUTANT - V7A
Descriptor:ATP-dependent Clp protease proteolytic subunit
Authors:Ripstein, Z.A., Vahidi, S., Kay, L.E., Rubinstein, J.L.
Deposit date:2018-05-29
Release date:2018-06-27
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Reversible inhibition of the ClpP protease via an N-terminal conformational switch.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018