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Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033
Descriptor:	CALCIUM ION, Collagenase 3, N-({4'-[(1-BENZOFURAN-2-YLCARBONYL)AMINO]-1,1'-BIPHENYL-4-YL}SULFONYL)-L-VALINE, ...
Authors:	Wu, J, Rush III, T.S, Hotchandani, R, Du, X, Geck, M, Collins, E, Xu, Z.B, Skotnicki, J, Levin, J.I, Lovering, F.
Deposit date:	2005-05-27
Release date:	2006-05-30
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Identification of potent and selective MMP-13 inhibitors Bioorg.Med.Chem.Lett., 15, 2005

Crystal structure of mouse BTK kinase domain in complex with compound 9a
Descriptor:	5-amino-1-[(3R)-1-cyanopiperidin-3-yl]-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazole-4-carboxamide, Tyrosine-protein kinase
Authors:	Han, S, Caspers, N, Ohren, J.O.
Deposit date:	2018-10-03
Release date:	2019-01-30
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Aminopyrazole Carboxamide Bruton's Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning. ACS Med Chem Lett, 10, 2019

CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes
Descriptor:	4-bromo-3-(carboxymethoxy)-5-{3-[cyclohexyl(phenylcarbonyl)amino]phenyl}thiophene-2-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 1
Authors:	Xu, W, Wu, J.
Deposit date:	2008-04-22
Release date:	2008-10-07
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24 Chemmedchem, 3, 2008

Crystal structure of PTP1B-inhibitor complex
Descriptor:	4-bromo-3-(carboxymethoxy)-5-{3-[cyclohexyl(methylcarbamoyl)amino]phenyl}thiophene-2-carboxylic acid, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Xu, W, Wu, J.
Deposit date:	2008-04-19
Release date:	2008-10-07
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24 Chemmedchem, 3, 2008