Author results

1XBS
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CRYSTAL STRUCTURE OF HUMAN DIM2: A DIM1-LIKE PROTEIN
Descriptor:Dim1-like protein
Authors:Simeoni, F., Arvai, A., Hopfner, K.-P., Bello, P., Gondeau, C., Heitz, F., Tainer, J., Divita, G.
Deposit date:2004-08-31
Release date:2005-08-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical Characterization and Crystal Structure of a Dim1 Family Associated Protein: Dim2
Biochemistry, 44, 2005
1XEW
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STRUCTURAL BIOCHEMISTRY OF ATP-DRIVEN DIMERIZATION AND DNA STIMULATED ACTIVATION OF SMC ATPASES.
Descriptor:SMC protein
Authors:Lammens, A., Schele, A., Hopfner, K.-P.
Deposit date:2004-09-13
Release date:2004-12-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases
Curr.Biol., 14, 2004
1XEX
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STRUCTURAL BIOCHEMISTRY OF ATP-DRIVEN DIMERIZATION AND DNA STIMULATED ACTIVATION OF SMC ATPASES.
Descriptor:SMC protein, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lammens, A., Schele, A., Hopfner, K.-P.
Deposit date:2004-09-13
Release date:2004-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases
Curr.Biol., 14, 2004
2B2N
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STRUCTURE OF TRANSCRIPTION-REPAIR COUPLING FACTOR
Descriptor:Transcription-repair coupling factor, SODIUM ION, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ...
Authors:Assenmacher, N., Wenig, K., Lammens, A., Hopfner, K.-P.
Deposit date:2005-09-19
Release date:2006-01-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs
J.Mol.Biol., 355, 2006
3EIK
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DOUBLE STRANDED DNA BINDING PROTEIN
Descriptor:TATA-box-binding protein, 1,2-ETHANEDIOL
Authors:Cui, S., Wollmann, P., Moldt, M., Hopfner, K.-P.
Deposit date:2008-09-16
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:structural studies of ecTBP
To be Published
3G9A
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GREEN FLUORESCENT PROTEIN BOUND TO MINIMIZER NANOBODY
Descriptor:Green fluorescent protein, Minimizer
Authors:Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U.
Deposit date:2009-02-13
Release date:2009-12-08
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.614 Å)
Cite:Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
3K1K
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GREEN FLUORESCENT PROTEIN BOUND TO ENHANCER NANOBODY
Descriptor:Green Fluorescent Protein, Enhancer
Authors:Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U.
Deposit date:2009-09-28
Release date:2009-12-08
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
3L51
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CRYSTAL STRUCTURE OF THE MOUSE CONDENSIN HINGE DOMAIN
Descriptor:Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4, GLYCEROL
Authors:Griese, J.J., Hopfner, K.-P.
Deposit date:2009-12-21
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.506 Å)
Cite:Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins
Nucleic Acids Res., 38, 2010
3M7N
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ARCHAEOGLOBUS FULGIDUS EXOSOME WITH RNA BOUND TO THE ACTIVE SITE
Descriptor:Putative uncharacterized protein AF_0206, Probable exosome complex exonuclease 1, Probable exosome complex exonuclease 2, ...
Authors:Hartung, S., Hopfner, K.-P.
Deposit date:2010-03-16
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
Nucleic Acids Res., 38, 2010
3M85
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ARCHAEOGLOBUS FULGIDUS EXOSOME Y70A WITH RNA BOUND TO THE ACTIVE SITE
Descriptor:Putative uncharacterized protein AF_0206, Probable exosome complex exonuclease 1, Probable exosome complex exonuclease 2, ...
Authors:Hartung, S., Hopfner, K.-P.
Deposit date:2010-03-17
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
Nucleic Acids Res., 38, 2010
4Y42
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CYANASE (CYNS) FROM SERRATIA PROTEAMACULANS
Descriptor:Cyanate hydratase, GLYCEROL
Authors:Butryn, A., Hopfner, K.-P.
Deposit date:2015-02-10
Release date:2015-04-08
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Serendipitous crystallization and structure determination of cyanase (CynS) from Serratia proteamaculans
Acta Crystallogr.,Sect.F, 71, 2015
1II7
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CRYSTAL STRUCTURE OF P. FURIOSUS MRE11 WITH MANGANESE AND DAMP
Descriptor:Mre11 nuclease, MANGANESE (II) ION, SULFATE ION, ...
Authors:Hopfner, K.-P., Karcher, A., Craig, L., Woo, T.T., Carney, J.P., Tainer, J.A.
Deposit date:2001-04-20
Release date:2001-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Cell(Cambridge,Mass.), 105, 2001
1II8
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CRYSTAL STRUCTURE OF THE P. FURIOSUS RAD50 ATPASE DOMAIN
Descriptor:Rad50 ABC-ATPase, PHOSPHATE ION
Authors:Hopfner, K.-P., Karcher, A., Craig, L., Woo, T.T., Carney, J.P., Tainer, J.A.
Deposit date:2001-04-20
Release date:2001-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Cell(Cambridge,Mass.), 105, 2001
1RFN
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HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE
Descriptor:PROTEIN (COAGULATION FACTOR IX), CALCIUM ION, P-AMINO BENZAMIDINE, ...
Authors:Hopfner, K.-P., Lang, A., Karcher, A., Sichler, K., Kopetzki, E., Brandstetter, H., Huber, R., Bode, W., Engh, R.A.
Deposit date:1999-04-19
Release date:1999-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding.
Structure Fold.Des., 7, 1999
1TGO
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THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS
Descriptor:PROTEIN (THERMOSTABLE B DNA POLYMERASE)
Authors:Hopfner, K.-P., Eichinger, A., Engh, R.A., Laue, F., Ankenbauer, W., Huber, R., Angerer, B.
Deposit date:1999-02-23
Release date:1999-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius.
Proc.Natl.Acad.Sci.USA, 96, 1999
3PP3
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EPITOPE CHARACTERIZATION AND CRYSTAL STRUCTURE OF GA101 PROVIDE INSIGHTS INTO THE MOLECULAR BASIS FOR THE TYPE I / TYPE II DISTINCTION OF ANTI- CD20 ANTIBODIES
Descriptor:GA101 Fab heavy chain, GA101 Fab light chain
Authors:Hopfner, K.-P., Lammens, A.
Deposit date:2010-11-24
Release date:2011-04-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (2.508 Å)
Cite:Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood, 118, 2011
3PP4
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EPITOPE CHARACTERIZATION AND CRYSTAL STRUCTURE OF GA101 PROVIDE INSIGHTS INTO THE MOLECULAR BASIS FOR THE TYPE I / TYPE II DISTINCTION OF ANTI- CD20 ANTIBODIES
Descriptor:GA101 Fab heavy chain, GA101 Fab light chain, B-lymphocyte antigen CD20, ...
Authors:Hopfner, K.-P., Lammens, A.
Deposit date:2010-11-24
Release date:2011-04-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Blood, 118, 2011
4WVY
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DOUBLE-HETEROHEXAMERIC RINGS OF FULL-LENGTH RVB1(ATP)/RVB2(APO)
Descriptor:RuvB-like 1, RuvB-like 2, ADENOSINE-5'-TRIPHOSPHATE
Authors:Hopfner, K.-P., Lakomek, K.
Deposit date:2014-11-08
Release date:2015-02-18
Last modified:2015-03-11
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural Basis for Dodecameric Assembly States and Conformational Plasticity of the Full-Length AAA+ ATPases Rvb1Rvb2.
Structure, 23, 2015
3J15
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MODEL OF RIBOSOME-BOUND ARCHAEAL PELOTA AND ABCE1
Descriptor:Protein pelota, ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Becker, T., Franckenberg, S., Wickles, S., Shoemaker, C.J., Anger, A.M., Armache, J.-P., Sieber, H., Ungewickell, C., Berninghausen, O., Daberkow, I., Karcher, A., Thomm, M., Hopfner, K.-P., Green, R., Beckmann, R.
Deposit date:2011-12-12
Release date:2012-02-22
Last modified:2018-08-22
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Nature, 482, 2012
3J16
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MODELS OF RIBOSOME-BOUND DOM34P AND RLI1P AND THEIR RIBOSOMAL BINDING PARTNERS
Descriptor:Dom34p, Rli1p, 28S ribosomal RNA, ...
Authors:Becker, T., Franckenberg, S., Wickles, S., Shoemaker, C.J., Anger, A.M., Armache, J.-P., Sieber, H., Ungewickell, C., Berninghausen, O., Daberkow, I., Karcher, A., Thomm, M., Hopfner, K.-P., Green, R., Beckmann, R.
Deposit date:2011-12-12
Release date:2012-02-22
Last modified:2012-05-30
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Nature, 482, 2012
3OC3
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CRYSTAL STRUCTURE OF THE MOT1 N-TERMINAL DOMAIN IN COMPLEX WITH TBP
Descriptor:HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Wollmann, P., Cui, S., Viswanathan, R., Berninghausen, O., Wells, M.N., Moldt, M., Witte, G., Butryn, A., Wendler, P., Beckmann, R., Auble, D.T., Hopfner, K.-P.
Deposit date:2010-08-09
Release date:2011-07-13
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
3OCI
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CRYSTAL STRUCTURE OF TBP (TATA BOX BINDING PROTEIN)
Descriptor:TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 1,2-ETHANEDIOL
Authors:Cui, S., Wollmann, P., Moldt, M., Hopfner, K.-P.
Deposit date:2010-08-10
Release date:2011-07-13
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
3TBK
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MOUSE RIG-I ATPASE DOMAIN
Descriptor:RIG-I Helicase Domain, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL
Authors:Civril, F., Bennett, M.D., Hopfner, K.-P.
Deposit date:2011-08-07
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling.
Embo Rep., 12, 2011
3TJ1
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CRYSTAL STRUCTURE OF RNA POLYMERASE I TRANSCRIPTION INITIATION FACTOR RRN3
Descriptor:RNA polymerase I-specific transcription initiation factor RRN3
Authors:Blattner, C., Jennebach, S., Herzog, F., Mayer, A., Cheung, A.C.M., Witte, G., Lorenzen, K., Hopfner, K.-P., Heck, A.J.R., Aebersold, R., Cramer, P.
Deposit date:2011-08-23
Release date:2011-09-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
4FO0
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HUMAN ACTIN-RELATED PROTEIN ARP8 IN ITS ATP-BOUND STATE
Descriptor:Actin-related protein 8, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Gerhold, C.B., Lakomek, K., Seifert, F.U., Hopfner, K.-P.
Deposit date:2012-06-20
Release date:2012-09-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Actin-related protein 8 and its contribution to nucleosome binding.
Nucleic Acids Res., 40, 2012
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