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1D2O
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CRYSTAL STRUCTURE OF A SINGLE B REPEAT UNIT (B1) OF COLLAGEN BINDING SURFACE PROTEIN (CNA) OF STAPHYLOCOCCUS AUREUS.
Descriptor:COLLAGEN ADHESIN
Authors:Deivanayagam, C.C.S., Rich, R.L., Hook, M., Narayana, S.V.L.
Deposit date:1999-09-25
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein.
Structure Fold.Des., 8, 2000
1D2P
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CRYSTAL STRUCTURE OF TWO B REPEAT UNITS (B1B2) OF THE COLLAGEN BINDING PROTEIN (CNA) OF STAPHYLOCOCCUS AUREUS
Descriptor:COLLAGEN ADHESIN
Authors:Deivanayagam, C.C.S., Rich, R.L., Hook, M., Narayana, S.V.L.
Deposit date:1999-09-25
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein.
Structure Fold.Des., 8, 2000
1N67
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CLUMPING FACTOR A FROM STAPHYLOCOCCUS AUREUS
Descriptor:Clumping Factor, MAGNESIUM ION
Authors:Deivanayagam, C.C.S., Wann, E.R., Chen, W., Carson, M., Rajashankar, K.R., Hook, M., Narayana, S.V.L.
Deposit date:2002-11-08
Release date:2003-03-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A
Embo J., 21, 2002
1G5Z
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CRYSTAL STRUCTURE OF LYME DISEASE ANTIGEN OUTER SURFACE PROTEIN C (OSPC) FROM BORRELIA BURGDORFERI STRAIN N40
Descriptor:OUTER SURFACE PROTEIN C
Authors:Eicken, C., Sharma, V., Klabunde, T., Owens, R.T., Pikas, D.S., Hook, M., Sacchettini, J.C.
Deposit date:2000-11-02
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi.
J.Biol.Chem., 276, 2001
1O9A
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SOLUTION STRUCTURE OF THE COMPLEX OF 1F12F1 FROM FIBRONECTIN WITH B3 FROM FNBB FROM S. DYSGALACTIAE
Descriptor:FIBRONECTIN, FIBRONECTIN BINDING PROTEIN
Authors:Schwarz-Linek, U., Werner, J.M., Pickford, A.R., Pilka, E.S., Gurusiddappa, S., Briggs, J.A.G., Hook, M., Campbell, I.D., Potts, J.R.
Deposit date:2002-12-11
Release date:2003-05-08
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper.
Nature, 423, 2003
1R17
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CRYSTAL STRUCTURE ANALYSIS OF S.EPIDERMIDIS ADHESIN SDRG BINDING TO FIBRINOGEN (ADHESIN-LIGAND COMPLEX)
Descriptor:fibrinogen-binding protein SdrG, fibrinopeptide B, CALCIUM ION
Authors:Ponnuraj, K., Bowden, M.G., Davis, S., Gurusiddappa, S., Moore, D., Choe, D., Xu, Y., Hook, M., Narayana, S.V.L.
Deposit date:2003-09-23
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
1R19
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CRYSTAL STRUCTURE ANALYSIS OF S.EPIDERMIDIS ADHESIN SDRG BINDING TO FIBRINOGEN (APO STRUCTURE)
Descriptor:fibrinogen-binding protein SdrG
Authors:Ponnuraj, K., Bowden, M.G., Davis, S., Gurusiddappa, S., Moore, D., Choe, D., Xu, Y., Hook, M., Narayana, S.V.L.
Deposit date:2003-09-23
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
2RAL
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CRYSTAL STRUCTURE ANALYSIS OF DOUBLE CYSTEINE MUTANT OF S.EPIDERMIDIS ADHESIN SDRG: EVIDENCE FOR THE DOCK,LOCK AND LATCH LIGAND BINDING MECHANISM
Descriptor:Serine-aspartate repeat-containing protein G
Authors:Ponnuraj, K., Sthanam, N., Bowden, M.G., Hook, M.
Deposit date:2007-09-17
Release date:2007-11-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.
J.Biol.Chem., 283, 2008
2VR3
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF FIBRINOGEN BINDING TO CLFA FROM STAPHYLOCCCUS AUREUS
Descriptor:CLUMPING FACTOR A, FIBRINOGEN GAMMA-CHAIN
Authors:Ganesh, V.K., Rivera, J.J., Smeds, E., Bowden, M.G., Wann, E.R., Gurusidappa, S., Fitzgerald, J.R., Hook, M.
Deposit date:2008-03-25
Release date:2009-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A Structural Model of the Staphylococcus Aureus Clfa-Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics.
Plos Pathog., 4, 2008
3AU0
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF CLFB:LIGAND INTERACTIONS
Descriptor:Clumping factor B, MAGNESIUM ION
Authors:Ganesh, V.K., Barbu, E.M., Deivanayagam, C.C.S., Le, B., Anderson, A.S., Matsuka, Y., Lin, S.L., Foster, T.F., Narayana, S.V.L., Hook, M.
Deposit date:2011-01-28
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and biochemical characterization of ClfB:ligand interactions
To be published
1QC5
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I DOMAIN FROM INTEGRIN ALPHA1-BETA1
Descriptor:PROTEIN (ALPHA1 BETA1 INTEGRIN), MAGNESIUM ION
Authors:Deivanayagam, C.C., Narayana, S.V.
Deposit date:1999-05-17
Release date:2000-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM.
J.Biol.Chem., 274, 1999
2F68
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CRYSTAL STRUCTURE OF COLLAGEN ADHESIN (CNA) FROM S. AUREUS
Descriptor:Collagen adhesin
Authors:Zong, Y., Narayana, S.V.L.
Deposit date:2005-11-28
Release date:2006-12-12
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen.
Embo J., 24, 2005
2F6A
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COLLAGEN ADHESIN AND COLLAGEN COMPLEX STRUCTURE
Descriptor:Collagen adhesin, Collagen
Authors:Zong, Y., Narayana, S.L.V.
Deposit date:2005-11-28
Release date:2006-12-12
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen.
Embo J., 24, 2005
1AMX
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COLLAGEN-BINDING DOMAIN FROM A STAPHYLOCOCCUS AUREUS ADHESIN
Descriptor:COLLAGEN ADHESIN
Authors:Symersky, J., Narayana, S.
Deposit date:1997-06-19
Release date:1998-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the collagen-binding domain from a Staphylococcus aureus adhesin.
Nat.Struct.Biol., 4, 1997
2Z1P
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THE ENTEROCOCCUS FAECALIS MSCRAMM ACE BINDS ITS LIGANDS BY THE COLLAGEN HUG MODEL
Descriptor:Collagen adhesin protein
Authors:Ponnuraj, K.
Deposit date:2007-05-11
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model
J.Biol.Chem., 282, 2007
3ASW
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF CLFB:LIGAND INTERACTIONS
Descriptor:Clumping factor B, Tail region derived peptide
Authors:Ganesh, V.K.
Deposit date:2010-12-22
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical characterization of ClfB:ligand interactions
To be published
3AT0
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF CLFB:LIGAND INTERACTIONS
Descriptor:Clumping factor B, C-terminal alpha chain peptide
Authors:Ganesh, V.K.
Deposit date:2010-12-23
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical characterization of ClfB:ligand interactions
To be published
5JQ6
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CRYSTAL STRUCTURE OF CLFA IN COMPLEX WITH THE FAB FRAGMENT OF TEFIBAZUMAB
Descriptor:Clumping factor A, Tefibazumab FAB FRAGMENT HEAVY CHAIN, Tefibazumab FAB FRAGMENT LIGHT CHAIN
Authors:Ganesh, V.K.
Deposit date:2016-05-04
Release date:2017-01-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.
EBioMedicine, 13, 2016